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Q9JM83

- CALM4_MOUSE

UniProt

Q9JM83 - CALM4_MOUSE

Protein

Calmodulin-4

Gene

Calm4

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Implicated in the early stage of ectopic ossification.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Calcium bindingi21 – 32121PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi57 – 68122PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi93 – 104123PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. calcium ion binding Source: MGI

    Keywords - Ligandi

    Calcium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Calmodulin-4
    Alternative name(s):
    Calcium-binding protein Dd112
    Gene namesi
    Name:Calm4
    Synonyms:Dd112
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:1931464. Calm4.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 148148Calmodulin-4PRO_0000073856Add
    BLAST

    Proteomic databases

    MaxQBiQ9JM83.
    PRIDEiQ9JM83.

    PTM databases

    PhosphoSiteiQ9JM83.

    Expressioni

    Gene expression databases

    BgeeiQ9JM83.
    CleanExiMM_CALM4.
    GenevestigatoriQ9JM83.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000041636.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9JM83.
    SMRiQ9JM83. Positions 5-144.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini8 – 4336EF-hand 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini44 – 7936EF-hand 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini80 – 11536EF-hand 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini116 – 14833EF-hand 4PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 4 EF-hand domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG5126.
    GeneTreeiENSGT00670000097718.
    HOGENOMiHOG000233018.
    HOVERGENiHBG012180.
    InParanoidiQ9JM83.
    KOiK02183.
    OMAiTLECCKE.
    OrthoDBiEOG7GFB71.
    PhylomeDBiQ9JM83.
    TreeFamiTF339519.

    Family and domain databases

    Gene3Di1.10.238.10. 1 hit.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view]
    PfamiPF13499. EF-hand_7. 2 hits.
    [Graphical view]
    SMARTiSM00054. EFh. 4 hits.
    [Graphical view]
    PROSITEiPS00018. EF_HAND_1. 3 hits.
    PS50222. EF_HAND_2. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9JM83-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSHGFTKEEV AEFQAAFNRF DKNKDGHISV EELGDVMKQL GKNLPEKDLK    50
    ALISKLDTDG DGKISFEEFL TAIEKYKKGH RAGELRAVFN VLDQNGDGYI 100
    TVDELKESLS KLGESLSQEE LEDMIRVADV DQDGKVKYEE FVRLHVEN 148
    Length:148
    Mass (Da):16,767
    Last modified:June 1, 2001 - v2
    Checksum:i2AE22BC738AD2F9D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti9 – 91E → V in BAB22914. (PubMed:16141072)Curated
    Sequence conflicti124 – 1241M → V in BAB22914. (PubMed:16141072)Curated
    Sequence conflicti146 – 1483VEN → I in BAA95412. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB036744 Genomic DNA. Translation: BAA95412.1.
    AK009956 mRNA. Translation: BAB26608.1.
    AK009664 mRNA. Translation: BAB26425.1.
    AK003648 mRNA. Translation: BAB22914.1.
    CCDSiCCDS26215.1.
    RefSeqiNP_064420.2. NM_020036.4.
    UniGeneiMm.21075.

    Genome annotation databases

    EnsembliENSMUST00000042219; ENSMUSP00000041636; ENSMUSG00000033765.
    GeneIDi80796.
    KEGGimmu:80796.
    UCSCiuc007pjb.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB036744 Genomic DNA. Translation: BAA95412.1 .
    AK009956 mRNA. Translation: BAB26608.1 .
    AK009664 mRNA. Translation: BAB26425.1 .
    AK003648 mRNA. Translation: BAB22914.1 .
    CCDSi CCDS26215.1.
    RefSeqi NP_064420.2. NM_020036.4.
    UniGenei Mm.21075.

    3D structure databases

    ProteinModelPortali Q9JM83.
    SMRi Q9JM83. Positions 5-144.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000041636.

    PTM databases

    PhosphoSitei Q9JM83.

    Proteomic databases

    MaxQBi Q9JM83.
    PRIDEi Q9JM83.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000042219 ; ENSMUSP00000041636 ; ENSMUSG00000033765 .
    GeneIDi 80796.
    KEGGi mmu:80796.
    UCSCi uc007pjb.1. mouse.

    Organism-specific databases

    CTDi 80796.
    MGIi MGI:1931464. Calm4.

    Phylogenomic databases

    eggNOGi COG5126.
    GeneTreei ENSGT00670000097718.
    HOGENOMi HOG000233018.
    HOVERGENi HBG012180.
    InParanoidi Q9JM83.
    KOi K02183.
    OMAi TLECCKE.
    OrthoDBi EOG7GFB71.
    PhylomeDBi Q9JM83.
    TreeFami TF339519.

    Miscellaneous databases

    NextBioi 350136.
    PROi Q9JM83.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9JM83.
    CleanExi MM_CALM4.
    Genevestigatori Q9JM83.

    Family and domain databases

    Gene3Di 1.10.238.10. 1 hit.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view ]
    Pfami PF13499. EF-hand_7. 2 hits.
    [Graphical view ]
    SMARTi SM00054. EFh. 4 hits.
    [Graphical view ]
    PROSITEi PS00018. EF_HAND_1. 3 hits.
    PS50222. EF_HAND_2. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DD112, a novel mouse gene implicated in the early stage of ectopic ossification."
      Ikegawa S., Nakamura Y.
      Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Tongue.

    Entry informationi

    Entry nameiCALM4_MOUSE
    AccessioniPrimary (citable) accession number: Q9JM83
    Secondary accession number(s): Q9CR31, Q9D1E9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 98 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3