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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.By similarity

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC:3.6.1.41)
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase
Diadenosine tetraphosphatase
Gene namesi
Name:apaH
Ordered Locus Names:NMA0860
OrganismiNeisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Taxonomic identifieri122587 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000626 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001979991 – 276Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST276

Structurei

3D structure databases

ProteinModelPortaliQ9JVF4
SMRiQ9JVF4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.Curated

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q9JVF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHYAIGDIQ GCFDELTALL GKIGFNHGTD TLWLTGDIVN RGPKSLETLQ
60 70 80 90 100
FCIRHENSVQ IVLGNHDLHL LAVGYGEGAP KRSDTIEPIL KHPDGRKMLD
110 120 130 140 150
WLRAQPLLIR EGNRVMVHAG ILPQWRITKA ESLAGEAEAE LRGKKYVKFF
160 170 180 190 200
SKMYGNKPAA WDEGLEGYAR LRFIVNAFTR MRALTFKNEL DFDYKSTVKK
210 220 230 240 250
MPLYLRPWFK APDRQNLDHT IIFGHWSSLG YTNADNVISL DTGALWGGQL
260 270
TAVNLETEEI TQVQAAGGID WKSFTK
Length:276
Mass (Da):31,116
Last modified:October 1, 2000 - v1
Checksum:i8D71929FA25C5471
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157959 Genomic DNA Translation: CAM08097.1
PIRiH81931
RefSeqiWP_002231975.1, NC_003116.1

Genome annotation databases

EnsemblBacteriaiCAM08097; CAM08097; NMA0860
KEGGinma:NMA0860

Similar proteinsi

Entry informationi

Entry nameiAPAH_NEIMA
AccessioniPrimary (citable) accession number: Q9JVF4
Secondary accession number(s): A1IQR3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: October 1, 2000
Last modified: March 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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