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Q9JID2 (GNA11_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Guanine nucleotide-binding protein subunit alpha-11
Short name=G alpha-11
Short name=G-protein subunit alpha-11
Gene names
Name:Gna11
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Subunit structure

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

Subcellular location

Cell membrane; Lipid-anchor By similarity.

Sequence similarities

Belongs to the G-alpha family. G(q) subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Guanine nucleotide-binding protein subunit alpha-11
PRO_0000203748

Regions

Nucleotide binding46 – 538GTP By similarity
Nucleotide binding180 – 1867GTP By similarity
Nucleotide binding205 – 2095GTP By similarity
Nucleotide binding274 – 2774GTP By similarity

Sites

Metal binding531Magnesium By similarity
Metal binding1861Magnesium By similarity
Binding site3311GTP; via amide nitrogen By similarity

Amino acid modifications

Lipidation91S-palmitoyl cysteine By similarity
Lipidation101S-palmitoyl cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9JID2 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: B4CD057E9FC7092A

FASTA35942,026
        10         20         30         40         50         60 
MTLESMIACC LSDEVKESKR INAEIEKQLR RDKRDARREL KLLLLGTGES GKSTFIKQMR 

        70         80         90        100        110        120 
IIHGAGYSEE DKRGFTKLVY QNIFTAMQAV VRAMDTLKIR YKYEQNKANA LLIREVDVEK 

       130        140        150        160        170        180 
VTTFEHQYVN AIKTLWSDPG VQECYDRRRE FQLSDSAKYY LTDVDRIATV GYLPTQQDVL 

       190        200        210        220        230        240 
RVRVPTTGII EYPFDLENII FRMVDVGGQR SERRKWIHCF ENVTSIMFLV ALSEYDQVLV 

       250        260        270        280        290        300 
ESDNENRMEE SKALFRTIIT YPWFQHSSVI LFLNKKDLLE DKILHSHLVD YFPEFDGPQR 

       310        320        330        340        350 
DAQAAREFIL KMFVDLNPDS DKIIYSHFTC ATDTENIRFV FAAVKDTILQ LNLKEYNLV

« Hide

References

[1]"Rattus norvegicus guanine nucleotide binding protein alpha 11 subunit (G11)."
Strotmann R.
Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF239674 mRNA. Translation: AAF81690.1.
IPIIPI00200437.
RefSeqNP_112295.1. NM_031033.1.
UniGeneRn.21925.

3D structure databases

ProteinModelPortalQ9JID2.
SMRQ9JID2. Positions 36-358.
ModBaseSearch...

Protein-protein interaction databases

MINTMINT-4569256.

PTM databases

PhosphoSiteQ9JID2.

Proteomic databases

PaxDbQ9JID2.
PRIDEQ9JID2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID81662.
KEGGrno:81662.
UCSCRGD:619749. rat.

Organism-specific databases

CTD2767.
RGD619749. Gna11.

Phylogenomic databases

eggNOGNOG322962.
HOGENOMHOG000038729.
HOVERGENHBG063184.
InParanoidQ9JID2.
KOK04635.
OrthoDBEOG4S4PGD.

Gene expression databases

ArrayExpressQ9JID2.
GenevestigatorQ9JID2.
GermOnlineENSRNOG00000005446. Rattus norvegicus.

Family and domain databases

Gene3D1.10.400.10. 1 hit.
InterProIPR000654. Gprotein_alpha_Q.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR10218. PTHR10218. 1 hit.
PfamPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSPR00318. GPROTEINA.
PR00442. GPROTEINAQ.
SMARTSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
SSF47895. Transducn_insert. 1 hit.
ProtoNetSearch...

Other

NextBio615236.

Entry information

Entry nameGNA11_RAT
AccessionPrimary (citable) accession number: Q9JID2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: October 1, 2000
Last modified: May 29, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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