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Protein

39S ribosomal protein L39, mitochondrial

Gene

Mrpl39

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • mitochondrial genome maintenance Source: MGI
  • translation Source: MGI
  • tRNA aminoacylation for protein translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L39, mitochondrial
Short name:
L39mt
Short name:
MRP-L39
Gene namesi
Name:Mrpl39
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1351620. Mrpl39.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: MGI
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 33633639S ribosomal protein L39, mitochondrialPRO_0000087685Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei123 – 1231N6-acetyllysineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9JKF7.
MaxQBiQ9JKF7.
PaxDbiQ9JKF7.
PeptideAtlasiQ9JKF7.
PRIDEiQ9JKF7.

PTM databases

iPTMnetiQ9JKF7.
PhosphoSiteiQ9JKF7.

Expressioni

Gene expression databases

BgeeiQ9JKF7.
CleanExiMM_MRPL39.
GenevisibleiQ9JKF7. MM.

Interactioni

Protein-protein interaction databases

IntActiQ9JKF7. 1 interaction.
STRINGi10090.ENSMUSP00000112283.

Structurei

3D structure databases

ProteinModelPortaliQ9JKF7.
SMRiQ9JKF7. Positions 30-325.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L39 family.Curated

Phylogenomic databases

eggNOGiKOG1637. Eukaryota.
COG0441. LUCA.
GeneTreeiENSGT00390000002149.
HOGENOMiHOG000000683.
HOVERGENiHBG023123.
InParanoidiQ9JKF7.
KOiK17420.
OMAiPYNCAMH.
OrthoDBiEOG7T1RCK.
TreeFamiTF300858.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR012675. Beta-grasp_dom.
IPR012676. TGS-like.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
[Graphical view]
SUPFAMiSSF55186. SSF55186. 1 hit.
SSF81271. SSF81271. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9JKF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAVGRLVL RRPGAGGGAR WRFIATSPAA ELSPTELTEM RNDLFNREKS
60 70 80 90 100
RQLSLTPRTE KIEVKHVGKT DPGTVFVMNK NISTPYSCAM HLSEWYCSKS
110 120 130 140 150
ILALVDGQPW DMYKPLTKSC EIKFLTFKDP DPKEVNKAYW RSCAMMLGCV
160 170 180 190 200
IERAFKDDYV VSLVRAPEVP VIAGAFCYDV TLDKRLDEWM PTKENLRSFT
210 220 230 240 250
KDAHALIYRD LPFETLDVDA RVALEIFQHN KYKVDFIEEK ASQNPERIVK
260 270 280 290 300
LHRIGDFIDV SEGPLIPRTS VCFQYEVSAV HNLNPSQPNL IRRFQGLSLP
310 320 330
THLRAQFTIW DKLVERSRKM VTEDEVRQTE NTESTQ
Length:336
Mass (Da):38,549
Last modified:July 27, 2011 - v4
Checksum:i20F03B4A8E874E5D
GO

Sequence cautioni

The sequence AAF44697.1 differs from that shown. Reason: Frameshift at position 16. Curated
The sequence AAH12274.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAH16561.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence BAB25185.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti133 – 1331K → R in AAH16561 (PubMed:15489334).Curated
Sequence conflicti164 – 1641V → L in AAH16561 (PubMed:15489334).Curated
Sequence conflicti283 – 2831L → F in AAF44697 (Ref. 1) Curated
Sequence conflicti315 – 3151E → G in AAH16561 (PubMed:15489334).Curated
Sequence conflicti317 – 3171S → F in AAF44697 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF239728 mRNA. Translation: AAF44697.1. Sequence problems.
AK007681 mRNA. Translation: BAB25185.1. Different initiation.
CT027693 Genomic DNA. Translation: CAO78080.1.
CH466521 Genomic DNA. Translation: EDK98312.1.
BC012274 mRNA. Translation: AAH12274.1. Different initiation.
BC016561 mRNA. Translation: AAH16561.1. Different initiation.
CCDSiCCDS57035.1.
RefSeqiNP_059100.3. NM_017404.4.
UniGeneiMm.103655.

Genome annotation databases

EnsembliENSMUST00000116584; ENSMUSP00000112283; ENSMUSG00000022889.
GeneIDi27393.
KEGGimmu:27393.
UCSCiuc007zte.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF239728 mRNA. Translation: AAF44697.1. Sequence problems.
AK007681 mRNA. Translation: BAB25185.1. Different initiation.
CT027693 Genomic DNA. Translation: CAO78080.1.
CH466521 Genomic DNA. Translation: EDK98312.1.
BC012274 mRNA. Translation: AAH12274.1. Different initiation.
BC016561 mRNA. Translation: AAH16561.1. Different initiation.
CCDSiCCDS57035.1.
RefSeqiNP_059100.3. NM_017404.4.
UniGeneiMm.103655.

3D structure databases

ProteinModelPortaliQ9JKF7.
SMRiQ9JKF7. Positions 30-325.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9JKF7. 1 interaction.
STRINGi10090.ENSMUSP00000112283.

PTM databases

iPTMnetiQ9JKF7.
PhosphoSiteiQ9JKF7.

Proteomic databases

EPDiQ9JKF7.
MaxQBiQ9JKF7.
PaxDbiQ9JKF7.
PeptideAtlasiQ9JKF7.
PRIDEiQ9JKF7.

Protocols and materials databases

DNASUi27393.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000116584; ENSMUSP00000112283; ENSMUSG00000022889.
GeneIDi27393.
KEGGimmu:27393.
UCSCiuc007zte.2. mouse.

Organism-specific databases

CTDi54148.
MGIiMGI:1351620. Mrpl39.

Phylogenomic databases

eggNOGiKOG1637. Eukaryota.
COG0441. LUCA.
GeneTreeiENSGT00390000002149.
HOGENOMiHOG000000683.
HOVERGENiHBG023123.
InParanoidiQ9JKF7.
KOiK17420.
OMAiPYNCAMH.
OrthoDBiEOG7T1RCK.
TreeFamiTF300858.

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Miscellaneous databases

ChiTaRSiMrpl39. mouse.
PROiQ9JKF7.
SOURCEiSearch...

Gene expression databases

BgeeiQ9JKF7.
CleanExiMM_MRPL39.
GenevisibleiQ9JKF7. MM.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR012675. Beta-grasp_dom.
IPR012676. TGS-like.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
[Graphical view]
SUPFAMiSSF55186. SSF55186. 1 hit.
SSF81271. SSF81271. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Construction of a transcript map in the LL56-APP region of chromosome 21q21.1-21.2."
    Choi D.K., Taylor T.D., Hattori M., Sakaki Y.
    Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Pancreas.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Heart, Kidney, Liver, Pancreas and Testis.

Entry informationi

Entry nameiRM39_MOUSE
AccessioniPrimary (citable) accession number: Q9JKF7
Secondary accession number(s): A6X954, Q91YK5, Q9D8U5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: July 27, 2011
Last modified: July 6, 2016
This is version 133 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.