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Protein
Submitted name:

Cytochrome P450 CYP2D22

Gene

Cyp2d22

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-MMU-211981. Xenobiotics.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 CYP2D22Imported
Submitted name:
Cytochrome P450, family 2, subfamily d, polypeptide 22Imported
Submitted name:
MCG20388, isoform CRA_bImported
Gene namesi
Name:Cyp2d22Imported
ORF Names:mCG_20388Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1929474. Cyp2d22.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 28HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000061740.

Interactioni

Protein-protein interaction databases

IntActiQ9JKY7. 1 interactor.
MINTiMINT-4130200.
STRINGi10090.ENSMUSP00000023083.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00880000137854.
HOVERGENiHBG015789.
KOiK07414.
OMAiDIELQGF.
OrthoDBiEOG091G0BT8.
TreeFamiTF352043.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008069. Cyt_P450_E_grp-I_CYP2D-like.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR01686. EP450ICYP2D.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9JKY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLPTGAELW PIAIFTVIFL ILVNLMHWRQ RWTAHYPPGP MPWPVLGNLL
60 70 80 90 100
HMDFQNMPAG FQKLRGRYGD LFSLQLASES VVVLNGLTAL REALVKHSED
110 120 130 140 150
TADRPPLHFN DLLGFGPRSQ GIVLARYGPA WRQQRRFSVS TMHHFGLGKK
160 170 180 190 200
SLEQWVTEEA RCLCAAFADH TGHPFSPNTL LDKAVCNVIA SLLYACRFEY
210 220 230 240 250
DDPRFIRLLG LLKETLKEEA GFLPMFLNVF PMLLRIPGLV GKVFPGKRAF
260 270 280 290 300
VTMLDELLAE HKTTWDPTQP PRDLTDAFLA EVEKAKGNPE SSFNDENLRT
310 320 330 340 350
VVGDLFSAGM VTTSTTLSWA LMLMILHPDV QRRVQQEIDE VIGQVQCPEM
360 370 380 390 400
ADQARMPYTN AVIHEVQRFA DILPLGVPHK TSRDIELQGF LIPKGTTLIT
410 420 430 440 450
NLSSALKDET VWEKPLCFHP EHFLDAQGHF VKPEAFMPFS AGRRSCLGEP
460 470 480 490 500
LARMELFLFF TCLLQRFSIS VPDGQPQPSD HGVFRALTTP CPYQLCALPR
Length:500
Mass (Da):56,468
Last modified:October 1, 2000 - v1
Checksum:iFACB35854CBC3F1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104325 Genomic DNA. No translation available.
AC113593 Genomic DNA. No translation available.
AF221525 mRNA. Translation: AAF34652.1.
CH466550 Genomic DNA. Translation: EDL04505.1.
RefSeqiNP_001156944.1. NM_001163472.1.
NP_062797.3. NM_019823.4.
UniGeneiMm.474216.

Genome annotation databases

EnsembliENSMUST00000023083; ENSMUSP00000023083; ENSMUSG00000061740.
GeneIDi56448.
KEGGimmu:56448.
UCSCiuc007wzd.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ9JKY7_MOUSE
AccessioniPrimary (citable) accession number: Q9JKY7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: August 30, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported