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Protein
Submitted name:

BRCA1

Gene

Brca1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. ubiquitin-protein transferase activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. DNA repair Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
BRCA1Imported
Gene namesi
Name:Brca1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2218. Brca1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9JKL6.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028109.

Family & Domainsi

Family and domain databases

InterProiIPR011364. BRCA1.
IPR025994. BRCA1_serine_dom.
[Graphical view]
PANTHERiPTHR13763:SF0. PTHR13763:SF0. 1 hit.
PfamiPF12820. BRCT_assoc. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9JKL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RASSLQRGTR SLLFTEDRLD AEKAEFCDRS KQSGAAVSQQ SRWADSKETC
60 70 80 90 100
NGRPVPRTEG KADPNVDSLC GRKQWNHPKS LCPENSGATT DVPWITLNSS
110 120 130 140 150
IQKVNEWFSR TGEMLTSDNA SDRRPASNAE AAVVLEVSNE VDGCFSSSKK
160 170 180 190 200
IDLVAPDPDN AVMCTSGRDF SKPVENIIND KIFGKTYQRK GSRPHLNHVT
210 220 230 240 250
EIIGTFTTEP QIIQEQPFTN KLKRKRSTCL HPEDFIKKAD LTVVQRISEN

LNQGTN
Length:256
Mass (Da):28,497
Last modified:October 1, 2000 - v1
Checksum:iAC9825619791F772
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei256 – 2561Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF234782 mRNA. Translation: AAF40440.1.
UniGeneiRn.217584.
Rn.48840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF234782 mRNA. Translation: AAF40440.1.
UniGeneiRn.217584.
Rn.48840.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028109.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi2218. Brca1.

Miscellaneous databases

NextBioi35585047.

Gene expression databases

GenevestigatoriQ9JKL6.

Family and domain databases

InterProiIPR011364. BRCA1.
IPR025994. BRCA1_serine_dom.
[Graphical view]
PANTHERiPTHR13763:SF0. PTHR13763:SF0. 1 hit.
PfamiPF12820. BRCT_assoc. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "BRCA1 Expression in the Mammary Gland Correlates with Genetic Susceptibility of Rat Strains to Mammary Cancer."
    Williams-Hill D.M., Koehler E.Y., Hill C.K.
    Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Wistar-FurthImported.

Entry informationi

Entry nameiQ9JKL6_RAT
AccessioniPrimary (citable) accession number: Q9JKL6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: April 1, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.