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Q9JI83

- PLAC1_MOUSE

UniProt

Q9JI83 - PLAC1_MOUSE

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Protein

Placenta-specific protein 1

Gene
Plac1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

May play a role in placental development.1 Publication

GO - Biological processi

  1. placenta development Source: UniProtKB
  2. spongiotrophoblast layer developmental growth Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Names & Taxonomyi

Protein namesi
Recommended name:
Placenta-specific protein 1
Alternative name(s):
EPCS26
Gene namesi
Name:Plac1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:1926287. Plac1.

Subcellular locationi

Secreted Inferred

GO - Cellular componenti

  1. extracellular region Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323 Reviewed predictionAdd
BLAST
Chaini24 – 173150Placenta-specific protein 1PRO_0000251145Add
BLAST

Proteomic databases

PRIDEiQ9JI83.

PTM databases

PhosphoSiteiQ9JI83.

Expressioni

Tissue specificityi

Expressed in placenta.1 Publication

Developmental stagei

Strongly expressed at 7 dpc and gradually declines with the progression of embryogenesis. Expression detected from 7.5 to 14.5 dpc in ectoplacental cone, trophoblast giant cells, and labyrinthine trophoblasts.1 Publication

Gene expression databases

BgeeiQ9JI83.
CleanExiMM_PLAC1.
GenevestigatoriQ9JI83.

Structurei

3D structure databases

ProteinModelPortaliQ9JI83.
SMRiQ9JI83. Positions 24-122.

Family & Domainsi

Sequence similaritiesi

Belongs to the PLAC1 family.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG44687.
GeneTreeiENSGT00530000064049.
HOGENOMiHOG000049283.
HOVERGENiHBG080610.
InParanoidiQ9JI83.
OMAiFHELHLG.
OrthoDBiEOG73JKWP.
PhylomeDBiQ9JI83.
TreeFamiTF338479.

Family and domain databases

InterProiIPR001507. ZP_dom.
[Graphical view]
PfamiPF00100. Zona_pellucida. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9JI83-1 [UniParc]FASTAAdd to Basket

« Hide

MNLRKFLGGT VLVAFMLFSY SEQNQVNVLC STDWFMVTVH PFLLNNDVYV    50
HFYEVHLGLG CPPNHVHPHF YQFHYRVTEC GIRIKAVSPD VVIYSSEIHY 100
ASKGSSTKYV IPVSCAAPRR SPWLTKPYSA KAPSNNMGAT PKNDTSYHVF 150
TLPEPSEQPN CSCPPYVYNQ KSM 173
Length:173
Mass (Da):19,626
Last modified:October 1, 2000 - v1
Checksum:i674AEF2B68181162
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti69 – 691H → R in AAH51666. 1 Publication
Sequence conflicti157 – 1571E → G in AAH51666. 1 Publication
Sequence conflicti159 – 1591P → R in BAE26717. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF250838 mRNA. Translation: AAF81275.1.
AF234653 mRNA. Translation: AAG22595.1.
AK005501 mRNA. Translation: BAB24083.1.
AK145876 mRNA. Translation: BAE26717.1.
BC051666 mRNA. Translation: AAH51666.1.
CCDSiCCDS30128.1.
RefSeqiNP_062411.1. NM_019538.4.
XP_006541587.1. XM_006541524.1.
XP_006541588.1. XM_006541525.1.
UniGeneiMm.274842.

Genome annotation databases

EnsembliENSMUST00000074861; ENSMUSP00000074404; ENSMUSG00000061082.
ENSMUST00000114843; ENSMUSP00000110492; ENSMUSG00000061082.
ENSMUST00000174390; ENSMUSP00000133862; ENSMUSG00000061082.
GeneIDi56096.
KEGGimmu:56096.
UCSCiuc009tet.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF250838 mRNA. Translation: AAF81275.1 .
AF234653 mRNA. Translation: AAG22595.1 .
AK005501 mRNA. Translation: BAB24083.1 .
AK145876 mRNA. Translation: BAE26717.1 .
BC051666 mRNA. Translation: AAH51666.1 .
CCDSi CCDS30128.1.
RefSeqi NP_062411.1. NM_019538.4.
XP_006541587.1. XM_006541524.1.
XP_006541588.1. XM_006541525.1.
UniGenei Mm.274842.

3D structure databases

ProteinModelPortali Q9JI83.
SMRi Q9JI83. Positions 24-122.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q9JI83.

Proteomic databases

PRIDEi Q9JI83.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000074861 ; ENSMUSP00000074404 ; ENSMUSG00000061082 .
ENSMUST00000114843 ; ENSMUSP00000110492 ; ENSMUSG00000061082 .
ENSMUST00000174390 ; ENSMUSP00000133862 ; ENSMUSG00000061082 .
GeneIDi 56096.
KEGGi mmu:56096.
UCSCi uc009tet.1. mouse.

Organism-specific databases

CTDi 10761.
MGIi MGI:1926287. Plac1.

Phylogenomic databases

eggNOGi NOG44687.
GeneTreei ENSGT00530000064049.
HOGENOMi HOG000049283.
HOVERGENi HBG080610.
InParanoidi Q9JI83.
OMAi FHELHLG.
OrthoDBi EOG73JKWP.
PhylomeDBi Q9JI83.
TreeFami TF338479.

Miscellaneous databases

NextBioi 311924.
PROi Q9JI83.
SOURCEi Search...

Gene expression databases

Bgeei Q9JI83.
CleanExi MM_PLAC1.
Genevestigatori Q9JI83.

Family and domain databases

InterProi IPR001507. ZP_dom.
[Graphical view ]
Pfami PF00100. Zona_pellucida. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "cDNA subtraction cloning reveals novel genes whose temporal and spatial expression indicates association with trophoblast invasion."
    Hemberger M., Himmelbauer H., Ruschmann J., Zeitz C., Fundele R.
    Dev. Biol. 222:158-169(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Placenta.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo.

Entry informationi

Entry nameiPLAC1_MOUSE
AccessioniPrimary (citable) accession number: Q9JI83
Secondary accession number(s): Q3UKT4, Q80WW3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 1, 2000
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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