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Q9JIB3

- BIR1G_MOUSE

UniProt

Q9JIB3 - BIR1G_MOUSE

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Protein

Baculoviral IAP repeat-containing protein 1g

Gene

Naip7

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Prevents motor-neuron apoptosis induced by a variety of signals.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi315 – 3151ZincPROSITE-ProRule annotation
Metal bindingi318 – 3181ZincPROSITE-ProRule annotation
Metal bindingi335 – 3351ZincPROSITE-ProRule annotation
Metal bindingi342 – 3421ZincPROSITE-ProRule annotation
Binding sitei476 – 4761ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. apoptotic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Apoptosis

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Protein family/group databases

MEROPSiI32.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Baculoviral IAP repeat-containing protein 1g
Alternative name(s):
Neuronal apoptosis inhibitory protein 7
Gene namesi
Name:Naip7
Synonyms:Birc1g
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:1858256. Naip7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14021402Baculoviral IAP repeat-containing protein 1gPRO_0000122346Add
BLAST

Proteomic databases

PRIDEiQ9JIB3.

PTM databases

PhosphoSiteiQ9JIB3.

Expressioni

Gene expression databases

GenevestigatoriQ9JIB3.

Structurei

3D structure databases

ProteinModelPortaliQ9JIB3.
SMRiQ9JIB3. Positions 60-128, 140-244, 276-345, 1056-1137, 1180-1218, 1289-1331.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati60 – 12768BIR 1Add
BLAST
Repeati159 – 22769BIR 2Add
BLAST
Repeati278 – 34568BIR 3Add
BLAST
Domaini464 – 759296NACHTPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 3 BIR repeats.PROSITE-ProRule annotation
Contains 1 NACHT domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOVERGENiHBG050689.
InParanoidiQ9JIB3.
KOiK12807.

Family and domain databases

Gene3Di1.10.1170.10. 3 hits.
InterProiIPR001370. BIR.
IPR007111. NACHT_NTPase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00653. BIR. 3 hits.
[Graphical view]
SMARTiSM00238. BIR. 3 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS01282. BIR_REPEAT_1. 2 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50837. NACHT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JIB3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEHGESSED RISEIDYEFL AELSARFGMN LVQLAKSQEE EDHKERMKMK
60 70 80 90 100
KGFNSQMRSE AKRLKTFESY DTFRSWTPQE MAAAGFYHTG VKLGVQCFCC
110 120 130 140 150
SLILFGNSLR KLPIERHKKL RPECEFLQGK DVGNIGKYDI RVKSPEKMLR
160 170 180 190 200
GGKARYHEEE ARLESFEDWP FYAHGTSPRV LSAAGFVFTG KRDTVQCFSC
210 220 230 240 250
GGSLGNWEEG DDPWKEHAKW FPKCEFLQSK KSSEEIAQYI QGYEGFVHVT
260 270 280 290 300
GEHFVKSWVR RELPMVSAYC NDSVFANEEL RMDMFKDWPQ ESPVGVEALV
310 320 330 340 350
RAGFFYTGKK DIVRCFSCGG CLEKWAEGDD PMEDHIKFFP ECVFLQTLKS
360 370 380 390 400
SAEVIPTLQS QYALPEATET TRESNHGDAA AVHSTVVDLG RSEAQWFQEA
410 420 430 440 450
RSLSEQLRDT YTKTSFCHMN LPEVCSSLGT DHLLSCDVSI ISKHISQPVQ
460 470 480 490 500
GALTIPEVFS NLSSVMCVEG EAGSGKTTFL KRIAFLWASG CCPLLYRFQL
510 520 530 540 550
VFYLSLSSIT PDQGLDNIIC TQLLGAGGCI SEVCLSSSIQ QLQHQVLFLL
560 570 580 590 600
DDYSGLASLP QALHTLITKN YLFRTCLLIA VHTNRVRDIR PYLGTSLEIQ
610 620 630 640 650
EFPFYNTVFV LRKFFSHDII CVEKLIIYFS ENKDLQGVYK TPLFVAAVCN
660 670 680 690 700
DWNQNASAQD DFQDVTLFHS YMQYLSLKYK ATAESLQATV SSCGQLALTG
710 720 730 740 750
LFSSCFEFNS DDLAEAGVDE DVKLTTFLMS KFTAQRLRPV YRFLGPLFQE
760 770 780 790 800
FLAAVRLTEL LSSDRQEDQD LGLYYLRQID SPLKAINSFN IFLYYVSSHS
810 820 830 840 850
SSKAAPTVVS HLLQLVDEKE SLENMSENED YMKLHPQTFL WFQFVRGLWL
860 870 880 890 900
VSPESFSSFV SEHLLRLALI FAYESNTVAE CSPFILQFLR GRTLALRVLN
910 920 930 940 950
LEYFWDHPES LLLLRSLKVS INGNKMSSYV DYSFKTYFEN LQPPAINEEY
960 970 980 990 1000
TSAFEHVSEW RRNFAQDEEI IKNYENIWPR ALPDISEGYW NLSPKPCKIP
1010 1020 1030 1040 1050
KLEVQVNNMG PADQALLQVL MEVFSASQSI EFHLFNSSGF LESIRPALEL
1060 1070 1080 1090 1100
SKASVTKCSM SRLELSRAEQ ELLLTLPALQ SLEVSETNQL PDQLFHNLHK
1110 1120 1130 1140 1150
FLGLKELCVR LDGKPDVLSV LPEEFLNLHH MEKLSIRTST ESDLSKLVKF
1160 1170 1180 1190 1200
IQNFPNLHVF HLKCDFLSNC ESLMTALASC KKLREIEFSG QCFEAMTFVN
1210 1220 1230 1240 1250
ILPNFVSLKI LSLKGQQFAD KETSEKFAQA LGSLRNLEEL LVPTGDGIHQ
1260 1270 1280 1290 1300
VAKLIVRQCL QLPCLRVLAF HDILDDESVI EIGAATSGSF QKLENLDISM
1310 1320 1330 1340 1350
NHKITEEGYR NFFQALDNLP NLQMLNICRN IPGRIQVQAT TVKALCHCVS
1360 1370 1380 1390 1400
RLPSLTRLGM LSWLLDEEDM KVINDVKERH PQSKRLTIFW KWIVPFSPVV

LE
Length:1,402
Mass (Da):159,664
Last modified:October 1, 2000 - v1
Checksum:iC1DFFBA359893E0D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF242433 Genomic DNA. Translation: AAF82749.1.
RefSeqiNP_067520.1. NM_021545.1.
UniGeneiMm.218759.

Genome annotation databases

GeneIDi53880.
KEGGimmu:53880.
UCSCiuc011zdt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF242433 Genomic DNA. Translation: AAF82749.1 .
RefSeqi NP_067520.1. NM_021545.1.
UniGenei Mm.218759.

3D structure databases

ProteinModelPortali Q9JIB3.
SMRi Q9JIB3. Positions 60-128, 140-244, 276-345, 1056-1137, 1180-1218, 1289-1331.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I32.001.

PTM databases

PhosphoSitei Q9JIB3.

Proteomic databases

PRIDEi Q9JIB3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 53880.
KEGGi mmu:53880.
UCSCi uc011zdt.1. mouse.

Organism-specific databases

CTDi 53880.
MGIi MGI:1858256. Naip7.

Phylogenomic databases

HOVERGENi HBG050689.
InParanoidi Q9JIB3.
KOi K12807.

Miscellaneous databases

NextBioi 310753.
PROi Q9JIB3.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9JIB3.

Family and domain databases

Gene3Di 1.10.1170.10. 3 hits.
InterProi IPR001370. BIR.
IPR007111. NACHT_NTPase.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00653. BIR. 3 hits.
[Graphical view ]
SMARTi SM00238. BIR. 3 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS01282. BIR_REPEAT_1. 2 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50837. NACHT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiBIR1G_MOUSE
AccessioniPrimary (citable) accession number: Q9JIB3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: October 1, 2000
Last modified: October 29, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3