Q9JKW8 (Q9JKW8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cyclin dependent kinase 4 EMBL AAF61074.1

Gene names

Name:	Cdk4 MGI 88357
Synonyms:	CDK4 EMBL AAF61074.1

Organism

Mus musculus (Mouse) EMBL AAF61074.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	96 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Cyclin EMBL AAF61074.1 Kinase EMBL AAF61074.1 Transferase
Gene Ontology (GO)
Biological_process	G1/S transition of mitotic cell cycle Inferred from electronic annotation. Source: Compara circadian rhythm Inferred from electronic annotation. Source: Compara organ regeneration Inferred from electronic annotation. Source: Compara positive regulation of apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of cell size Inferred from electronic annotation. Source: Compara positive regulation of fibroblast proliferation Inferred from electronic annotation. Source: Compara positive regulation of translation Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara response to hyperoxia Inferred from electronic annotation. Source: Compara response to lead ion Inferred from electronic annotation. Source: Compara response to testosterone stimulus Inferred from electronic annotation. Source: Compara response to toxin Inferred from electronic annotation. Source: Compara
Cellular_component	chromatin Inferred from electronic annotation. Source: Compara cytosol Inferred from electronic annotation. Source: Compara nuclear membrane Inferred from electronic annotation. Source: Compara nucleolus Inferred from electronic annotation. Source: Compara perinuclear region of cytoplasm Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro cyclin-dependent protein serine/threonine kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	96	1	EMBL AAF61074.1

Sequences

	Sequence		Length	Mass (Da)
	Q9JKW8 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: FF8C4B8CF34F0A96	FASTA	96	10,372
	10 20 30 40 50 60 MAATRYEPVA EIGVGAYGTV YKARDPHSGH FVALKSVRVP NGGAAGGGLP VSTVREVALL 70 80 90 RRLEAFEHPN VVRLMDVCAT SRTDRDIKVT LVFEHI

References

[1]	"Identification of CDK4 as a target of c-MYC." Hermeking H., Rago C., Schuhmacher M., Li Q., Barrett J.F., Obaya A.J., O'Connell B.C., Mateyak M.K., Tam W., Kohlhuber F., Dang C.V., Sedivy J.M., Eick D., Vogelstein B., Kinzler K.W. Proc. Natl. Acad. Sci. U.S.A. 97:2229-2234(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF223390 Genomic DNA. Translation: AAF61074.1.
IPI	IPI00919157.
UniGene	Mm.6839.
3D structure databases
HSSP	HSSP built from PDB template 1JOW based on UniProtKB Q00534.
ProteinModelPortal	Q9JKW8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9JKW8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000233024.
InParanoid	Q9JKW8.
Gene expression databases
ArrayExpress	Q9JKW8.
Bgee	Q9JKW8.
Genevestigator	Q9JKW8.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	Q9JKW8.

Entry information

Entry name

Q9JKW8_MOUSE

Accession

Primary (citable) accession number: Q9JKW8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)