Unreviewed, UniProtKB/TrEMBL Q9JLE1 (Q9JLE1_MOUSE)

Names and origin

Protein names

Submitted name:
    P53 tumor suppressor EMBL AAF43276.1

Gene names

Name:

Trp53 MGI 98834

Organism

Mus musculus (Mouse) EMBL AAF43276.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	43 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	B cell lineage commitment Inferred from mutant phenotype. Source: MGI DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis Inferred from genetic interaction. Source: MGI G1 DNA damage checkpoint Inferred from mutant phenotype. Source: MGI T cell differentiation in the thymus Inferred from genetic interaction. Source: MGI T cell lineage commitment Inferred from mutant phenotype. Source: MGI T cell proliferation during immune response Inferred from genetic interaction. Source: MGI cell aging Inferred from genetic interaction. Source: MGI cellular response to UV Inferred from genetic interaction. Source: MGI central nervous system development Inferred from genetic interaction. Source: MGI chromosome organization Inferred from genetic interaction. Source: MGI double-strand break repair Inferred from mutant phenotype. Source: MGI gastrulation Inferred from genetic interaction. Source: MGI in utero embryonic development Inferred from genetic interaction. Source: MGI negative regulation of DNA replication Inferred from direct assay. Source: MGI negative regulation of apoptosis Inferred from mutant phenotype. Source: MGI negative regulation of fibroblast proliferation Inferred from direct assay. Source: MGI negative regulation of neuroblast proliferation Inferred from genetic interaction. Source: MGI negative regulation of transcription from RNA polymerase II promoter Inferred from direct assay. Source: MGI positive regulation of neuron apoptosis Inferred from direct assay. Source: MGI positive regulation of transcription from RNA polymerase II promoter Inferred from direct assay. Source: MGI protein import into nucleus, translocation Inferred from direct assay. Source: MGI rRNA transcription Inferred from genetic interaction. Source: MGI regulation of mitochondrial membrane permeability Inferred from genetic interaction. Source: MGI release of cytochrome c from mitochondria Inferred from direct assay. Source: MGI response to X-ray Inferred from direct assay. Source: MGI response to drug Inferred from direct assay. Source: MGI response to gamma radiation Inferred from direct assay. Source: MGI response to salt stress Inferred from genetic interaction. Source: MGI
Cellular component	cytosol Inferred from direct assay. Source: MGI nucleus Inferred from direct assay. Source: MGI replication fork Inferred from direct assay. Source: MGI
Molecular function	protein binding Inferred from physical interaction. Source: MGI transcription factor activity Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAF43276.1
	Non-terminal residue	43	1	EMBL AAF43276.1

Sequences

	Sequence		Length	Mass (Da)
	Q9JLE1-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: D70E9E15774609A1	FASTA	43	4,799
	10 20 30 40 EALELKDAHA TEESGDSRAH SSYLKTKKGQ STSRHKKTMV KKV

References

[1]	"Species-specific regulation of alternative splicing in the C-terminal region of the p53 tumor suppressor gene." Laverdiere M., Beaudoin J., Lavigueur A. Nucleic Acids Res. 28:1489-1497(2000) [PubMed: 10684946] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF190269 Genomic DNA. Translation: AAF43276.1.
IPI	IPI00406306.
UniGene	Mm.222
3D structure databases
HSSP	HSSP built from PDB template 1DT7 based on UniProtKB Q9NP68.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9JLE1.
Genome annotation databases
Ensembl	ENSMUST00000005371; ENSMUSP00000005371; ENSMUSG00000059552; Mus musculus. [Genome view] ENSMUST00000108657; ENSMUSP00000104297; ENSMUSG00000059552; Mus musculus. [Genome view] ENSMUST00000108658; ENSMUSP00000104298; ENSMUSG00000059552; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:98834. Trp53.
Phylogenomic databases
HOVERGEN	Q9JLE1.
Gene expression databases
ArrayExpress	Q9JLE1.
Bgee	Q9JLE1.
Genevestigator	Q9JLE1.
Family and domain databases
InterPro	IPR015551. Trp53. [Graphical view]
PANTHER	PTHR11447. Trp53. 1 hit.
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q9JLE1_MOUSE

Accession

Primary (citable) accession number: Q9JLE1

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)