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Protein
Submitted name:

Apoptosis regulator BAX

Gene

Bax

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-114294. Activation, translocation and oligomerization of BAX.
R-RNO-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.

Names & Taxonomyi

Protein namesi
Submitted name:
Apoptosis regulator BAXImported
Submitted name:
Bax protein splice variant kImported
Submitted name:
RCG54570, isoform CRA_aImported
Gene namesi
Name:BaxImported
Synonyms:Bax_v1Imported
ORF Names:rCG_54570Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi2192. Bax.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei151 – 169HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000020876.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWQJ. Eukaryota.
ENOG4112738. LUCA.
GeneTreeiENSGT00730000111112.
HOGENOMiHOG000095178.
HOVERGENiHBG003606.
KOiK02159.

Family and domain databases

Gene3Di1.10.437.10. 1 hit.
InterProiView protein in InterPro
IPR026304. BAX.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020726. Bcl2_BH2_motif_CS.
IPR036834. Blc2-like_sf.
IPR026298. Blc2_fam.
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF42. PTHR11256:SF42. 1 hit.
PfamiView protein in Pfam
PF00452. Bcl-2. 1 hit.
PRINTSiPR01862. BCL2FAMILY.
SUPFAMiSSF56854. SSF56854. 1 hit.
PROSITEiView protein in PROSITE
PS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01258. BH2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9JKL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTGAFLLQG FIQDRAERMA GETPELTLEQ PPQDASTKKL SECLRRIGDE
60 70 80 90 100
LDNNMELQRM IADVDTDSPR EVFFRVAADM FADGNFNWGR VVALFYFASK
110 120 130 140 150
LVLKALCTKV PELIRTIMGW TLDFLRERLL VWIQDQGGWD GLLSYFGTPT
160 170
WQTVTIFVAG VLTASLTIWK KMG
Length:173
Mass (Da):19,661
Last modified:October 1, 2000 - v1
Checksum:iF19A45BCF642C34F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128792 Genomic DNA. No translation available.
AF235993 mRNA. Translation: AAF36411.1.
CH473979 Genomic DNA. Translation: EDM07347.1.
RefSeqiNP_058755.2. NM_017059.2.
UniGeneiRn.10668.
Rn.232358.

Genome annotation databases

EnsembliENSRNOT00000087061; ENSRNOP00000075080; ENSRNOG00000020876.
GeneIDi24887.
KEGGirno:24887.

Similar proteinsi

Entry informationi

Entry nameiQ9JKL3_RAT
AccessioniPrimary (citable) accession number: Q9JKL3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 22, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported