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Protein

Vasopressin V1b receptor

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Vasopressin V1b receptorUniRule annotation
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei38 – 5922HelicalUniRule annotationAdd
BLAST
Transmembranei71 – 8919HelicalUniRule annotationAdd
BLAST
Transmembranei109 – 13022HelicalUniRule annotationAdd
BLAST
Transmembranei151 – 17424HelicalUniRule annotationAdd
BLAST
Transmembranei199 – 22224HelicalUniRule annotationAdd
BLAST
Transmembranei281 – 30323HelicalUniRule annotationAdd
BLAST
Transmembranei315 – 33521HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiQ9JLP2.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027690.

Structurei

3D structure databases

ProteinModelPortaliQ9JLP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini51 – 335285G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG105710.

Family and domain databases

InterProiIPR015076. DUF1856.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001817. Vasoprsn_rcpt.
IPR000628. Vprs_rcpt_V1B.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
PF08983. DUF1856. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00896. VASOPRESSINR.
PR00897. VASOPRSNV1BR.
SMARTiSM01164. DUF1856. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JLP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSEPSWTAT PSPGGTLFVP NTTTPWLGRD EELAKVEIGI LATVLVLATG
60 70 80 90 100
GNLAVLLILG LQGHKRSRMH LFVLHLALTD LGVALFQVLP QLLWDITYRF
110 120 130 140 150
QGSDLLCRAV KYLQVLSMFA STYMLLAMTL DRYLAVCHPL RSLQQPSQST
160 170 180 190 200
YPLIAAPWLL AAILSLPQVF IFSLREVIQG SGVLDCWADF YFSWGPRAYI
210 220 230 240 250
TWTTMAIFVL PVVVLTACYG LICHEIYKNL KVKTQAGREE RRGWPKSSSS
260 270 280 290 300
AAAAATRGLP SRVSSISTIS RAKIRTVKMT FVIVLAYIAC WAPFFSVQMW
310 320 330 340 350
SVWDENAPNE DSTNVAFTIS MLLGNLSSCC NPWIYMGFNS HLLPRSLSHR
360 370 380 390 400
ACCRGSKPRV HRQLSNSSLA SRRTTLLTHT CGPSTLRLSL NLSLNAKPKP
410 420
AGSLKDLEQV DGEATMETSI S
Length:421
Mass (Da):46,516
Last modified:October 1, 2000 - v1
Checksum:iE867DA6C160F596F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF152534, AF152533 Genomic DNA. Translation: AAF73221.1.
UniGeneiMm.89986.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF152534, AF152533 Genomic DNA. Translation: AAF73221.1.
UniGeneiMm.89986.

3D structure databases

ProteinModelPortaliQ9JLP2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027690.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9JLP2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG105710.

Family and domain databases

InterProiIPR015076. DUF1856.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001817. Vasoprsn_rcpt.
IPR000628. Vprs_rcpt_V1B.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
PF08983. DUF1856. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00896. VASOPRESSINR.
PR00897. VASOPRSNV1BR.
SMARTiSM01164. DUF1856. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9JLP2_MOUSE
AccessioniPrimary (citable) accession number: Q9JLP2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.