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Protein

Ribosome production factor 2 homolog

Gene

Rpf2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome production factor 2 homolog
Alternative name(s):
Brix domain-containing protein 1
Ribosome biogenesis protein RPF2 homolog
Gene namesi
Name:Rpf2
Synonyms:Bxdc1
ORF Names:MNCb-4285
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1914489. Rpf2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001202241 – 306Ribosome production factor 2 homologAdd BLAST306

Proteomic databases

EPDiQ9JJ80.
MaxQBiQ9JJ80.
PaxDbiQ9JJ80.
PeptideAtlasiQ9JJ80.
PRIDEiQ9JJ80.

PTM databases

PhosphoSitePlusiQ9JJ80.

Expressioni

Gene expression databases

BgeeiENSMUSG00000038510.
CleanExiMM_BXDC1.
ExpressionAtlasiQ9JJ80. baseline and differential.
GenevisibleiQ9JJ80. MM.

Interactioni

Protein-protein interaction databases

BioGridi212039. 1 interactor.
IntActiQ9JJ80. 2 interactors.
MINTiMINT-4089446.
STRINGi10090.ENSMUSP00000035456.

Structurei

3D structure databases

ProteinModelPortaliQ9JJ80.
SMRiQ9JJ80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 234BrixPROSITE-ProRule annotationAdd BLAST204

Sequence similaritiesi

Belongs to the RPF2 family.Curated
Contains 1 Brix domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3031. Eukaryota.
COG5106. LUCA.
GeneTreeiENSGT00390000007279.
HOGENOMiHOG000157782.
HOVERGENiHBG050749.
InParanoidiQ9JJ80.
KOiK14847.
OMAiMRQPLAK.
OrthoDBiEOG091G0EYG.
PhylomeDBiQ9JJ80.

Family and domain databases

InterProiIPR007109. Brix.
[Graphical view]
PfamiPF04427. Brix. 1 hit.
[Graphical view]
SMARTiSM00879. Brix. 1 hit.
[Graphical view]
PROSITEiPS50833. BRIX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JJ80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDALDKVLKP KTKRAKRFLE KREPKLTENI KNAMLIKGGN ANATVTQVLR
60 70 80 90 100
DMYALKKPYG VLYKKKNITR PFEDQTSLEF FSKKSDCSLF MFGSHNKKRP
110 120 130 140 150
NNLVIGRMYD YHVLDMIELG IEKFVSLKDI KTSKCPEGTK PMLIFAGDDF
160 170 180 190 200
DVTEDFRRLK NLLIDFFRGP TVSNVRLAGL EYVLHFTALN GKVYFRSYKL
210 220 230 240 250
LLKKSGCRTP RIELEEMGPS LDLVMRRTHL ASDDLYKLSM KVPKALKPKK
260 270 280 290 300
RKNISQDTFG TTFGRIHMQK QDLSKLQTRK MKGLKKRPAE NGVDDQGKKS

KRIKKN
Length:306
Mass (Da):35,364
Last modified:September 26, 2001 - v2
Checksum:iCF732DBD515794AB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti8L → R in BAA95117 (Ref. 1) Curated1
Sequence conflicti79E → G in BAB28829 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041810 mRNA. Translation: BAA95117.1.
AK010776 mRNA. Translation: BAB27175.1.
AK011644 mRNA. No translation available.
AK012188 mRNA. Translation: BAB28087.1.
AK012641 mRNA. Translation: BAB28375.1.
AK013395 mRNA. Translation: BAB28829.1.
AK017678 mRNA. Translation: BAB30868.1.
AK020030 mRNA. Translation: BAB31973.1.
CCDSiCCDS59543.1.
RefSeqiNP_001036021.1. NM_001042556.1.
NP_075812.3. NM_023323.3.
UniGeneiMm.11480.

Genome annotation databases

EnsembliENSMUST00000183309; ENSMUSP00000138581; ENSMUSG00000038510.
GeneIDi67239.
KEGGimmu:67239.
UCSCiuc007ewo.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041810 mRNA. Translation: BAA95117.1.
AK010776 mRNA. Translation: BAB27175.1.
AK011644 mRNA. No translation available.
AK012188 mRNA. Translation: BAB28087.1.
AK012641 mRNA. Translation: BAB28375.1.
AK013395 mRNA. Translation: BAB28829.1.
AK017678 mRNA. Translation: BAB30868.1.
AK020030 mRNA. Translation: BAB31973.1.
CCDSiCCDS59543.1.
RefSeqiNP_001036021.1. NM_001042556.1.
NP_075812.3. NM_023323.3.
UniGeneiMm.11480.

3D structure databases

ProteinModelPortaliQ9JJ80.
SMRiQ9JJ80.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212039. 1 interactor.
IntActiQ9JJ80. 2 interactors.
MINTiMINT-4089446.
STRINGi10090.ENSMUSP00000035456.

PTM databases

PhosphoSitePlusiQ9JJ80.

Proteomic databases

EPDiQ9JJ80.
MaxQBiQ9JJ80.
PaxDbiQ9JJ80.
PeptideAtlasiQ9JJ80.
PRIDEiQ9JJ80.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000183309; ENSMUSP00000138581; ENSMUSG00000038510.
GeneIDi67239.
KEGGimmu:67239.
UCSCiuc007ewo.1. mouse.

Organism-specific databases

CTDi84154.
MGIiMGI:1914489. Rpf2.

Phylogenomic databases

eggNOGiKOG3031. Eukaryota.
COG5106. LUCA.
GeneTreeiENSGT00390000007279.
HOGENOMiHOG000157782.
HOVERGENiHBG050749.
InParanoidiQ9JJ80.
KOiK14847.
OMAiMRQPLAK.
OrthoDBiEOG091G0EYG.
PhylomeDBiQ9JJ80.

Miscellaneous databases

PROiQ9JJ80.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038510.
CleanExiMM_BXDC1.
ExpressionAtlasiQ9JJ80. baseline and differential.
GenevisibleiQ9JJ80. MM.

Family and domain databases

InterProiIPR007109. Brix.
[Graphical view]
PfamiPF04427. Brix. 1 hit.
[Graphical view]
SMARTiSM00879. Brix. 1 hit.
[Graphical view]
PROSITEiPS50833. BRIX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPF2_MOUSE
AccessioniPrimary (citable) accession number: Q9JJ80
Secondary accession number(s): Q8R3K6
, Q9CQ34, Q9CSY9, Q9CYR9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: September 26, 2001
Last modified: November 2, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.