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Protein
Submitted name:

Pleiomorphic adenoma gene-like 1, isoform CRA_d

Gene

Plagl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
  • regulation of gene expression Source: MGI
  • skeletal muscle cell differentiation Source: MGI
  • transcription from RNA polymerase II promoter Source: MGI
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Pleiomorphic adenoma gene-like 1, isoform CRA_dImported
Submitted name:
Protein Plagl1Imported
Submitted name:
Zinc finger protein ZAC1Imported
Gene namesi
Name:Plagl1Imported
Synonyms:Zac1Imported
ORF Names:mCG_12864Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1100874. Plagl1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112847.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 3128C2H2-typeInterPro annotationAdd
BLAST
Domaini32 – 6130C2H2-typeInterPro annotationAdd
BLAST
Domaini62 – 8928C2H2-typeInterPro annotationAdd
BLAST
Domaini91 – 11828C2H2-typeInterPro annotationAdd
BLAST
Domaini156 – 18328C2H2-typeInterPro annotationAdd
BLAST
Domaini184 – 21229C2H2-typeInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00390000013640.
HOGENOMiHOG000294191.
HOVERGENiHBG053608.
KOiK19485.
OMAiMLPMQPM.
OrthoDBiEOG71K62Q.
TreeFamiTF332024.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR027775. C2H2_Znf_fam.
IPR027770. PLAGL1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR10032. PTHR10032. 2 hits.
PTHR10032:SF227. PTHR10032:SF227. 2 hits.
SMARTiSM00355. ZnF_C2H2. 7 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JLQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPFRCQKCG KSFVTLEKFT IHNYSHSRER PFKCSKAECG KAFVSKYKLM
60 70 80 90 100
RHMATHSPQK IHQCTHCEKT FNRKDHLKNH LQTHDPNKIS YACDDCGKKY
110 120 130 140 150
HTMLGYKRHL ALHSASNGDL TCGVCTLELG STEVLLDHLK SHAEEKANQA
160 170 180 190 200
PREKKYQCDH CDRCFYTRKD VRRHLVVHTG CKDFLCQFCA QRFGRKDHLT
210 220 230 240 250
RHTKKTHSQE LMQENMQAGD YQSNFQLIAP STSFQIKVDP MPPFQLGAAP
260 270 280 290 300
ENGLDGGLPP EVHGLVLAAP EEAPQPMPPL EPLEPLEPLE PLEPMQSLEP
310 320 330 340 350
LQPLEPMQPL EPMQPLEPMQ PLEPLEPLEP MQPLEPMQPL EPMQPMLPMQ
360 370 380 390 400
PMQPMQPMQP MLPMQPMLPM QPMQPMQPML PMPEPSFTLH PGVVPTSPPP
410 420 430 440 450
IILQEHKYNP VPTSYAPFVG MPVKADGKAF CNVGFFEEFP LQEPQAPLKF
460 470 480 490 500
NPCFEMPMEG FGKVTLSKEL LVDAVNIAIP ASLEISSLLG FWQLPPPTPQ
510 520 530 540 550
NGFVNSTIPV GPGEPLPHRI TCLAQQQPPP LPPPPPLPLP QPLPVPQPLP
560 570 580 590 600
QPQMQPQFQL QIQPQMQPQM QLQPLQLQLP QLLPQLQPQQ QPDPEPEPEP
610 620 630 640 650
EPEPEPEPEP EPEPEPEPEP EPEPEEEQEE AEEEAEEGAE EGAEPEAQAE
660 670 680 690 700
EEEEEEEAEE PQPEEAQIAV SAVNLGQPPL PPTPHIFTAG SNTAILPHFH

HAFR
Length:704
Mass (Da):79,214
Last modified:October 1, 2000 - v1
Checksum:i3AF88262D504FA80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL691505 Genomic DNA. No translation available.
AL713985 Genomic DNA. No translation available.
AF147785 mRNA. Translation: AAF34245.1.
CH466562 Genomic DNA. Translation: EDL03510.1.
RefSeqiNP_033564.2. NM_009538.2.
UniGeneiMm.287857.

Genome annotation databases

EnsembliENSMUST00000121646; ENSMUSP00000112847; ENSMUSG00000019817.
GeneIDi22634.
KEGGimmu:22634.
UCSCiuc007ekm.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL691505 Genomic DNA. No translation available.
AL713985 Genomic DNA. No translation available.
AF147785 mRNA. Translation: AAF34245.1.
CH466562 Genomic DNA. Translation: EDL03510.1.
RefSeqiNP_033564.2. NM_009538.2.
UniGeneiMm.287857.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112847.

Protocols and materials databases

DNASUi22634.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000121646; ENSMUSP00000112847; ENSMUSG00000019817.
GeneIDi22634.
KEGGimmu:22634.
UCSCiuc007ekm.2. mouse.

Organism-specific databases

CTDi5325.
MGIiMGI:1100874. Plagl1.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00390000013640.
HOGENOMiHOG000294191.
HOVERGENiHBG053608.
KOiK19485.
OMAiMLPMQPM.
OrthoDBiEOG71K62Q.
TreeFamiTF332024.

Miscellaneous databases

ChiTaRSiPlagl1. mouse.
NextBioi303013.
SOURCEiSearch...

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR027775. C2H2_Znf_fam.
IPR027770. PLAGL1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR10032. PTHR10032. 2 hits.
PTHR10032:SF227. PTHR10032:SF227. 2 hits.
SMARTiSM00355. ZnF_C2H2. 7 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Mouse Zac1, a transcriptional coactivator and repressor for nuclear receptors."
    Huang S.-M., Stallcup M.R.
    Mol. Cell. Biol. 20:1855-1867(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ9JLQ4_MOUSE
AccessioniPrimary (citable) accession number: Q9JLQ4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.