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Q9JJE4 (PAQR4_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Progestin and adipoQ receptor family member 4
Alternative name(s):
Progestin and adipoQ receptor family member IV
Gene names
Name:Paqr4
ORF Names:MNCb-0914
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the ADIPOR family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionReceptor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionreceptor activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 273273Progestin and adipoQ receptor family member 4
PRO_0000218849

Regions

Transmembrane52 – 7221Helical; Potential
Transmembrane79 – 9921Helical; Potential
Transmembrane115 – 13521Helical; Potential
Transmembrane185 – 20521Helical; Potential
Transmembrane245 – 26521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9JJE4 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 2D7568D439C351FD

FASTA27329,215
        10         20         30         40         50         60 
MAFLTGPRLL DWASSPPHLQ FNKFVLTGYR PASSGSGCLR SLFYLHNELG NIYTHGLALL 

        70         80         90        100        110        120 
GFLVLVPMTM PWSQLGKDGW LGGTHCVACL VPPAASVLYH LFMCHQGGSP VYTRLLALDM 

       130        140        150        160        170        180 
CGVCLVNTLG ALPIIHCTLA CRPWLRPAAL MGYTALSGVA GWRALTAPST SARLRAFGWQ 

       190        200        210        220        230        240 
AGARLLVFGA RGVGLGSGAP GSLPCYLRMD ALALLGGLVN VARLPERWGP GRFDYWGNSH 

       250        260        270 
QIMHLLSVGS ILQLHAGVVP DLLWAAHHAC PPD 

« Hide

References

« Hide 'large scale' references
[1]"PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif."
Tang Y.T., Hu T., Arterburn M., Boyle B., Bright J.M., Emtage P.C., Funk W.D.
J. Mol. Evol. 61:372-380(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: C57BL/6J.
[2]"Isolation of full-length cDNA clones from mouse brain cDNA library made by oligo-capping method."
Osada N., Kusuda J., Tanuma R., Ito A., Hirata M., Sugano S., Hashimoto K.
Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Brain.
[3]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Bone marrow, Brain cortex, Cecum, Cerebellum and Retina.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Eye and Liver.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY424293 mRNA. Translation: AAR08381.1.
AB041564 mRNA. Translation: BAA95048.1.
AK005142 mRNA. Translation: BAB23839.1.
AK033625 mRNA. Translation: BAC28398.1.
AK044092 mRNA. Translation: BAC31770.1.
AK044486 mRNA. Translation: BAC31947.1.
AK152676 mRNA. Translation: BAE31408.1.
BC011185 mRNA. Translation: AAH11185.1.
BC026921 mRNA. Translation: AAH26921.1.
RefSeqNP_076313.1. NM_023824.3.
UniGeneMm.491253.

3D structure databases

ProteinModelPortalQ9JJE4.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9JJE4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000024702; ENSMUSP00000024702; ENSMUSG00000023909.
GeneID76498.
KEGGmmu:76498.
UCSCuc008atb.1. mouse.

Organism-specific databases

CTD124222.
MGIMGI:1923748. Paqr4.

Phylogenomic databases

eggNOGCOG1272.
GeneTreeENSGT00530000062926.
HOGENOMHOG000006893.
HOVERGENHBG053505.
InParanoidQ9JJE4.
OMACHQGGSP.
OrthoDBEOG7PK905.
PhylomeDBQ9JJE4.
TreeFamTF323692.

Gene expression databases

BgeeQ9JJE4.
CleanExMM_PAQR4.
GenevestigatorQ9JJE4.

Family and domain databases

InterProIPR004254. HlyIII-related.
[Graphical view]
PANTHERPTHR20855. PTHR20855. 1 hit.
PfamPF03006. HlyIII. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio345258.
PROQ9JJE4.
SOURCESearch...

Entry information

Entry namePAQR4_MOUSE
AccessionPrimary (citable) accession number: Q9JJE4
Secondary accession number(s): Q3U7G1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot