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Q9JM83 (CALM4_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Calmodulin-4
Alternative name(s):
Calcium-binding protein Dd112
Gene names
Name:Calm4
Synonyms:Dd112
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length148 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Implicated in the early stage of ectopic ossification.

Sequence similarities

Contains 4 EF-hand domains.

Ontologies

Keywords
   DomainRepeat
   LigandCalcium
Metal-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functioncalcium ion binding

Inferred from direct assay PubMed 12970338. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 148148Calmodulin-4
PRO_0000073856

Regions

Domain8 – 4336EF-hand 1
Domain44 – 7936EF-hand 2
Domain80 – 11536EF-hand 3
Domain116 – 14833EF-hand 4
Calcium binding21 – 32121 Potential
Calcium binding57 – 68122 Potential
Calcium binding93 – 104123 Potential

Experimental info

Sequence conflict91E → V in BAB22914. Ref.2
Sequence conflict1241M → V in BAB22914. Ref.2
Sequence conflict146 – 1483VEN → I in BAA95412. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9JM83 [UniParc].

Last modified June 1, 2001. Version 2.
Checksum: 2AE22BC738AD2F9D

FASTA14816,767
        10         20         30         40         50         60 
MSHGFTKEEV AEFQAAFNRF DKNKDGHISV EELGDVMKQL GKNLPEKDLK ALISKLDTDG 

        70         80         90        100        110        120 
DGKISFEEFL TAIEKYKKGH RAGELRAVFN VLDQNGDGYI TVDELKESLS KLGESLSQEE 

       130        140 
LEDMIRVADV DQDGKVKYEE FVRLHVEN 

« Hide

References

« Hide 'large scale' references
[1]"DD112, a novel mouse gene implicated in the early stage of ectopic ossification."
Ikegawa S., Nakamura Y.
Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Tongue.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB036744 Genomic DNA. Translation: BAA95412.1.
AK009956 mRNA. Translation: BAB26608.1.
AK009664 mRNA. Translation: BAB26425.1.
AK003648 mRNA. Translation: BAB22914.1.
CCDSCCDS26215.1.
RefSeqNP_064420.2. NM_020036.4.
UniGeneMm.21075.

3D structure databases

ProteinModelPortalQ9JM83.
SMRQ9JM83. Positions 5-144.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000041636.

PTM databases

PhosphoSiteQ9JM83.

Proteomic databases

MaxQBQ9JM83.
PRIDEQ9JM83.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000042219; ENSMUSP00000041636; ENSMUSG00000033765.
GeneID80796.
KEGGmmu:80796.
UCSCuc007pjb.1. mouse.

Organism-specific databases

CTD80796.
MGIMGI:1931464. Calm4.

Phylogenomic databases

eggNOGCOG5126.
GeneTreeENSGT00670000097718.
HOGENOMHOG000233018.
HOVERGENHBG012180.
InParanoidQ9JM83.
KOK02183.
OMATLECCKE.
OrthoDBEOG7GFB71.
PhylomeDBQ9JM83.
TreeFamTF339519.

Gene expression databases

BgeeQ9JM83.
CleanExMM_CALM4.
GenevestigatorQ9JM83.

Family and domain databases

Gene3D1.10.238.10. 1 hit.
InterProIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamPF13499. EF-hand_7. 2 hits.
[Graphical view]
SMARTSM00054. EFh. 4 hits.
[Graphical view]
PROSITEPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio350136.
PROQ9JM83.
SOURCESearch...

Entry information

Entry nameCALM4_MOUSE
AccessionPrimary (citable) accession number: Q9JM83
Secondary accession number(s): Q9CR31, Q9D1E9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot