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Protein
Submitted name:

Potassium channel TASK2

Gene

Kcnk5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular potassium ion transport Source: MGI
  • stabilization of membrane potential Source: GO_Central

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotationImported
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-MMU-5576886 Phase 4 - resting membrane potential

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel TASK2Imported
Submitted name:
Potassium channel, subfamily K, member 5Imported
Submitted name:
TASK2 potassium channelImported
Gene namesi
Name:Kcnk5Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1336175 Kcnk5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Transmembranei85 – 104HelicalSequence analysisAdd BLAST20
Transmembranei116 – 137HelicalSequence analysisAdd BLAST22
Transmembranei158 – 182HelicalSequence analysisAdd BLAST25
Transmembranei194 – 213HelicalSequence analysisAdd BLAST20
Transmembranei225 – 244HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000023243

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024011

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 137Ion_trans_2InterPro annotationAdd BLAST60
Domaini172 – 248Ion_trans_2InterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418 Eukaryota
COG1226 LUCA
GeneTreeiENSGT00760000118858
HOVERGENiHBG052236
KOiK04916
OMAiYFVELWI
OrthoDBiEOG091G058Z
TreeFamiTF313947

Family and domain databases

InterProiView protein in InterPro
IPR003280 2pore_dom_K_chnl
IPR003092 2pore_dom_K_chnl_TASK
IPR013099 K_chnl_dom
PfamiView protein in Pfam
PF07885 Ion_trans_2, 2 hits
PRINTSiPR01333 2POREKCHANEL
PR01095 TASKCHANNEL

Sequencei

Sequence statusi: Complete.

Q9JK62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDRGPLLTS AIIFYLAIGA AIFEVLEEPH WKEAKKNYYT QKLHLLKEFP
60 70 80 90 100
CLSQEGLDKI LQVVSDAADQ GVAITGNQTF NNWNWPNAMI FAATVITTIG
110 120 130 140 150
YGNVAPKTPA GRLFCVFYGL FGVPLCLTWI SALGKFFGGR AKRLGQFLTR
160 170 180 190 200
RGVSLRKAQI TCTAIFIVWG VLVHLVIPPF VFMVTEEWNY IEGLYYSFIT
210 220 230 240 250
ISTIGFGDFV AGVNPSANYH ALYRYFVELW IYLGLAWLSL FVNWKVSMFV
260 270 280 290 300
EVHKAIKKRR RRRKESFESS PHSRKALQMA GSTASKDVNI FSFLSKKEET
310 320 330 340 350
YNDLIKQIGK KAMKTSGGGE RVPGPGHGLG PQGDRLPTIP ASLAPLVVYS
360 370 380 390 400
KNRVPSLEEV SQTLKNKGHV SRPLGEEAGA QAPKDSYQTS EVFINQLDRI
410 420 430 440 450
SEEGEPWEAL DYHPLIFQNA NITFENEETG LSDEETSKSS VEDNLTSKEQ
460 470 480 490 500
PEQGPMAEAP LSSTGEFPSS DESTFTSTES ELSVPYEQLM NEYNKADNPR

GT
Length:502
Mass (Da):55,977
Last modified:October 1, 2000 - v1
Checksum:iE4C7E7CC71B44D95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126275 Genomic DNA No translation available.
AF259395 mRNA Translation: AAF68668.1
AF319542 mRNA Translation: AAG35065.1
BC034012 mRNA Translation: AAH34012.1
BC058164 mRNA Translation: AAH58164.1
AK085330 mRNA Translation: BAC39423.1
AK132172 mRNA Translation: BAE21010.1
RefSeqiNP_067517.1, NM_021542.4
UniGeneiMm.68998

Genome annotation databases

EnsembliENSMUST00000024011; ENSMUSP00000024011; ENSMUSG00000023243
GeneIDi16529
KEGGimmu:16529
UCSCiuc007siz.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9JK62_MOUSE
AccessioniPrimary (citable) accession number: Q9JK62
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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