Q9JWJ7 (RSMI_NEIMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase I
EC=2.1.1.198

Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase
rRNA (cytidine-2'-O-)-methyltransferase RsmI

Gene names

Name:	rsmI
Ordered Locus Names:	NMA0342

Organism

Neisseria meningitidis serogroup A [Complete proteome] [HAMAP]

Taxonomic identifier

65699 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877
Catalytic activity	S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877
Subcellular location	Cytoplasm Potential HAMAP MF_01877.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmI family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 291	291	Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877		PRO_0000211948

Sequences

	Sequence		Length	Mass (Da)
	Q9JWJ7 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 96081C989844C0D0	FASTA	291	31,321
	10 20 30 40 50 60 MFQKHLQKAS DSVVGGTLYV VATPIGNLAD ITLRALAVLQ KADIICAEDT RVTAQLLSAY 70 80 90 100 110 120 GIQGKLVSVR EHNERQMADK IVGYLSDGMV VAQVSDAGTP AVCDPGAKLA RRVREVGFKV 130 140 150 160 170 180 VPVVGASAVM AALSVAGVAG SDFYFNGFVP PKSGERRKLF AKWVRVAFPV VMFETPHRIG 190 200 210 220 230 240 ATLADMAELF PERRLMLARE ITKTFETFLS GTVGEIQTAL AADGNQSRGE MVLVLYPAQD 250 260 270 280 290 EKHEGLSESA QNIMKILTAE LPTKQAAELA AKITGEGKKA LYDLALSWKN K

References

[1]

"Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491." Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M., Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K., Leather S. , Moule S., Mungall K.L., Quail M.A., Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G., Barrell B.G. Nature 404:502-506(2000) [PubMed: 10761919] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z2491 / Serogroup A / Serotype 4A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL157959 Genomic DNA. Translation: CAM07642.1.
PIR	B82030.
RefSeq	YP_002341856.1. NC_003116.1.
3D structure databases
ProteinModelPortal	Q9JWJ7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBNEIT00000001476; EBNEIP00000001476; EBNEIG00000001476.
GeneID	906347.
GenomeReviews	Gene locus NMA0342 in contig AL157959_GR.
KEGG	nma:NMA0342.
PATRIC	20361348. VBINeiMen132687_0399.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000021223.
HOGENOM	HBG529058.
OMA	IASDRFC.
ProtClustDB	CLSK878377.
Enzyme and pathway databases
BioCyc	NMEN122587:NMA0342-MONOMER.
Family and domain databases
HAMAP	MF_01877. 16SrRNA_methyltr_I. [Tree]
InterPro	IPR000878. 4pyrrol_Mease. IPR014777. 4pyrrole_Mease_sub1. IPR008189. rRNA_ssu_MeTfrase_I. IPR018063. SAM_MeTrfase_RsmI_CS. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
KO	K07056.
PANTHER	PTHR21091:SF18. PTHR21091:SF18. 1 hit.
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
PIRSF	PIRSF005917. MTase_YraL. 1 hit.
SUPFAM	SSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMs	TIGR00096. TIGR00096. 1 hit.
PROSITE	PS01296. RSMI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMI_NEIMA

Accession

Primary (citable) accession number: Q9JWJ7
Secondary accession number(s): A1IPH3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 2, 2001
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program