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Q9JKW8

- Q9JKW8_MOUSE

UniProt

Q9JKW8 - Q9JKW8_MOUSE

Protein
Submitted name:

Cyclin dependent kinase 4

Gene

CDK4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. cyclin-dependent protein serine/threonine kinase activity Source: Ensembl

    GO - Biological processi

    1. circadian rhythm Source: Ensembl
    2. G1/S transition of mitotic cell cycle Source: Ensembl
    3. organ regeneration Source: Ensembl
    4. positive regulation of apoptotic process Source: Ensembl
    5. positive regulation of cell size Source: Ensembl
    6. positive regulation of fibroblast proliferation Source: Ensembl
    7. positive regulation of translation Source: Ensembl
    8. response to drug Source: Ensembl
    9. response to hyperoxia Source: Ensembl
    10. response to lead ion Source: Ensembl
    11. response to testosterone Source: Ensembl
    12. response to toxic substance Source: Ensembl

    Keywords - Molecular functioni

    CyclinImported, KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cyclin dependent kinase 4Imported
    Gene namesi
    Name:CDK4Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Subcellular locationi

    GO - Cellular componenti

    1. chromatin Source: Ensembl
    2. cytosol Source: Ensembl
    3. nuclear membrane Source: Ensembl
    4. nucleolus Source: Ensembl
    5. perinuclear region of cytoplasm Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ9JKW8.
    BgeeiQ9JKW8.
    GenevestigatoriQ9JKW8.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliQ9JKW8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000233024.
    InParanoidiQ9JKW8.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9JKW8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAATRYEPVA EIGVGAYGTV YKARDPHSGH FVALKSVRVP NGGAAGGGLP   50
    VSTVREVALL RRLEAFEHPN VVRLMDVCAT SRTDRDIKVT LVFEHI 96
    Length:96
    Mass (Da):10,372
    Last modified:October 1, 2000 - v1
    Checksum:iFF8C4B8CF34F0A96
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei96 – 961Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF223390 Genomic DNA. Translation: AAF61074.1.
    UniGeneiMm.6839.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF223390 Genomic DNA. Translation: AAF61074.1 .
    UniGenei Mm.6839.

    3D structure databases

    ProteinModelPortali Q9JKW8.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi Q9JKW8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000233024.
    InParanoidi Q9JKW8.

    Gene expression databases

    ArrayExpressi Q9JKW8.
    Bgeei Q9JKW8.
    Genevestigatori Q9JKW8.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9JKW8_MOUSE
    AccessioniPrimary (citable) accession number: Q9JKW8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2000
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)