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Q9JLX8 (Q9JLX8_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Edn1 RGD 2532
OrganismRattus norvegicus (Rat) EMBL AAF31762.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length105 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processbody fluid secretion

Inferred from electronic annotation. Source: Ensembl

calcium-mediated signaling

Inferred from electronic annotation. Source: Ensembl

cartilage development

Inferred from electronic annotation. Source: Ensembl

dorsal/ventral pattern formation

Inferred from electronic annotation. Source: Ensembl

glucose transport

Inferred from electronic annotation. Source: Ensembl

heart development

Inferred from electronic annotation. Source: Ensembl

in utero embryonic development

Inferred from electronic annotation. Source: Ensembl

inositol phosphate-mediated signaling

Inferred from electronic annotation. Source: Ensembl

middle ear morphogenesis

Inferred from electronic annotation. Source: Ensembl

negative regulation of cAMP biosynthetic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of cellular protein metabolic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of nitric-oxide synthase biosynthetic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Ensembl

neural crest cell development

Inferred from electronic annotation. Source: Ensembl

nitric oxide transport

Inferred from electronic annotation. Source: Ensembl

patterning of blood vessels

Inferred from electronic annotation. Source: Ensembl

peptide hormone secretion

Inferred from electronic annotation. Source: Ensembl

phosphatidylinositol 3-kinase signaling

Inferred from electronic annotation. Source: Ensembl

phospholipase D-activating G-protein coupled receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of JUN kinase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of cardiac muscle hypertrophy

Inferred from electronic annotation. Source: Ensembl

positive regulation of cell migration

Inferred from electronic annotation. Source: Ensembl

positive regulation of cell size

Inferred from electronic annotation. Source: Ensembl

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of heart rate

Inferred from electronic annotation. Source: Ensembl

positive regulation of hormone secretion

Inferred from electronic annotation. Source: Ensembl

positive regulation of mitosis

Inferred from electronic annotation. Source: Ensembl

positive regulation of prostaglandin-endoperoxide synthase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of receptor biosynthetic process

Inferred from electronic annotation. Source: Ensembl

positive regulation of renal sodium excretion

Inferred from electronic annotation. Source: Ensembl

positive regulation of sarcomere organization

Inferred from electronic annotation. Source: Ensembl

positive regulation of smooth muscle cell proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of urine volume

Inferred from electronic annotation. Source: Ensembl

prostaglandin biosynthetic process

Inferred from electronic annotation. Source: Ensembl

protein kinase C deactivation

Inferred from electronic annotation. Source: Ensembl

protein kinase C-activating G-protein coupled receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

regulation of pH

Inferred from electronic annotation. Source: Ensembl

regulation of systemic arterial blood pressure by endothelin

Inferred from electronic annotation. Source: Ensembl

regulation of vasoconstriction

Inferred from electronic annotation. Source: InterPro

respiratory gaseous exchange

Inferred from electronic annotation. Source: Ensembl

response to hypoxia

Inferred from electronic annotation. Source: Ensembl

rhythmic excitation

Inferred from electronic annotation. Source: Ensembl

vein smooth muscle contraction

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: Ensembl

extracellular space

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAF31762.1
Non-terminal residue1051 EMBL AAF31762.1

Sequences

Sequence LengthMass (Da)Tools
Q9JLX8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: CE368E686F828573

FASTA10512,202
        10         20         30         40         50         60 
RSKRSLKDLL PTKTTDQGNR CQCAHQKDKK CWNFCQADKE LRAQSTMQKG VKDFKKGKPC 

        70         80         90        100 
PKLGKKCIYQ QLVEGRKLRR LEAISNSIKT SFRVAKLKAE LYRDQ 

« Hide

References

[1]"Increased Local Expression of ET-1 Enhances a-agonist Induced Contraction of Rat Aorta After Prolonged Hypoxia In Vivo."
Toporsian M., Auer G., Zacour M., Cernacek P., Ward M.E.
Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Sprague-Dawley EMBL AAF31762.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF122903 mRNA. Translation: AAF31762.1.
UniGeneRn.10918.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

RGD2532. Edn1.

Phylogenomic databases

HOVERGENHBG051441.
InParanoidQ9JLX8.

Gene expression databases

ArrayExpressQ9JLX8.
GenevestigatorQ9JLX8.

Family and domain databases

InterProIPR019764. Endothelin_toxin_CS.
IPR001928. Endothln-like_toxin.
[Graphical view]
SMARTSM00272. END. 1 hit.
[Graphical view]
PROSITEPS00270. ENDOTHELIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9JLX8_RAT
AccessionPrimary (citable) accession number: Q9JLX8
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: March 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)