P53 tumor suppressor - Rattus norvegicus (Rat)

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Unreviewed, UniProtKB/TrEMBL Q9JLD8 (Q9JLD8_RAT)

Last modified January 19, 2010. Version 31. History...

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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
P53 tumor suppressor EMBL AAF43277.1

Gene names

Name:

Tp53 RGD 3889

Organism

Rattus norvegicus (Rat) EMBL AAF43277.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	39 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	aging Inferred from expression pattern. Source: RGD negative regulation of cell growth Traceable author statement. Source: RGD negative regulation of smooth muscle cell proliferation Inferred from mutant phenotype. Source: RGD positive regulation of apoptosis Inferred from mutant phenotype. Source: RGD positive regulation of cell cycle Inferred from mutant phenotype. Source: RGD positive regulation of leukocyte migration Inferred from mutant phenotype. Source: RGD regulation of intracellular pH Inferred from mutant phenotype. Source: RGD regulation of transcription from RNA polymerase II promoter Traceable author statement. Source: RGD response to UV Inferred from expression pattern. Source: RGD response to X-ray Inferred from expression pattern. Source: RGD response to amino acid stimulus Inferred from expression pattern. Source: RGD response to caffeine Inferred from expression pattern. Source: RGD response to cytokine stimulus Inferred from expression pattern. Source: RGD response to drug Inferred from expression pattern. Source: RGD response to hyperoxia Inferred from expression pattern. Source: RGD response to metal ion Inferred from expression pattern. Source: RGD response to oxidative stress Inferred from expression pattern. Source: RGD response to retinoic acid Inferred from expression pattern. Source: RGD response to vitamin B3 Inferred from expression pattern. Source: RGD wound healing Inferred from expression pattern. Source: RGD
Cellular component	chromatin Inferred from direct assay. Source: RGD cytosol Inferred from direct assay. Source: RGD mitochondrion Inferred from direct assay. Source: RGD transcription factor complex Inferred from direct assay. Source: RGD
Molecular function	RNA polymerase II transcription factor activity Traceable author statement. Source: RGD sequence-specific DNA binding Inferred from direct assay. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

1

EMBL AAF43277.1

Sequences

Sequence

Length

Mass (Da)

Tools

Q9JLD8-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 04150E27223E59F5
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39

4,285

        10         20         30 
EALELKDARA AEESGDSRAH SSLQPRTFQA LIKKESPNC

References

[1]	"Species-specific regulation of alternative splicing in the C-terminal region of the p53 tumor suppressor gene." Laverdiere M., Beaudoin J., Lavigueur A. Nucleic Acids Res. 28:1489-1497(2000) [PubMed: 10684946] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Kidney EMBL AAF43277.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF190270 Genomic DNA. Translation: AAF43277.1.
IPI	IPI00189385.
UniGene	Rn.54443
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9JLD8.
Genome annotation databases
Ensembl	ENSRNOT00000014471; ENSRNOP00000014470; ENSRNOG00000010756; Rattus norvegicus. [Genome view]
Phylogenomic databases
HOVERGEN	Q9JLD8.
Gene expression databases
ArrayExpress	Q9JLD8.
Genevestigator	Q9JLD8.
Family and domain databases
InterPro	IPR015551. Trp53. [Graphical view]
PANTHER	PTHR11447. Trp53. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9JLD8_RAT

Accession

Primary (citable) accession number: Q9JLD8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 19, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information