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Protein
Submitted name:

Activator protein 4

Gene

Tfap4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Activator protein 4Imported
Submitted name:
Protein Tfap4Imported
Submitted name:
Transcription factor AP4Imported
Gene namesi
Name:Tfap4Imported
Synonyms:Ap4Imported, Tcfap4Imported
ORF Names:mCG_128721Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:103239. Tfap4.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: UniProtKB
  • transcriptional repressor complex Source: UniProtKB
Complete GO annotation...

PTM / Processingi

PTM databases

PhosphoSiteiQ9JIZ5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000005718.

Interactioni

GO - Molecular functioni

  • histone deacetylase binding Source: UniProtKB
  • protein homodimerization activity Source: MGI

Protein-protein interaction databases

DIPiDIP-59708N.
STRINGi10090.ENSMUSP00000005862.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 9952BHLH (basic helix-loop-helix)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili148 – 18235Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0561. Eukaryota.
ENOG4111JPE. LUCA.
GeneTreeiENSGT00390000015189.
HOGENOMiHOG000294087.
HOVERGENiHBG061473.
KOiK09108.
OMAiHHVNVVT.
OrthoDBiEOG091G194I.
TreeFamiTF316489.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JIZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYFMVPTQK VPSLQHFRKT EKEVIGGLCS LANIPLTPET QRDQERRIRR
60 70 80 90 100
EIANSNERRR MQSINAGFQS LKTLIPHTDG EKLSKAAILQ QTAEYIFSLE
110 120 130 140 150
QEKTRLLQQN TQLKRFIQEL SGSSPKRRRA EDKDEGIGSP DIWEDEKAED
160 170 180 190 200
LRREMIELRQ QLDKERSVRM MLEEQVRSLE AHMYPEKLKV IAQQVQLQQQ
210 220 230 240 250
QEQVRLLHQE KLEREQQHLR TQLLPPPAPT HHPTVIVPAP APPSSHHINV
260 270 280 290 300
VTMGPSSVIN SVSTSRQNLD TIVQAIQHIE GTQDKQELEE EQRRAVIVKS
310 320 330
VRSCPDAHTS DTASDSEASD SDAMDQSREE PLGDGELP
Length:338
Mass (Da):38,727
Last modified:October 1, 2000 - v1
Checksum:iFDCF2C4FBD38D29B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC157597 Genomic DNA. No translation available.
AF161262 mRNA. Translation: AAF80448.1.
BC047270 mRNA. Translation: AAH47270.1.
BC054777 mRNA. Translation: AAH54777.1.
AK166424 mRNA. Translation: BAE38767.1.
CH466521 Genomic DNA. Translation: EDK97233.1.
RefSeqiNP_112459.1. NM_031182.2.
UniGeneiMm.273210.

Genome annotation databases

EnsembliENSMUST00000005862; ENSMUSP00000005862; ENSMUSG00000005718.
GeneIDi83383.
KEGGimmu:83383.
UCSCiuc007xzv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC157597 Genomic DNA. No translation available.
AF161262 mRNA. Translation: AAF80448.1.
BC047270 mRNA. Translation: AAH47270.1.
BC054777 mRNA. Translation: AAH54777.1.
AK166424 mRNA. Translation: BAE38767.1.
CH466521 Genomic DNA. Translation: EDK97233.1.
RefSeqiNP_112459.1. NM_031182.2.
UniGeneiMm.273210.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-59708N.
STRINGi10090.ENSMUSP00000005862.

PTM databases

PhosphoSiteiQ9JIZ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000005862; ENSMUSP00000005862; ENSMUSG00000005718.
GeneIDi83383.
KEGGimmu:83383.
UCSCiuc007xzv.1. mouse.

Organism-specific databases

CTDi7023.
MGIiMGI:103239. Tfap4.

Phylogenomic databases

eggNOGiKOG0561. Eukaryota.
ENOG4111JPE. LUCA.
GeneTreeiENSGT00390000015189.
HOGENOMiHOG000294087.
HOVERGENiHBG061473.
KOiK09108.
OMAiHHVNVVT.
OrthoDBiEOG091G194I.
TreeFamiTF316489.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000005718.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9JIZ5_MOUSE
AccessioniPrimary (citable) accession number: Q9JIZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 127 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.