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Q9JIB3

- BIR1G_MOUSE

UniProt

Q9JIB3 - BIR1G_MOUSE

Protein

Baculoviral IAP repeat-containing protein 1g

Gene

Naip7

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Prevents motor-neuron apoptosis induced by a variety of signals.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi315 – 3151ZincPROSITE-ProRule annotation
    Metal bindingi318 – 3181ZincPROSITE-ProRule annotation
    Metal bindingi335 – 3351ZincPROSITE-ProRule annotation
    Metal bindingi342 – 3421ZincPROSITE-ProRule annotation
    Binding sitei476 – 4761ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. apoptotic process Source: UniProtKB-KW

    Keywords - Biological processi

    Apoptosis

    Keywords - Ligandi

    ATP-binding, Metal-binding, Nucleotide-binding, Zinc

    Protein family/group databases

    MEROPSiI32.001.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Baculoviral IAP repeat-containing protein 1g
    Alternative name(s):
    Neuronal apoptosis inhibitory protein 7
    Gene namesi
    Name:Naip7
    Synonyms:Birc1g
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    Organism-specific databases

    MGIiMGI:1858256. Naip7.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 14021402Baculoviral IAP repeat-containing protein 1gPRO_0000122346Add
    BLAST

    Proteomic databases

    PRIDEiQ9JIB3.

    PTM databases

    PhosphoSiteiQ9JIB3.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9JIB3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9JIB3.
    SMRiQ9JIB3. Positions 60-128, 140-244, 276-345, 1071-1160, 1181-1219, 1288-1388.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati60 – 12768BIR 1Add
    BLAST
    Repeati159 – 22769BIR 2Add
    BLAST
    Repeati278 – 34568BIR 3Add
    BLAST
    Domaini464 – 759296NACHTPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 3 BIR repeats.PROSITE-ProRule annotation
    Contains 1 NACHT domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    HOVERGENiHBG050689.
    InParanoidiQ9JIB3.
    KOiK12807.

    Family and domain databases

    Gene3Di1.10.1170.10. 3 hits.
    InterProiIPR001370. BIR.
    IPR007111. NACHT_NTPase.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00653. BIR. 3 hits.
    [Graphical view]
    SMARTiSM00238. BIR. 3 hits.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS01282. BIR_REPEAT_1. 2 hits.
    PS50143. BIR_REPEAT_2. 3 hits.
    PS50837. NACHT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9JIB3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEHGESSED RISEIDYEFL AELSARFGMN LVQLAKSQEE EDHKERMKMK     50
    KGFNSQMRSE AKRLKTFESY DTFRSWTPQE MAAAGFYHTG VKLGVQCFCC 100
    SLILFGNSLR KLPIERHKKL RPECEFLQGK DVGNIGKYDI RVKSPEKMLR 150
    GGKARYHEEE ARLESFEDWP FYAHGTSPRV LSAAGFVFTG KRDTVQCFSC 200
    GGSLGNWEEG DDPWKEHAKW FPKCEFLQSK KSSEEIAQYI QGYEGFVHVT 250
    GEHFVKSWVR RELPMVSAYC NDSVFANEEL RMDMFKDWPQ ESPVGVEALV 300
    RAGFFYTGKK DIVRCFSCGG CLEKWAEGDD PMEDHIKFFP ECVFLQTLKS 350
    SAEVIPTLQS QYALPEATET TRESNHGDAA AVHSTVVDLG RSEAQWFQEA 400
    RSLSEQLRDT YTKTSFCHMN LPEVCSSLGT DHLLSCDVSI ISKHISQPVQ 450
    GALTIPEVFS NLSSVMCVEG EAGSGKTTFL KRIAFLWASG CCPLLYRFQL 500
    VFYLSLSSIT PDQGLDNIIC TQLLGAGGCI SEVCLSSSIQ QLQHQVLFLL 550
    DDYSGLASLP QALHTLITKN YLFRTCLLIA VHTNRVRDIR PYLGTSLEIQ 600
    EFPFYNTVFV LRKFFSHDII CVEKLIIYFS ENKDLQGVYK TPLFVAAVCN 650
    DWNQNASAQD DFQDVTLFHS YMQYLSLKYK ATAESLQATV SSCGQLALTG 700
    LFSSCFEFNS DDLAEAGVDE DVKLTTFLMS KFTAQRLRPV YRFLGPLFQE 750
    FLAAVRLTEL LSSDRQEDQD LGLYYLRQID SPLKAINSFN IFLYYVSSHS 800
    SSKAAPTVVS HLLQLVDEKE SLENMSENED YMKLHPQTFL WFQFVRGLWL 850
    VSPESFSSFV SEHLLRLALI FAYESNTVAE CSPFILQFLR GRTLALRVLN 900
    LEYFWDHPES LLLLRSLKVS INGNKMSSYV DYSFKTYFEN LQPPAINEEY 950
    TSAFEHVSEW RRNFAQDEEI IKNYENIWPR ALPDISEGYW NLSPKPCKIP 1000
    KLEVQVNNMG PADQALLQVL MEVFSASQSI EFHLFNSSGF LESIRPALEL 1050
    SKASVTKCSM SRLELSRAEQ ELLLTLPALQ SLEVSETNQL PDQLFHNLHK 1100
    FLGLKELCVR LDGKPDVLSV LPEEFLNLHH MEKLSIRTST ESDLSKLVKF 1150
    IQNFPNLHVF HLKCDFLSNC ESLMTALASC KKLREIEFSG QCFEAMTFVN 1200
    ILPNFVSLKI LSLKGQQFAD KETSEKFAQA LGSLRNLEEL LVPTGDGIHQ 1250
    VAKLIVRQCL QLPCLRVLAF HDILDDESVI EIGAATSGSF QKLENLDISM 1300
    NHKITEEGYR NFFQALDNLP NLQMLNICRN IPGRIQVQAT TVKALCHCVS 1350
    RLPSLTRLGM LSWLLDEEDM KVINDVKERH PQSKRLTIFW KWIVPFSPVV 1400
    LE 1402
    Length:1,402
    Mass (Da):159,664
    Last modified:October 1, 2000 - v1
    Checksum:iC1DFFBA359893E0D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF242433 Genomic DNA. Translation: AAF82749.1.
    RefSeqiNP_067520.1. NM_021545.1.
    UniGeneiMm.218759.

    Genome annotation databases

    GeneIDi53880.
    KEGGimmu:53880.
    UCSCiuc011zdt.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF242433 Genomic DNA. Translation: AAF82749.1 .
    RefSeqi NP_067520.1. NM_021545.1.
    UniGenei Mm.218759.

    3D structure databases

    ProteinModelPortali Q9JIB3.
    SMRi Q9JIB3. Positions 60-128, 140-244, 276-345, 1071-1160, 1181-1219, 1288-1388.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I32.001.

    PTM databases

    PhosphoSitei Q9JIB3.

    Proteomic databases

    PRIDEi Q9JIB3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 53880.
    KEGGi mmu:53880.
    UCSCi uc011zdt.1. mouse.

    Organism-specific databases

    CTDi 53880.
    MGIi MGI:1858256. Naip7.

    Phylogenomic databases

    HOVERGENi HBG050689.
    InParanoidi Q9JIB3.
    KOi K12807.

    Miscellaneous databases

    NextBioi 310753.
    PROi Q9JIB3.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9JIB3.

    Family and domain databases

    Gene3Di 1.10.1170.10. 3 hits.
    InterProi IPR001370. BIR.
    IPR007111. NACHT_NTPase.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00653. BIR. 3 hits.
    [Graphical view ]
    SMARTi SM00238. BIR. 3 hits.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS01282. BIR_REPEAT_1. 2 hits.
    PS50143. BIR_REPEAT_2. 3 hits.
    PS50837. NACHT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiBIR1G_MOUSE
    AccessioniPrimary (citable) accession number: Q9JIB3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 24, 2001
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3