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Q9JIB3 (BIR1G_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Baculoviral IAP repeat-containing protein 1g
Alternative name(s):
Neuronal apoptosis inhibitory protein 7
Gene names
Name:Naip7
Synonyms:Birc1g
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length1402 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Prevents motor-neuron apoptosis induced by a variety of signals.

Sequence similarities

Contains 3 BIR repeats.

Contains 1 NACHT domain.

Ontologies

Keywords
   Biological processApoptosis
   DomainRepeat
   LigandATP-binding
Metal-binding
Nucleotide-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processapoptotic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from sequence or structural similarity. Source: UniProtKB

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14021402Baculoviral IAP repeat-containing protein 1g
PRO_0000122346

Regions

Repeat60 – 12768BIR 1
Repeat159 – 22769BIR 2
Repeat278 – 34568BIR 3
Domain464 – 759296NACHT

Sites

Metal binding3151Zinc By similarity
Metal binding3181Zinc By similarity
Metal binding3351Zinc By similarity
Metal binding3421Zinc By similarity
Binding site4761ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9JIB3 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: C1DFFBA359893E0D

FASTA1,402159,664
        10         20         30         40         50         60 
MAEHGESSED RISEIDYEFL AELSARFGMN LVQLAKSQEE EDHKERMKMK KGFNSQMRSE 

        70         80         90        100        110        120 
AKRLKTFESY DTFRSWTPQE MAAAGFYHTG VKLGVQCFCC SLILFGNSLR KLPIERHKKL 

       130        140        150        160        170        180 
RPECEFLQGK DVGNIGKYDI RVKSPEKMLR GGKARYHEEE ARLESFEDWP FYAHGTSPRV 

       190        200        210        220        230        240 
LSAAGFVFTG KRDTVQCFSC GGSLGNWEEG DDPWKEHAKW FPKCEFLQSK KSSEEIAQYI 

       250        260        270        280        290        300 
QGYEGFVHVT GEHFVKSWVR RELPMVSAYC NDSVFANEEL RMDMFKDWPQ ESPVGVEALV 

       310        320        330        340        350        360 
RAGFFYTGKK DIVRCFSCGG CLEKWAEGDD PMEDHIKFFP ECVFLQTLKS SAEVIPTLQS 

       370        380        390        400        410        420 
QYALPEATET TRESNHGDAA AVHSTVVDLG RSEAQWFQEA RSLSEQLRDT YTKTSFCHMN 

       430        440        450        460        470        480 
LPEVCSSLGT DHLLSCDVSI ISKHISQPVQ GALTIPEVFS NLSSVMCVEG EAGSGKTTFL 

       490        500        510        520        530        540 
KRIAFLWASG CCPLLYRFQL VFYLSLSSIT PDQGLDNIIC TQLLGAGGCI SEVCLSSSIQ 

       550        560        570        580        590        600 
QLQHQVLFLL DDYSGLASLP QALHTLITKN YLFRTCLLIA VHTNRVRDIR PYLGTSLEIQ 

       610        620        630        640        650        660 
EFPFYNTVFV LRKFFSHDII CVEKLIIYFS ENKDLQGVYK TPLFVAAVCN DWNQNASAQD 

       670        680        690        700        710        720 
DFQDVTLFHS YMQYLSLKYK ATAESLQATV SSCGQLALTG LFSSCFEFNS DDLAEAGVDE 

       730        740        750        760        770        780 
DVKLTTFLMS KFTAQRLRPV YRFLGPLFQE FLAAVRLTEL LSSDRQEDQD LGLYYLRQID 

       790        800        810        820        830        840 
SPLKAINSFN IFLYYVSSHS SSKAAPTVVS HLLQLVDEKE SLENMSENED YMKLHPQTFL 

       850        860        870        880        890        900 
WFQFVRGLWL VSPESFSSFV SEHLLRLALI FAYESNTVAE CSPFILQFLR GRTLALRVLN 

       910        920        930        940        950        960 
LEYFWDHPES LLLLRSLKVS INGNKMSSYV DYSFKTYFEN LQPPAINEEY TSAFEHVSEW 

       970        980        990       1000       1010       1020 
RRNFAQDEEI IKNYENIWPR ALPDISEGYW NLSPKPCKIP KLEVQVNNMG PADQALLQVL 

      1030       1040       1050       1060       1070       1080 
MEVFSASQSI EFHLFNSSGF LESIRPALEL SKASVTKCSM SRLELSRAEQ ELLLTLPALQ 

      1090       1100       1110       1120       1130       1140 
SLEVSETNQL PDQLFHNLHK FLGLKELCVR LDGKPDVLSV LPEEFLNLHH MEKLSIRTST 

      1150       1160       1170       1180       1190       1200 
ESDLSKLVKF IQNFPNLHVF HLKCDFLSNC ESLMTALASC KKLREIEFSG QCFEAMTFVN 

      1210       1220       1230       1240       1250       1260 
ILPNFVSLKI LSLKGQQFAD KETSEKFAQA LGSLRNLEEL LVPTGDGIHQ VAKLIVRQCL 

      1270       1280       1290       1300       1310       1320 
QLPCLRVLAF HDILDDESVI EIGAATSGSF QKLENLDISM NHKITEEGYR NFFQALDNLP 

      1330       1340       1350       1360       1370       1380 
NLQMLNICRN IPGRIQVQAT TVKALCHCVS RLPSLTRLGM LSWLLDEEDM KVINDVKERH 

      1390       1400 
PQSKRLTIFW KWIVPFSPVV LE

« Hide

References

[1]"Genomic sequence analysis of the mouse Naip gene array."
Endrizzi M.G., Hadinoto V., Growney J.D., Miller W., Dietrich W.F.
Genome Res. 10:1095-1102(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF242433 Genomic DNA. Translation: AAF82749.1.
IPIIPI00387264.
RefSeqNP_067520.1. NM_021545.1.
UniGeneMm.218759.

3D structure databases

ProteinModelPortalQ9JIB3.
SMRQ9JIB3. Positions 60-128, 140-244, 276-345, 1075-1139, 1179-1362.
ModBaseSearch...

Protein family/group databases

MEROPSI32.001.

PTM databases

PhosphoSiteQ9JIB3.

Proteomic databases

PRIDEQ9JIB3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID53880.
KEGGmmu:53880.
UCSCuc007rql.1. mouse.

Organism-specific databases

CTD53880.
MGIMGI:1858256. Naip7.

Phylogenomic databases

HOVERGENHBG050689.
InParanoidQ9JIB3.
KOK12807.

Gene expression databases

GenevestigatorQ9JIB3.
GermOnlineENSMUSG00000071203. Mus musculus.

Family and domain databases

Gene3D1.10.1170.10. 3 hits.
InterProIPR001370. BIR.
IPR007111. NACHT_NTPase.
[Graphical view]
PfamPF00653. BIR. 3 hits.
[Graphical view]
SMARTSM00238. BIR. 3 hits.
[Graphical view]
PROSITEPS01282. BIR_REPEAT_1. 2 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50837. NACHT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio310753.
SOURCESearch...

Entry information

Entry nameBIR1G_MOUSE
AccessionPrimary (citable) accession number: Q9JIB3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: October 1, 2000
Last modified: May 1, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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