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Q9JI54 (Q9JI54_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Hmga2 RGD 620617
Synonyms:Hmgi-c EMBL AAF91385.1
OrganismRattus norvegicus (Rat) EMBL AAF91385.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length37 AA.
Sequence statusFragment.
Protein existencePredicted

Ontologies

Gene Ontology (GO)
   Biological_processDNA damage response, detection of DNA damage

Inferred from electronic annotation. Source: Ensembl

adrenal gland development

Inferred from electronic annotation. Source: Ensembl

base-excision repair

Inferred from electronic annotation. Source: Ensembl

cell proliferation in forebrain

Inferred from electronic annotation. Source: Ensembl

chondrocyte differentiation

Inferred from electronic annotation. Source: Ensembl

chondrocyte proliferation

Inferred from electronic annotation. Source: Ensembl

chromosome breakage

Inferred from electronic annotation. Source: Ensembl

endodermal cell differentiation

Inferred from electronic annotation. Source: Ensembl

epithelial to mesenchymal transition

Inferred from electronic annotation. Source: Ensembl

fat cell differentiation

Inferred from electronic annotation. Source: Ensembl

fat pad development

Inferred from electronic annotation. Source: Ensembl

histone H2A-S139 phosphorylation

Inferred from electronic annotation. Source: Ensembl

male gonad development

Inferred from electronic annotation. Source: Ensembl

mesodermal cell differentiation

Inferred from electronic annotation. Source: Ensembl

mesodermal-endodermal cell signaling

Inferred from electronic annotation. Source: Ensembl

mitotic G2 DNA damage checkpoint

Inferred from electronic annotation. Source: Ensembl

negative regulation by host of viral transcription

Inferred from electronic annotation. Source: Ensembl

negative regulation of DNA binding

Inferred from electronic annotation. Source: Ensembl

negative regulation of JAK-STAT cascade

Inferred from direct assay PubMed 11390395. Source: RGD

negative regulation of apoptotic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of astrocyte differentiation

Inferred from electronic annotation. Source: Ensembl

negative regulation of double-strand break repair via nonhomologous end joining

Inferred from electronic annotation. Source: Ensembl

negative regulation of intracellular steroid hormone receptor signaling pathway

Inferred from direct assay PubMed 11390395. Source: RGD

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

Inferred from electronic annotation. Source: Ensembl

negative regulation of transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 11390395. Source: RGD

oncogene-induced cell senescence

Inferred from electronic annotation. Source: Ensembl

pituitary gland development

Inferred from electronic annotation. Source: Ensembl

positive regulation of apoptotic process

Inferred from electronic annotation. Source: Ensembl

positive regulation of cell cycle arrest

Inferred from electronic annotation. Source: Ensembl

positive regulation of cellular response to X-ray

Inferred from electronic annotation. Source: Ensembl

positive regulation of cellular senescence

Inferred from electronic annotation. Source: Ensembl

positive regulation of multicellular organism growth

Inferred from electronic annotation. Source: Ensembl

positive regulation of response to DNA damage stimulus

Inferred from electronic annotation. Source: Ensembl

positive regulation of sequence-specific DNA binding transcription factor activity

Inferred from mutant phenotype PubMed 9311991. Source: RGD

positive regulation of stem cell proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription regulatory region DNA binding

Inferred from electronic annotation. Source: Ensembl

regulation of cellular response to drug

Inferred from electronic annotation. Source: Ensembl

regulation of growth hormone secretion

Inferred from electronic annotation. Source: Ensembl

regulation of stem cell maintenance

Inferred from electronic annotation. Source: Ensembl

response to virus

Inferred from electronic annotation. Source: Ensembl

senescence-associated heterochromatin focus assembly

Inferred from electronic annotation. Source: Ensembl

signal transduction

Inferred from mutant phenotype PubMed 11390395. Source: RGD

somatic stem cell maintenance

Inferred from electronic annotation. Source: Ensembl

spermatogenesis

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentSMAD protein complex

Inferred from electronic annotation. Source: Ensembl

nuclear chromosome

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from direct assay PubMed 11390395. Source: RGD

protein-DNA complex

Inferred from electronic annotation. Source: Ensembl

senescence-associated heterochromatin focus

Inferred from electronic annotation. Source: Ensembl

   Molecular_function5'-deoxyribose-5-phosphate lyase activity

Inferred from electronic annotation. Source: Ensembl

AT DNA binding

Inferred from electronic annotation. Source: Ensembl

DNA binding, bending

Inferred from electronic annotation. Source: Ensembl

DNA-(apurinic or apyrimidinic site) lyase activity

Inferred from electronic annotation. Source: Ensembl

DNA-dependent protein kinase activity

Inferred from electronic annotation. Source: Ensembl

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

Inferred from electronic annotation. Source: Ensembl

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

Inferred from electronic annotation. Source: Ensembl

cAMP response element binding

Inferred from electronic annotation. Source: Ensembl

core promoter binding

Inferred from electronic annotation. Source: Ensembl

enzyme binding

Inferred from physical interaction PubMed 11390395. Source: RGD

protein binding transcription factor activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue371 EMBL AAF91385.1

Sequences

Sequence LengthMass (Da)Tools
Q9JI54 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 7E23A16F3EB01AC2

FASTA373,828
        10         20         30 
MSARGEGAGQ PSTSAQGQPA TPAPQKRGRG RPRKQPQ 

« Hide

References

[1]"AP-2alpha-dependent rat non-histone chromosomal protein HMGI-C expression in salivary epithelial cells."
Wen X., Lin H.H., Deng H.-T., Hajyan K., Ann D.K.
Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Sprague-Dawley EMBL AAF91385.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF261719 Genomic DNA. Translation: AAF91385.1.
UniGeneRn.29981.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

RGD620617. Hmga2.

Phylogenomic databases

PhylomeDBQ9JI54.

Gene expression databases

GenevestigatorQ9JI54.

Family and domain databases

InterProIPR017956. AT_hook_DNA-bd_motif.
IPR000637. HMGI/Y_DNA-bd_CS.
[Graphical view]
PfamPF02178. AT_hook. 1 hit.
[Graphical view]
PROSITEPS00354. HMGI_Y. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9JI54_RAT
AccessionPrimary (citable) accession number: Q9JI54
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)