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Protein

Aryl-hydrocarbon-interacting protein-like 1

Gene

Aipl1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be important in protein trafficking and/or protein folding and stabilization.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Aryl-hydrocarbon-interacting protein-like 1
Gene namesi
Name:Aipl1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi70906. Aipl1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000753471 – 328Aryl-hydrocarbon-interacting protein-like 1Add BLAST328

Proteomic databases

PaxDbiQ9JLG9.
PRIDEiQ9JLG9.

Expressioni

Tissue specificityi

Highly expressed in retina.

Gene expression databases

GenevisibleiQ9JLG9. RN.

Interactioni

Subunit structurei

Interacts with NUB1.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010533.

Structurei

3D structure databases

ProteinModelPortaliQ9JLG9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 145PPIase FKBP-typeAdd BLAST93
Repeati178 – 211TPR 1Add BLAST34
Repeati230 – 263TPR 2Add BLAST34
Repeati264 – 297TPR 3Add BLAST34

Sequence similaritiesi

Contains 1 PPIase FKBP-type domain.Curated
Contains 3 TPR repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiKOG0545. Eukaryota.
ENOG410YGYV. LUCA.
GeneTreeiENSGT00390000001289.
HOGENOMiHOG000007366.
HOVERGENiHBG004198.
InParanoidiQ9JLG9.
KOiK17767.
OMAiVIEHCNE.
OrthoDBiEOG091G0C69.
PhylomeDBiQ9JLG9.
TreeFamiTF314507.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR031209. AIPL1.
IPR001179. PPIase_FKBP_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR11242:SF2. PTHR11242:SF2. 1 hit.
PfamiPF00254. FKBP_C. 1 hit.
[Graphical view]
SMARTiSM00028. TPR. 2 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JLG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVSLLLNVE GVKKTILHGG TGELPNFITG SRVTFHFRTM KCDEERTVID
60 70 80 90 100
DSKQVGQPMN IIIGNMFKLE VWETLLTSMR LGEVAEFWCD TIHTGVYPML
110 120 130 140 150
SRSLRQVAEG KDPTSWHVHT CGLANMFAYH TLGYEDLDEL QKEPQPLIFL
160 170 180 190 200
IELLQVEAPN EYQRETWNLN NEERMQAVPL LHGEGNRLYK LGRYDQAATK
210 220 230 240 250
YQEAIVCLRN LQTKEKPWEV EWLKLEKMIN TLILNYCQCL LKKEEYYEVL
260 270 280 290 300
EHTSDILRHH PGIVKAYYMR ARAHAEVWNA EEAKADLEKV LELEPSMRKA
310 320
VLRELRLLES RLADKQEEER QRCRSMLG
Length:328
Mass (Da):38,294
Last modified:October 1, 2000 - v1
Checksum:iE9BC3A4084F64A0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF180340 mRNA. Translation: AAF26707.1.
RefSeqiNP_067601.1. NM_021590.1.
XP_017452988.1. XM_017597499.1.
UniGeneiRn.8243.

Genome annotation databases

EnsembliENSRNOT00000010533; ENSRNOP00000010533; ENSRNOG00000007889.
GeneIDi59110.
KEGGirno:59110.
UCSCiRGD:70906. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF180340 mRNA. Translation: AAF26707.1.
RefSeqiNP_067601.1. NM_021590.1.
XP_017452988.1. XM_017597499.1.
UniGeneiRn.8243.

3D structure databases

ProteinModelPortaliQ9JLG9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010533.

Proteomic databases

PaxDbiQ9JLG9.
PRIDEiQ9JLG9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000010533; ENSRNOP00000010533; ENSRNOG00000007889.
GeneIDi59110.
KEGGirno:59110.
UCSCiRGD:70906. rat.

Organism-specific databases

CTDi23746.
RGDi70906. Aipl1.

Phylogenomic databases

eggNOGiKOG0545. Eukaryota.
ENOG410YGYV. LUCA.
GeneTreeiENSGT00390000001289.
HOGENOMiHOG000007366.
HOVERGENiHBG004198.
InParanoidiQ9JLG9.
KOiK17767.
OMAiVIEHCNE.
OrthoDBiEOG091G0C69.
PhylomeDBiQ9JLG9.
TreeFamiTF314507.

Miscellaneous databases

PROiQ9JLG9.

Gene expression databases

GenevisibleiQ9JLG9. RN.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR031209. AIPL1.
IPR001179. PPIase_FKBP_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR11242:SF2. PTHR11242:SF2. 1 hit.
PfamiPF00254. FKBP_C. 1 hit.
[Graphical view]
SMARTiSM00028. TPR. 2 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAIPL1_RAT
AccessioniPrimary (citable) accession number: Q9JLG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.