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Protein
Submitted name:

Apoptosis regulator BAX

Gene

Bax

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-114294. Activation, translocation and oligomerization of BAX.
R-RNO-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.

Names & Taxonomyi

Protein namesi
Submitted name:
Apoptosis regulator BAXImported
Submitted name:
Bax protein splice variant kImported
Submitted name:
RCG54570, isoform CRA_aImported
Gene namesi
Name:BaxImported
Synonyms:Bax_v1Imported
ORF Names:rCG_54570Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi2192. Bax.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei151 – 169HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000020876.
ExpressionAtlasiQ9JKL3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028328.

Structurei

3D structure databases

ProteinModelPortaliQ9JKL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWQJ. Eukaryota.
ENOG4112738. LUCA.
GeneTreeiENSGT00730000111112.
HOGENOMiHOG000095178.
HOVERGENiHBG003606.
KOiK02159.

Family and domain databases

InterProiView protein in InterPro
IPR026304. BAX.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020726. Bcl2_BH2_motif_CS.
IPR026298. Blc2_fam.
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF52. PTHR11256:SF52. 1 hit.
PfamiView protein in Pfam
PF00452. Bcl-2. 1 hit.
PRINTSiPR01862. BCL2FAMILY.
PROSITEiView protein in PROSITE
PS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01258. BH2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9JKL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTGAFLLQG FIQDRAERMA GETPELTLEQ PPQDASTKKL SECLRRIGDE
60 70 80 90 100
LDNNMELQRM IADVDTDSPR EVFFRVAADM FADGNFNWGR VVALFYFASK
110 120 130 140 150
LVLKALCTKV PELIRTIMGW TLDFLRERLL VWIQDQGGWD GLLSYFGTPT
160 170
WQTVTIFVAG VLTASLTIWK KMG
Length:173
Mass (Da):19,661
Last modified:October 1, 2000 - v1
Checksum:iF19A45BCF642C34F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128792 Genomic DNA. No translation available.
AF235993 mRNA. Translation: AAF36411.1.
CH473979 Genomic DNA. Translation: EDM07347.1.
RefSeqiNP_058755.2. NM_017059.2.
UniGeneiRn.10668.
Rn.232358.

Genome annotation databases

EnsembliENSRNOT00000087061; ENSRNOP00000075080; ENSRNOG00000020876.
GeneIDi24887.
KEGGirno:24887.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128792 Genomic DNA. No translation available.
AF235993 mRNA. Translation: AAF36411.1.
CH473979 Genomic DNA. Translation: EDM07347.1.
RefSeqiNP_058755.2. NM_017059.2.
UniGeneiRn.10668.
Rn.232358.

3D structure databases

ProteinModelPortaliQ9JKL3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028328.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000087061; ENSRNOP00000075080; ENSRNOG00000020876.
GeneIDi24887.
KEGGirno:24887.

Organism-specific databases

CTDi581.
RGDi2192. Bax.

Phylogenomic databases

eggNOGiENOG410IWQJ. Eukaryota.
ENOG4112738. LUCA.
GeneTreeiENSGT00730000111112.
HOGENOMiHOG000095178.
HOVERGENiHBG003606.
KOiK02159.

Enzyme and pathway databases

ReactomeiR-RNO-114294. Activation, translocation and oligomerization of BAX.
R-RNO-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.

Gene expression databases

BgeeiENSRNOG00000020876.
ExpressionAtlasiQ9JKL3. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR026304. BAX.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020726. Bcl2_BH2_motif_CS.
IPR026298. Blc2_fam.
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF52. PTHR11256:SF52. 1 hit.
PfamiView protein in Pfam
PF00452. Bcl-2. 1 hit.
PRINTSiPR01862. BCL2FAMILY.
PROSITEiView protein in PROSITE
PS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01258. BH2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9JKL3_RAT
AccessioniPrimary (citable) accession number: Q9JKL3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: February 15, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.