Q9JU03 (SUHB_NEIMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inositol-1-monophosphatase
Short name=I-1-Pase
Short name=IMPase
Short name=Inositol-1-phosphatase
EC=3.1.3.25

Gene names

Name:	suhB
Ordered Locus Names:	NMA1559

Organism

Neisseria meningitidis serogroup A [Complete proteome] [HAMAP]

Taxonomic identifier

65699 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Myo-inositol phosphate + H2O = myo-inositol + phosphate.
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the inositol monophosphatase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	inositol monophosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 261	261	Inositol-1-monophosphatase		PRO_0000142566
Regions
	Region	86 – 89	4	Substrate binding By similarity
Sites
	Metal binding	67	1	Magnesium 1 By similarity
	Metal binding	84	1	Magnesium 1 By similarity
	Metal binding	84	1	Magnesium 2 By similarity
	Metal binding	86	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	87	1	Magnesium 2 By similarity
	Metal binding	212	1	Magnesium 2 By similarity
	Binding site	67	1	Substrate By similarity
	Binding site	183	1	Substrate By similarity
	Binding site	212	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9JU03 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 23DCA23F3DD63734	FASTA	261	28,497
	10 20 30 40 50 60 MNPFLNTAFK AARRAGQMMI RAAGNLDAVK TDSKAFNDFV SDVDRNSEII LVEALKEAYP 70 80 90 100 110 120 HHKITCEESG SHGKAAAEYE WIIDPLDGTT NFLHGHPQYA ISMALLHKGV LQEALVYAPE 130 140 150 160 170 180 RNDVYMASRG KGALLNDRRI RVSNRIELNR CLIGTGFPVV DQSMMDKYLV ILKDFLAKTA 190 200 210 220 230 240 GGRREGAASL DLCAVATGRF DGFFEFNLKP WDIAAGALIV QEAGGIVTDM SGEDGWLESG 250 260 DIVAANPKVL AQMLKIISAH V

References

[1]

"Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491." Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M., Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K., Leather S. , Moule S., Mungall K.L., Quail M.A., Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G., Barrell B.G. Nature 404:502-506(2000) [PubMed: 10761919] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z2491 / Serogroup A / Serotype 4A.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL157959 Genomic DNA. Translation: CAM08704.1.
PIR	B81848.
RefSeq	YP_002342876.1. NC_003116.1.
3D structure databases
ProteinModelPortal	Q9JU03.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBNEIT00000000921; EBNEIP00000000921; EBNEIG00000000921.
GeneID	907947.
GenomeReviews	Gene locus NMA1559 in contig AL157959_GR.
KEGG	nma:NMA1559.
PATRIC	20364206. VBINeiMen132687_1807.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000021157.
HOGENOM	HBG730251.
OMA	TGFPFKQ.
ProtClustDB	CLSK878014.
Enzyme and pathway databases
BioCyc	NMEN122587:NMA1559-MONOMER.
Family and domain databases
InterPro	IPR020583. Inositol_monoP_metal-BS. IPR000760. Inositol_monophosphatase. IPR020550. Inositol_monophosphatase_CS. IPR022337. Inositol_monophosphatase_SuhB. [Graphical view]
KO	K01092.
PANTHER	PTHR20854. Inositol_P. 1 hit.
Pfam	PF00459. Inositol_P. 1 hit. [Graphical view]
PRINTS	PR00377. IMPHPHTASES. PR01959. SBIMPHPHTASE.
PROSITE	PS00629. IMP_1. 1 hit. PS00630. IMP_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SUHB_NEIMA

Accession

Primary (citable) accession number: Q9JU03
Secondary accession number(s): A1ISE8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program