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Protein
Submitted name:

Potassium channel TASK2

Gene

Kcnk5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular potassium ion transport Source: MGI
  • stabilization of membrane potential Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotationImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel TASK2Imported
Submitted name:
Potassium channel, subfamily K, member 5Imported
Submitted name:
Protein Kcnk5Imported
Submitted name:
TASK2 potassium channelImported
Gene namesi
Name:Kcnk5Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1336175. Kcnk5.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Transmembranei85 – 104HelicalSequence analysisAdd BLAST20
Transmembranei116 – 137HelicalSequence analysisAdd BLAST22
Transmembranei158 – 182HelicalSequence analysisAdd BLAST25
Transmembranei194 – 213HelicalSequence analysisAdd BLAST20
Transmembranei225 – 244HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000023243.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024011.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 137Ion_trans_2InterPro annotationAdd BLAST60
Domaini172 – 247Ion_trans_2InterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00760000118858.
HOVERGENiHBG052236.
KOiK04916.
OMAiEQLMNEY.
OrthoDBiEOG091G058Z.
TreeFamiTF313947.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR003092. 2pore_dom_K_chnl_TASK.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
PR01095. TASKCHANNEL.

Sequencei

Sequence statusi: Complete.

Q9JK62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDRGPLLTS AIIFYLAIGA AIFEVLEEPH WKEAKKNYYT QKLHLLKEFP
60 70 80 90 100
CLSQEGLDKI LQVVSDAADQ GVAITGNQTF NNWNWPNAMI FAATVITTIG
110 120 130 140 150
YGNVAPKTPA GRLFCVFYGL FGVPLCLTWI SALGKFFGGR AKRLGQFLTR
160 170 180 190 200
RGVSLRKAQI TCTAIFIVWG VLVHLVIPPF VFMVTEEWNY IEGLYYSFIT
210 220 230 240 250
ISTIGFGDFV AGVNPSANYH ALYRYFVELW IYLGLAWLSL FVNWKVSMFV
260 270 280 290 300
EVHKAIKKRR RRRKESFESS PHSRKALQMA GSTASKDVNI FSFLSKKEET
310 320 330 340 350
YNDLIKQIGK KAMKTSGGGE RVPGPGHGLG PQGDRLPTIP ASLAPLVVYS
360 370 380 390 400
KNRVPSLEEV SQTLKNKGHV SRPLGEEAGA QAPKDSYQTS EVFINQLDRI
410 420 430 440 450
SEEGEPWEAL DYHPLIFQNA NITFENEETG LSDEETSKSS VEDNLTSKEQ
460 470 480 490 500
PEQGPMAEAP LSSTGEFPSS DESTFTSTES ELSVPYEQLM NEYNKADNPR

GT
Length:502
Mass (Da):55,977
Last modified:October 1, 2000 - v1
Checksum:iE4C7E7CC71B44D95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126275 Genomic DNA. No translation available.
AF259395 mRNA. Translation: AAF68668.1.
AF319542 mRNA. Translation: AAG35065.1.
BC034012 mRNA. Translation: AAH34012.1.
BC058164 mRNA. Translation: AAH58164.1.
AK085330 mRNA. Translation: BAC39423.1.
AK132172 mRNA. Translation: BAE21010.1.
RefSeqiNP_067517.1. NM_021542.4.
UniGeneiMm.68998.

Genome annotation databases

EnsembliENSMUST00000024011; ENSMUSP00000024011; ENSMUSG00000023243.
GeneIDi16529.
KEGGimmu:16529.
UCSCiuc007siz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126275 Genomic DNA. No translation available.
AF259395 mRNA. Translation: AAF68668.1.
AF319542 mRNA. Translation: AAG35065.1.
BC034012 mRNA. Translation: AAH34012.1.
BC058164 mRNA. Translation: AAH58164.1.
AK085330 mRNA. Translation: BAC39423.1.
AK132172 mRNA. Translation: BAE21010.1.
RefSeqiNP_067517.1. NM_021542.4.
UniGeneiMm.68998.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024011.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000024011; ENSMUSP00000024011; ENSMUSG00000023243.
GeneIDi16529.
KEGGimmu:16529.
UCSCiuc007siz.1. mouse.

Organism-specific databases

CTDi8645.
MGIiMGI:1336175. Kcnk5.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00760000118858.
HOVERGENiHBG052236.
KOiK04916.
OMAiEQLMNEY.
OrthoDBiEOG091G058Z.
TreeFamiTF313947.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000023243.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR003092. 2pore_dom_K_chnl_TASK.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
PR01095. TASKCHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9JK62_MOUSE
AccessioniPrimary (citable) accession number: Q9JK62
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.