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Q9JIB3

- BIR1G_MOUSE

UniProt

Q9JIB3 - BIR1G_MOUSE

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Protein
Baculoviral IAP repeat-containing protein 1g
Gene
Naip7, Birc1g
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

Prevents motor-neuron apoptosis induced by a variety of signals.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi315 – 3151Zinc By similarity
Metal bindingi318 – 3181Zinc By similarity
Metal bindingi335 – 3351Zinc By similarity
Metal bindingi342 – 3421Zinc By similarity
Binding sitei476 – 4761ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. apoptotic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Apoptosis

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Protein family/group databases

MEROPSiI32.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Baculoviral IAP repeat-containing protein 1g
Alternative name(s):
Neuronal apoptosis inhibitory protein 7
Gene namesi
Name:Naip7
Synonyms:Birc1g
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:1858256. Naip7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14021402Baculoviral IAP repeat-containing protein 1g
PRO_0000122346Add
BLAST

Proteomic databases

PRIDEiQ9JIB3.

PTM databases

PhosphoSiteiQ9JIB3.

Expressioni

Gene expression databases

GenevestigatoriQ9JIB3.

Structurei

3D structure databases

ProteinModelPortaliQ9JIB3.
SMRiQ9JIB3. Positions 60-128, 140-244, 276-345, 1071-1160, 1181-1219, 1288-1388.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati60 – 12768BIR 1
Add
BLAST
Repeati159 – 22769BIR 2
Add
BLAST
Repeati278 – 34568BIR 3
Add
BLAST
Domaini464 – 759296NACHT
Add
BLAST

Sequence similaritiesi

Contains 3 BIR repeats.
Contains 1 NACHT domain.

Keywords - Domaini

Repeat

Phylogenomic databases

HOVERGENiHBG050689.
InParanoidiQ9JIB3.
KOiK12807.

Family and domain databases

Gene3Di1.10.1170.10. 3 hits.
InterProiIPR001370. BIR.
IPR007111. NACHT_NTPase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00653. BIR. 3 hits.
[Graphical view]
SMARTiSM00238. BIR. 3 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS01282. BIR_REPEAT_1. 2 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50837. NACHT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JIB3-1 [UniParc]FASTAAdd to Basket

« Hide

MAEHGESSED RISEIDYEFL AELSARFGMN LVQLAKSQEE EDHKERMKMK     50
KGFNSQMRSE AKRLKTFESY DTFRSWTPQE MAAAGFYHTG VKLGVQCFCC 100
SLILFGNSLR KLPIERHKKL RPECEFLQGK DVGNIGKYDI RVKSPEKMLR 150
GGKARYHEEE ARLESFEDWP FYAHGTSPRV LSAAGFVFTG KRDTVQCFSC 200
GGSLGNWEEG DDPWKEHAKW FPKCEFLQSK KSSEEIAQYI QGYEGFVHVT 250
GEHFVKSWVR RELPMVSAYC NDSVFANEEL RMDMFKDWPQ ESPVGVEALV 300
RAGFFYTGKK DIVRCFSCGG CLEKWAEGDD PMEDHIKFFP ECVFLQTLKS 350
SAEVIPTLQS QYALPEATET TRESNHGDAA AVHSTVVDLG RSEAQWFQEA 400
RSLSEQLRDT YTKTSFCHMN LPEVCSSLGT DHLLSCDVSI ISKHISQPVQ 450
GALTIPEVFS NLSSVMCVEG EAGSGKTTFL KRIAFLWASG CCPLLYRFQL 500
VFYLSLSSIT PDQGLDNIIC TQLLGAGGCI SEVCLSSSIQ QLQHQVLFLL 550
DDYSGLASLP QALHTLITKN YLFRTCLLIA VHTNRVRDIR PYLGTSLEIQ 600
EFPFYNTVFV LRKFFSHDII CVEKLIIYFS ENKDLQGVYK TPLFVAAVCN 650
DWNQNASAQD DFQDVTLFHS YMQYLSLKYK ATAESLQATV SSCGQLALTG 700
LFSSCFEFNS DDLAEAGVDE DVKLTTFLMS KFTAQRLRPV YRFLGPLFQE 750
FLAAVRLTEL LSSDRQEDQD LGLYYLRQID SPLKAINSFN IFLYYVSSHS 800
SSKAAPTVVS HLLQLVDEKE SLENMSENED YMKLHPQTFL WFQFVRGLWL 850
VSPESFSSFV SEHLLRLALI FAYESNTVAE CSPFILQFLR GRTLALRVLN 900
LEYFWDHPES LLLLRSLKVS INGNKMSSYV DYSFKTYFEN LQPPAINEEY 950
TSAFEHVSEW RRNFAQDEEI IKNYENIWPR ALPDISEGYW NLSPKPCKIP 1000
KLEVQVNNMG PADQALLQVL MEVFSASQSI EFHLFNSSGF LESIRPALEL 1050
SKASVTKCSM SRLELSRAEQ ELLLTLPALQ SLEVSETNQL PDQLFHNLHK 1100
FLGLKELCVR LDGKPDVLSV LPEEFLNLHH MEKLSIRTST ESDLSKLVKF 1150
IQNFPNLHVF HLKCDFLSNC ESLMTALASC KKLREIEFSG QCFEAMTFVN 1200
ILPNFVSLKI LSLKGQQFAD KETSEKFAQA LGSLRNLEEL LVPTGDGIHQ 1250
VAKLIVRQCL QLPCLRVLAF HDILDDESVI EIGAATSGSF QKLENLDISM 1300
NHKITEEGYR NFFQALDNLP NLQMLNICRN IPGRIQVQAT TVKALCHCVS 1350
RLPSLTRLGM LSWLLDEEDM KVINDVKERH PQSKRLTIFW KWIVPFSPVV 1400
LE 1402
Length:1,402
Mass (Da):159,664
Last modified:October 1, 2000 - v1
Checksum:iC1DFFBA359893E0D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF242433 Genomic DNA. Translation: AAF82749.1.
RefSeqiNP_067520.1. NM_021545.1.
UniGeneiMm.218759.

Genome annotation databases

GeneIDi53880.
KEGGimmu:53880.
UCSCiuc011zdt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF242433 Genomic DNA. Translation: AAF82749.1 .
RefSeqi NP_067520.1. NM_021545.1.
UniGenei Mm.218759.

3D structure databases

ProteinModelPortali Q9JIB3.
SMRi Q9JIB3. Positions 60-128, 140-244, 276-345, 1071-1160, 1181-1219, 1288-1388.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I32.001.

PTM databases

PhosphoSitei Q9JIB3.

Proteomic databases

PRIDEi Q9JIB3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 53880.
KEGGi mmu:53880.
UCSCi uc011zdt.1. mouse.

Organism-specific databases

CTDi 53880.
MGIi MGI:1858256. Naip7.

Phylogenomic databases

HOVERGENi HBG050689.
InParanoidi Q9JIB3.
KOi K12807.

Miscellaneous databases

NextBioi 310753.
PROi Q9JIB3.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9JIB3.

Family and domain databases

Gene3Di 1.10.1170.10. 3 hits.
InterProi IPR001370. BIR.
IPR007111. NACHT_NTPase.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00653. BIR. 3 hits.
[Graphical view ]
SMARTi SM00238. BIR. 3 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS01282. BIR_REPEAT_1. 2 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50837. NACHT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiBIR1G_MOUSE
AccessioniPrimary (citable) accession number: Q9JIB3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi