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Protein

Vasopressin V1b receptor

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Vasopressin V1b receptorUniRule annotation
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei38 – 59HelicalUniRule annotationAdd BLAST22
Transmembranei71 – 89HelicalUniRule annotationAdd BLAST19
Transmembranei109 – 130HelicalUniRule annotationAdd BLAST22
Transmembranei151 – 174HelicalUniRule annotationAdd BLAST24
Transmembranei199 – 222HelicalUniRule annotationAdd BLAST24
Transmembranei281 – 303HelicalUniRule annotationAdd BLAST23
Transmembranei315 – 335HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiQ9JLP2.

Structurei

3D structure databases

ProteinModelPortaliQ9JLP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 335G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST285

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG105710.

Family and domain databases

InterProiView protein in InterPro
IPR015076. DUF1856.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001817. Vasoprsn_rcpt.
IPR000628. Vprs_rcpt_V1B.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PF08983. DUF1856. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00896. VASOPRESSINR.
PR00897. VASOPRSNV1BR.
SMARTiView protein in SMART
SM01164. DUF1856. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9JLP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSEPSWTAT PSPGGTLFVP NTTTPWLGRD EELAKVEIGI LATVLVLATG
60 70 80 90 100
GNLAVLLILG LQGHKRSRMH LFVLHLALTD LGVALFQVLP QLLWDITYRF
110 120 130 140 150
QGSDLLCRAV KYLQVLSMFA STYMLLAMTL DRYLAVCHPL RSLQQPSQST
160 170 180 190 200
YPLIAAPWLL AAILSLPQVF IFSLREVIQG SGVLDCWADF YFSWGPRAYI
210 220 230 240 250
TWTTMAIFVL PVVVLTACYG LICHEIYKNL KVKTQAGREE RRGWPKSSSS
260 270 280 290 300
AAAAATRGLP SRVSSISTIS RAKIRTVKMT FVIVLAYIAC WAPFFSVQMW
310 320 330 340 350
SVWDENAPNE DSTNVAFTIS MLLGNLSSCC NPWIYMGFNS HLLPRSLSHR
360 370 380 390 400
ACCRGSKPRV HRQLSNSSLA SRRTTLLTHT CGPSTLRLSL NLSLNAKPKP
410 420
AGSLKDLEQV DGEATMETSI S
Length:421
Mass (Da):46,516
Last modified:October 1, 2000 - v1
Checksum:iE867DA6C160F596F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH009399 Genomic DNA. Translation: AAF73221.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9JLP2_MOUSE
AccessioniPrimary (citable) accession number: Q9JLP2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: July 5, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)