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Q9JLP6

- Q9JLP6_RAT

UniProt

Q9JLP6 - Q9JLP6_RAT

Protein
Submitted name:

Protein kinase C, zeta

Gene

Prkcz

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. protein serine/threonine kinase activity Source: Ensembl
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. microtubule cytoskeleton organization Source: Ensembl
    2. negative regulation of insulin receptor signaling pathway Source: Ensembl
    3. negative regulation of peptidyl-tyrosine phosphorylation Source: Ensembl
    4. negative regulation of protein complex assembly Source: Ensembl
    5. peptidyl-serine phosphorylation Source: Ensembl
    6. positive regulation of ERK1 and ERK2 cascade Source: Ensembl
    7. positive regulation of interleukin-10 secretion Source: Ensembl
    8. positive regulation of interleukin-13 secretion Source: Ensembl
    9. positive regulation of interleukin-4 production Source: Ensembl
    10. positive regulation of interleukin-5 secretion Source: Ensembl
    11. positive regulation of T-helper 2 cell cytokine production Source: Ensembl
    12. positive regulation of T-helper 2 cell differentiation Source: Ensembl
    13. protein localization to plasma membrane Source: Ensembl

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein kinase C, zetaImported
    Gene namesi
    Name:PrkczImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi3399. Prkcz.

    Subcellular locationi

    GO - Cellular componenti

    1. apical cortex Source: Ensembl
    2. apical plasma membrane Source: Ensembl
    3. myelin sheath abaxonal region Source: Ensembl
    4. nuclear envelope Source: Ensembl
    5. nuclear matrix Source: Ensembl
    6. protein complex Source: Ensembl
    7. tight junction Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ9JLP6.
    GenevestigatoriQ9JLP6.

    Interactioni

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG104837.

    Family and domain databases

    InterProiIPR000270. OPR_PB1.
    IPR012233. PKC_zeta.
    [Graphical view]
    PANTHERiPTHR24357:SF60. PTHR24357:SF60. 1 hit.
    PfamiPF00564. PB1. 1 hit.
    [Graphical view]
    SMARTiSM00666. PB1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9JLP6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSRTDPKMD RSGGRVRLKA HYGGDILITS VDPTTTFQDL CEEVRDMCGL    50
    HQQHPLTLKW VDSEGDPCTV SSQMELEEAF RLACQGRDEV LIIHVFPSIP 100
    EQPGMPCPGE DKSIYRRGAR RWRKLYRANG HLFQAKRFNR 140
    Length:140
    Mass (Da):16,070
    Last modified:October 1, 2000 - v1
    Checksum:i51E6B242AB4DE92F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei140 – 1401Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AH009282 Genomic DNA. Translation: AAF68171.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AH009282 Genomic DNA. Translation: AAF68171.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi Q9JLP6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 3399. Prkcz.

    Phylogenomic databases

    HOVERGENi HBG104837.

    Gene expression databases

    ArrayExpressi Q9JLP6.
    Genevestigatori Q9JLP6.

    Family and domain databases

    InterProi IPR000270. OPR_PB1.
    IPR012233. PKC_zeta.
    [Graphical view ]
    PANTHERi PTHR24357:SF60. PTHR24357:SF60. 1 hit.
    Pfami PF00564. PB1. 1 hit.
    [Graphical view ]
    SMARTi SM00666. PB1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Rat Protein Kinase C Zeta Gene Contains Alternative Promoters for Generation of Dual Transcripts with 5'-end Heterogeneity."
      Marshall B.S., Powell C.T.
      Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.

    Entry informationi

    Entry nameiQ9JLP6_RAT
    AccessioniPrimary (citable) accession number: Q9JLP6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2000
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)