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Protein
Submitted name:

CD40 protein

Gene

Cd40

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. antigen binding Source: RGD

GO - Biological processi

  1. cellular response to lipopolysaccharide Source: RGD
  2. inflammatory response Source: RGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CD40 proteinImported
Gene namesi
Name:Cd40Imported
Synonyms:Tnfrsf5Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi619830. Cd40.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: RGD
  2. cytoplasm Source: RGD
  3. extracellular space Source: RGD
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9JKE0.

Structurei

3D structure databases

ProteinModelPortaliQ9JKE0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG005117.
PhylomeDBiQ9JKE0.

Family and domain databases

InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
IPR020435. TNFR_5.
[Graphical view]
PfamiPF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01922. TNFACTORR5.
SMARTiSM00208. TNFR. 3 hits.
[Graphical view]
PROSITEiPS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9JKE0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLPLPQLCAL WGCLLTAVHL GQCVTCSDKQ YLQGGECCDL CQPGNRLVSH
60 70 80 90 100
CTALEKTQCQ PCDSGEFSAH WNREIRCHQH RHCELNQGLQ VKKEGTAVSD
110 120 130 140 150
TVCTCKEGQH CASKECETCA QHRPCGPGFG VVQMATETTD TVCQPCPVGF
160
FSNGSSLFEK CHPWTSCED
Length:169
Mass (Da):18,525
Last modified:June 1, 2001 - v2
Checksum:iF199D91EFA224A26
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei169 – 1691Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF241231 mRNA. Translation: AAF43717.2.
UniGeneiRn.25180.

Genome annotation databases

UCSCiRGD:619830. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF241231 mRNA. Translation: AAF43717.2.
UniGeneiRn.25180.

3D structure databases

ProteinModelPortaliQ9JKE0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:619830. rat.

Organism-specific databases

RGDi619830. Cd40.

Phylogenomic databases

HOVERGENiHBG005117.
PhylomeDBiQ9JKE0.

Gene expression databases

GenevestigatoriQ9JKE0.

Family and domain databases

InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
IPR020435. TNFR_5.
[Graphical view]
PfamiPF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01922. TNFACTORR5.
SMARTiSM00208. TNFR. 3 hits.
[Graphical view]
PROSITEiPS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappaB and signal transducer and activation of transcription-1."
    Krzesz R., Wagner A.H., Cattaruzza M., Hecker M.
    FEBS Lett. 453:191-196(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WistarImported.
    Tissue: Smooth muscleImported.
  2. Krzesz R., Hecker M.
    Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WistarImported.
    Tissue: Smooth muscleImported.
  3. Gao D., Hecker M.
    Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WistarImported.
    Tissue: Smooth muscleImported.

Entry informationi

Entry nameiQ9JKE0_RAT
AccessioniPrimary (citable) accession number: Q9JKE0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.