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Q9JIG7 (CCD22_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Coiled-coil domain-containing protein 22
Gene names
Name:Ccdc22
Synonyms:DXImx40e
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length627 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with CPNE1 and CPNE4. Ref.5

Sequence similarities

Belongs to the CCDC22 family.

Ontologies

Keywords
   DomainCoiled coil
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 627627Coiled-coil domain-containing protein 22
PRO_0000076200

Regions

Coiled coil448 – 53588 Potential

Amino acid modifications

Modified residue4101Phosphoserine By similarity

Experimental info

Sequence conflict1171D → N in BAC30390. Ref.2
Sequence conflict5291S → F in BAC30390. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9JIG7 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 3710732B4CD90A2E

FASTA62770,844
        10         20         30         40         50         60 
MEEADRILIH SLRQAGTAVP PEVQTLRAFT TELVVEAVVR CLRVINPDVG SGLSHLLPPA 

        70         80         90        100        110        120 
MSARFRLAMS LAQACMDLGY PLELGYQNFL YPSEPDLRDL LLFLAERLPS DASEDADQPA 

       130        140        150        160        170        180 
GDSAIFLRAI GSQIRDQLAL PWVPPLLRTP KVQRLQGSAL QQPFHSSRLV LPELNSSGEL 

       190        200        210        220        230        240 
WEFQASPLLL PAPTQVPQLQ GRAASLLEHH ASQLCQHVNR DCPGDEDRVR WASRVPSQED 

       250        260        270        280        290        300 
SRAPQQRLHK QLIEHLRQSW GPLGAPTQVR DLGEMLQTWG ARAMTGVPKG SRFTHSEKFT 

       310        320        330        340        350        360 
FHLEPQVQAA QVADVPATSQ RLEQDTRAAQ EQELESLREQ LASVNHNIEE VEADMKTLGI 

       370        380        390        400        410        420 
NLVQVETECR QSELSVAEQE QALRLKSRTV ELLPDGAANL AKLQLVVESS AQRLIHLASQ 

       430        440        450        460        470        480 
WEKHRVPLLA EYRHLRRLQD CRELESSRRL AEIQELHHSV RAAAEEARRK EEVYKQLVSE 

       490        500        510        520        530        540 
LETLPKDVSR LAYTQRILEI VGNIRKQKEE ITKILSDTKE LQKEINSLSG KLDRTFAVTD 

       550        560        570        580        590        600 
ELVFKDAKKD DAVRKAYKYL AALHENCSQL IQTIEDTGTI MREVRDLEEQ IETEMGKKTL 

       610        620 
SNLEKICEDY RALRQENAGL LGRVREA

« Hide

References

« Hide 'large scale' references
[1]"A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation."
Means G.D., Toy D.Y., Baum P.R., Derry J.M.J.
Genomics 65:213-223(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Spinal cord.
[3]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Salivary gland.
[5]"Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif."
Tomsig J.L., Snyder S.L., Creutz C.E.
J. Biol. Chem. 278:10048-10054(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH CPNE1 AND CPNE4.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF229637 mRNA. Translation: AAF66951.1.
AK010536 mRNA. Translation: BAB27013.1.
AK039573 mRNA. Translation: BAC30390.1.
AL672231 Genomic DNA. Translation: CAM25951.1.
BC011195 mRNA. Translation: AAH11195.1.
IPIIPI00331244.
RefSeqNP_613069.3. NM_138603.3.
UniGeneMm.288192.

3D structure databases

ProteinModelPortalQ9JIG7.
ModBaseSearch...

Protein-protein interaction databases

MINTMINT-1865494.

PTM databases

PhosphoSiteQ9JIG7.

Proteomic databases

PaxDbQ9JIG7.
PRIDEQ9JIG7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000033483; ENSMUSP00000033483; ENSMUSG00000031143.
GeneID54638.
KEGGmmu:54638.
UCSCuc009sln.1. mouse.

Organism-specific databases

CTD28952.
MGIMGI:1859608. Ccdc22.

Phylogenomic databases

eggNOGNOG253647.
GeneTreeENSGT00390000003809.
HOGENOMHOG000039965.
HOVERGENHBG053063.
InParanoidB1AVA1.
OrthoDBEOG43JC4C.

Gene expression databases

BgeeQ9JIG7.
CleanExMM_CCDC22.
GenevestigatorQ9JIG7.
GermOnlineENSMUSG00000031143. Mus musculus.

Family and domain databases

InterProIPR008530. DUF812.
[Graphical view]
PANTHERPTHR15668. PTHR15668. 1 hit.
PfamPF05667. DUF812. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSCCDC22. mouse.
NextBio311476.
SOURCESearch...

Entry information

Entry nameCCD22_MOUSE
AccessionPrimary (citable) accession number: Q9JIG7
Secondary accession number(s): B1AVA1, Q8BYH4
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: October 1, 2000
Last modified: May 29, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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