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Q9JJE4

- PAQR4_MOUSE

UniProt

Q9JJE4 - PAQR4_MOUSE

Protein

Progestin and adipoQ receptor family member 4

Gene

Paqr4

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. receptor activity Source: RefGenome

    Keywords - Molecular functioni

    Receptor

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Progestin and adipoQ receptor family member 4
    Alternative name(s):
    Progestin and adipoQ receptor family member IV
    Gene namesi
    Name:Paqr4
    ORF Names:MNCb-0914
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1923748. Paqr4.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 273273Progestin and adipoQ receptor family member 4PRO_0000218849Add
    BLAST

    Proteomic databases

    PRIDEiQ9JJE4.

    Expressioni

    Gene expression databases

    BgeeiQ9JJE4.
    CleanExiMM_PAQR4.
    GenevestigatoriQ9JJE4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9JJE4.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei52 – 7221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei79 – 9921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei115 – 13521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei185 – 20521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei245 – 26521HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ADIPOR family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1272.
    GeneTreeiENSGT00530000062926.
    HOGENOMiHOG000006893.
    HOVERGENiHBG053505.
    InParanoidiQ9JJE4.
    OMAiCHQGGSP.
    OrthoDBiEOG7PK905.
    PhylomeDBiQ9JJE4.
    TreeFamiTF323692.

    Family and domain databases

    InterProiIPR004254. HlyIII-related.
    [Graphical view]
    PANTHERiPTHR20855. PTHR20855. 1 hit.
    PfamiPF03006. HlyIII. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9JJE4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAFLTGPRLL DWASSPPHLQ FNKFVLTGYR PASSGSGCLR SLFYLHNELG    50
    NIYTHGLALL GFLVLVPMTM PWSQLGKDGW LGGTHCVACL VPPAASVLYH 100
    LFMCHQGGSP VYTRLLALDM CGVCLVNTLG ALPIIHCTLA CRPWLRPAAL 150
    MGYTALSGVA GWRALTAPST SARLRAFGWQ AGARLLVFGA RGVGLGSGAP 200
    GSLPCYLRMD ALALLGGLVN VARLPERWGP GRFDYWGNSH QIMHLLSVGS 250
    ILQLHAGVVP DLLWAAHHAC PPD 273
    Length:273
    Mass (Da):29,215
    Last modified:October 1, 2000 - v1
    Checksum:i2D7568D439C351FD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY424293 mRNA. Translation: AAR08381.1.
    AB041564 mRNA. Translation: BAA95048.1.
    AK005142 mRNA. Translation: BAB23839.1.
    AK033625 mRNA. Translation: BAC28398.1.
    AK044092 mRNA. Translation: BAC31770.1.
    AK044486 mRNA. Translation: BAC31947.1.
    AK152676 mRNA. Translation: BAE31408.1.
    BC011185 mRNA. Translation: AAH11185.1.
    BC026921 mRNA. Translation: AAH26921.1.
    CCDSiCCDS28461.1.
    RefSeqiNP_076313.1. NM_023824.3.
    UniGeneiMm.491253.

    Genome annotation databases

    EnsembliENSMUST00000024702; ENSMUSP00000024702; ENSMUSG00000023909.
    GeneIDi76498.
    KEGGimmu:76498.
    UCSCiuc008atb.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY424293 mRNA. Translation: AAR08381.1 .
    AB041564 mRNA. Translation: BAA95048.1 .
    AK005142 mRNA. Translation: BAB23839.1 .
    AK033625 mRNA. Translation: BAC28398.1 .
    AK044092 mRNA. Translation: BAC31770.1 .
    AK044486 mRNA. Translation: BAC31947.1 .
    AK152676 mRNA. Translation: BAE31408.1 .
    BC011185 mRNA. Translation: AAH11185.1 .
    BC026921 mRNA. Translation: AAH26921.1 .
    CCDSi CCDS28461.1.
    RefSeqi NP_076313.1. NM_023824.3.
    UniGenei Mm.491253.

    3D structure databases

    ProteinModelPortali Q9JJE4.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9JJE4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000024702 ; ENSMUSP00000024702 ; ENSMUSG00000023909 .
    GeneIDi 76498.
    KEGGi mmu:76498.
    UCSCi uc008atb.1. mouse.

    Organism-specific databases

    CTDi 124222.
    MGIi MGI:1923748. Paqr4.

    Phylogenomic databases

    eggNOGi COG1272.
    GeneTreei ENSGT00530000062926.
    HOGENOMi HOG000006893.
    HOVERGENi HBG053505.
    InParanoidi Q9JJE4.
    OMAi CHQGGSP.
    OrthoDBi EOG7PK905.
    PhylomeDBi Q9JJE4.
    TreeFami TF323692.

    Miscellaneous databases

    NextBioi 345258.
    PROi Q9JJE4.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9JJE4.
    CleanExi MM_PAQR4.
    Genevestigatori Q9JJE4.

    Family and domain databases

    InterProi IPR004254. HlyIII-related.
    [Graphical view ]
    PANTHERi PTHR20855. PTHR20855. 1 hit.
    Pfami PF03006. HlyIII. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif."
      Tang Y.T., Hu T., Arterburn M., Boyle B., Bright J.M., Emtage P.C., Funk W.D.
      J. Mol. Evol. 61:372-380(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: C57BL/6J.
    2. "Isolation of full-length cDNA clones from mouse brain cDNA library made by oligo-capping method."
      Osada N., Kusuda J., Tanuma R., Ito A., Hirata M., Sugano S., Hashimoto K.
      Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Brain.
    3. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Bone marrow, Brain cortex, Cecum, Cerebellum and Retina.
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Eye and Liver.

    Entry informationi

    Entry nameiPAQR4_MOUSE
    AccessioniPrimary (citable) accession number: Q9JJE4
    Secondary accession number(s): Q3U7G1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 31, 2004
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3