Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Calcium transporting protein homolog

Gene

Trpv6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • calcium channel activity Source: MGI
  • calmodulin binding Source: MGI

GO - Biological processi

  • calcium ion homeostasis Source: MGI
  • calcium ion transmembrane transport Source: GOC
  • calcium ion transport Source: MGI
  • parathyroid hormone secretion Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotation

Keywords - Biological processi

Ion transport, Transport

Protein family/group databases

TCDBi1.A.4.2.6. the transient receptor potential ca(2+) channel (trp-cc) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium transporting protein homologImported
Gene namesi
Name:Trpv6Imported
Synonyms:CATImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1927259. Trpv6.

Subcellular locationi

GO - Cellular componenti

  • extracellular exosome Source: MGI
  • integral component of membrane Source: MGI
  • plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9JJJ0.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031902.

Structurei

3D structure databases

ProteinModelPortaliQ9JJJ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 5 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotationSAAS annotation, RepeatUniRule annotation, TransmembraneUniRule annotation

Phylogenomic databases

HOGENOMiHOG000234397.
HOVERGENiHBG061442.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR008344. TRPV5/TRPV6.
IPR008345. TRPV6_channel.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01765. ECACCHANNEL.
PR01766. ECACCHANNEL1.
SMARTiSM00248. ANK. 5 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
TIGRFAMsiTIGR00870. trp. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JJJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGWSLPKEKG LILCLWNKFC RWFHRQESWA QSRDEQNLLQ QKRIWESPLL
60 70 80 90 100
LAAKENDVQA LSKLLKFEGC EVHQRGAMGE TALHIAALYD NLEAAMVLME
110 120 130 140 150
AAPELVFEPM TSELYEGQTA LHMAVINQNV NLVRALLARR ASVSARATGS
160 170 180 190 200
VFTTGPYKPH YYGEHPLSFA ACVGSEGDGR LLIEHGADIR AQGLSGKYEY
210 220 230 240 250
YNILILQPNK TFACQMYNLL LSYDGGDHLK SLELVPNNQG LTPFKLAGVE
260 270 280 290 300
GNIVMFQHLM QKRKHIQWTY GPLTSTLYDL TEIDSSGDDQ SLLELIVTTK
310 320 330 340 350
KREARQILDQ TPVKELVSLK WKRYGRPYFC VLGAIYVLYI ICFTMCCVYR
360 370 380 390 400
PLKPRITNRT NPRDNTLMQQ KLLQEAYVTP KDDLRLVGEL VSIVGAVIIL
410 420 430 440 450
LVEIPDIFRL GVTRFFGQTI LGGPFHVIII TYAFMVLVTM VMRLTNVDGE
460 470 480 490 500
VVPMSFARCW LVQCHDFARG FQMLGPFTLH DSRRLIFGDL NAIFCWLMAV
510 520 530 540 550
VILGFASAFY IIFQTEDPDE LGHFYDYPMA LFSTFELFLT IIDGPANYDV
560 570 580 590 600
DLPFMYSVTY AAFAIIATLL MLNLLIAMMG DTHWRVAHER DELWRAQVVA
610 620 630 640 650
TTVMLERKLP RCLWPRSGIC GREYGLGDRW FLRVEDRQDL NRQRIRRYAQ
660 670 680 690 700
AFQQQDGLYS EDLEKDSGEK LETARPFGAY LSFPTPSVSR STSRSSTNWE
710 720
RLRQGALRKD LRGIINRGLE DGEGWEYQI
Length:729
Mass (Da):83,394
Last modified:October 1, 2000 - v1
Checksum:i6A3980E46B837618
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB037373 mRNA. Translation: BAA99538.1.
UniGeneiMm.296889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB037373 mRNA. Translation: BAA99538.1.
UniGeneiMm.296889.

3D structure databases

ProteinModelPortaliQ9JJJ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031902.

Protein family/group databases

TCDBi1.A.4.2.6. the transient receptor potential ca(2+) channel (trp-cc) family.

Proteomic databases

PRIDEiQ9JJJ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1927259. Trpv6.

Phylogenomic databases

HOGENOMiHOG000234397.
HOVERGENiHBG061442.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR008344. TRPV5/TRPV6.
IPR008345. TRPV6_channel.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01765. ECACCHANNEL.
PR01766. ECACCHANNEL1.
SMARTiSM00248. ANK. 5 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
TIGRFAMsiTIGR00870. trp. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Electrophysiologic characteristics of the Ca permeable channels, ECaC and CAT, in the kidney."
    Suzuki M.
    Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ9JJJ0_MOUSE
AccessioniPrimary (citable) accession number: Q9JJJ0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: June 24, 2015
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.