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Protein
Submitted name:

BAK protein

Gene

Bak1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • BH domain binding Source: RGD
  • chaperone binding Source: RGD
  • heat shock protein binding Source: RGD
  • protein heterodimerization activity Source: RGD
  • protein homodimerization activity Source: RGD

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-111452. Activation and oligomerization of BAK protein.

Names & Taxonomyi

Protein namesi
Submitted name:
BAK proteinImported
Submitted name:
BCL2-antagonist/killer 1, isoform CRA_bImported
Submitted name:
Bak1 proteinImported
Submitted name:
Protein Bak1Imported
Gene namesi
Name:Bak1Imported
Synonyms:BakImported
ORF Names:rCG_60911Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi621635. Bak1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei123 – 142HelicalSequence analysisAdd BLAST20
Transmembranei148 – 165HelicalSequence analysisAdd BLAST18
Transmembranei186 – 207HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

  • cytosol Source: RGD
  • endoplasmic reticulum Source: Ensembl
  • integral component of mitochondrial outer membrane Source: Ensembl
  • membrane Source: RGD
  • mitochondrial outer membrane Source: GO_Central
  • mitochondrion Source: HGNC
  • pore complex Source: HGNC
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000000485.

Interactioni

GO - Molecular functioni

  • BH domain binding Source: RGD
  • chaperone binding Source: RGD
  • heat shock protein binding Source: RGD
  • protein heterodimerization activity Source: RGD
  • protein homodimerization activity Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000000576.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4728. Eukaryota.
ENOG41123S0. LUCA.
GeneTreeiENSGT00530000062935.
HOGENOMiHOG000006521.
HOVERGENiHBG002674.
KOiK14021.
OMAiFQAMLQH.
OrthoDBiEOG091G0OCU.
TreeFamiTF315834.

Family and domain databases

InterProiIPR026308. BAK.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020726. Bcl2_BH2_motif_CS.
IPR020728. Bcl2_BH3_motif_CS.
IPR026298. Blc2_fam.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF41. PTHR11256:SF41. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01258. BH2. 1 hit.
PS01259. BH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JK59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGQGPGPP KGDCDEALSA SEQQVAQDTE EVFRSYVFYL HQQEQETQGA
60 70 80 90 100
AAPANPEMDN LSLEPNSVLG QVGRQLALIG DDINRRYDTE FQNLLEQLQP
110 120 130 140 150
TAGNAYELFT KIASSLFKSG ISWGRVVALL GFGYRLALYV YQRGLTGFLG
160 170 180 190 200
QVTCFLADII LHHYIARWIA QRGGWVAALS LRRDPILSVV VIFGVVLLGQ

FVVHRFFRS
Length:209
Mass (Da):23,153
Last modified:October 1, 2000 - v1
Checksum:i2493B814B1972421
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128962 Genomic DNA. No translation available.
AF259504 mRNA. Translation: AAF71760.1.
BC089784 mRNA. Translation: AAH89784.1.
CH473988 Genomic DNA. Translation: EDL96872.1.
RefSeqiNP_446264.1. NM_053812.1.
XP_006256163.1. XM_006256101.3.
UniGeneiRn.14598.

Genome annotation databases

EnsembliENSRNOT00000000576; ENSRNOP00000000576; ENSRNOG00000000485.
GeneIDi116502.
KEGGirno:116502.
UCSCiRGD:621635. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128962 Genomic DNA. No translation available.
AF259504 mRNA. Translation: AAF71760.1.
BC089784 mRNA. Translation: AAH89784.1.
CH473988 Genomic DNA. Translation: EDL96872.1.
RefSeqiNP_446264.1. NM_053812.1.
XP_006256163.1. XM_006256101.3.
UniGeneiRn.14598.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000000576.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000000576; ENSRNOP00000000576; ENSRNOG00000000485.
GeneIDi116502.
KEGGirno:116502.
UCSCiRGD:621635. rat.

Organism-specific databases

CTDi578.
RGDi621635. Bak1.

Phylogenomic databases

eggNOGiKOG4728. Eukaryota.
ENOG41123S0. LUCA.
GeneTreeiENSGT00530000062935.
HOGENOMiHOG000006521.
HOVERGENiHBG002674.
KOiK14021.
OMAiFQAMLQH.
OrthoDBiEOG091G0OCU.
TreeFamiTF315834.

Enzyme and pathway databases

ReactomeiR-RNO-111452. Activation and oligomerization of BAK protein.

Gene expression databases

BgeeiENSRNOG00000000485.

Family and domain databases

InterProiIPR026308. BAK.
IPR002475. Bcl2-like.
IPR020717. Bcl2_BH1_motif_CS.
IPR020726. Bcl2_BH2_motif_CS.
IPR020728. Bcl2_BH3_motif_CS.
IPR026298. Blc2_fam.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF41. PTHR11256:SF41. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PRINTSiPR01862. BCL2FAMILY.
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
PS01080. BH1. 1 hit.
PS01258. BH2. 1 hit.
PS01259. BH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9JK59_RAT
AccessioniPrimary (citable) accession number: Q9JK59
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.