Reviewed, UniProtKB/Swiss-Prot Q9JX24 (DADA_NEIMA)

Names and origin

Protein names

Recommended name:
    D-amino acid dehydrogenase small subunit
    EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	NMA0092

Organism

Neisseria meningitidis serogroup A [Complete proteome] [HAMAP]

Taxonomic identifier

65699 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity. HAMAP MF_01202
Sequence similarities	Belongs to the dadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 418	418	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_0000166135
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9JX24-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 944530C24FA0F50D	FASTA	418	46,604
	10 20 30 40 50 60 MKVLVLGAGV AGVSSAWYLA EAGHEVTVID RAEGVAMETS FANAGQLSYG YTTPWAAPGI 70 80 90 100 110 120 PTKALKWLFK SHPPLLFRPD GSLYQIEWLW QMLQHCTAAR YQINKERMVR MSEYSREMFR 130 140 150 160 170 180 RFEAQTGMNF EGRKKGTLQI FRQTKEVEAA KQDIAVLERY GVPYRRLKPE ECAEFEPALA 190 200 210 220 230 240 RVTAKIAGGL HLPADATGDC RLFTENLYKL CQEKGVRFHF NQTISRIDHN GLRIKTVETE 250 260 270 280 290 300 TGRFEADAVV CALGCFSRTV LAQVDLNLPI YPVKGYSLTL PVTNSDGAPV STVLDESYKV 310 320 330 340 350 360 AITRFNNRIR VGGMAELSGY AIKLPEKRRE TLALVVNDLF PEGGDLNQTL FWSGLRPMTP 370 380 390 400 410 DSTPLIGRTR FDNLFLNTGH GTLGWTMSLG SAKLTADIVS GKDTEIRSDD LSLSRYQA

References

[1]

"Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491." Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M., Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K., Leather S. , Moule S., Mungall K.L., Quail M.A., Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G., Barrell B.G. Nature 404:502-506(2000) [PubMed: 10761919] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z2491 / Serogroup A / Serotype 4A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL157959 Genomic DNA. Translation: CAM07411.1.
PIR	C82001.
RefSeq	YP_002341644.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	906107.
GenomeReviews	Gene locus NMA0092 in contig AL157959_GR.
KEGG	nma:NMA0092.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG729204.
OMA	TIMDETH.
Enzyme and pathway databases
BioCyc	NMEN122587:NMA0092-MONOMER.
BRENDA	1.4.99.1. 292829.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR006076. FAD-dep_OxRdtase. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_NEIMA

Accession

Primary (citable) accession number: Q9JX24
Secondary accession number(s): A1INV4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	October 1, 2000
Last modified:	January 19, 2010
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)