Q9JI54 (Q9JI54_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
High mobility group protein HMGI-C EMBL AAF91385.1

Gene names

Name:	Hmga2 RGD 620617
Synonyms:	Hmgi-c EMBL AAF91385.1

Organism

Rattus norvegicus (Rat) EMBL AAF91385.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	37 AA.
Sequence status	Fragment.
Protein existence	Predicted

Ontologies

Gene Ontology (GO)
Biological_process	DNA damage response, detection of DNA damage Inferred from electronic annotation. Source: Compara adrenal gland development Inferred from electronic annotation. Source: Compara base-excision repair Inferred from electronic annotation. Source: Compara cell proliferation in forebrain Inferred from electronic annotation. Source: Compara chondrocyte differentiation Inferred from electronic annotation. Source: Compara chondrocyte proliferation Inferred from electronic annotation. Source: Compara chromosome breakage Inferred from electronic annotation. Source: Compara endodermal cell differentiation Inferred from electronic annotation. Source: Compara epithelial to mesenchymal transition Inferred from electronic annotation. Source: Compara fat cell differentiation Inferred from electronic annotation. Source: Compara fat pad development Inferred from electronic annotation. Source: Compara histone H2A-S139 phosphorylation Inferred from electronic annotation. Source: Compara male gonad development Inferred from electronic annotation. Source: Compara mesodermal cell differentiation Inferred from electronic annotation. Source: Compara mesodermal-endodermal cell signaling Inferred from electronic annotation. Source: Compara mitotic G2 DNA damage checkpoint Inferred from electronic annotation. Source: Compara negative regulation by host of viral transcription Inferred from electronic annotation. Source: Compara negative regulation of DNA binding Inferred from electronic annotation. Source: Compara negative regulation of JAK-STAT cascade Inferred from direct assay PubMed 11390395. Source: RGD negative regulation of apoptotic process Inferred from electronic annotation. Source: Compara negative regulation of astrocyte differentiation Inferred from electronic annotation. Source: Compara negative regulation of double-strand break repair via nonhomologous end joining Inferred from electronic annotation. Source: Compara negative regulation of intracellular steroid hormone receptor signaling pathway Inferred from direct assay PubMed 11390395. Source: RGD negative regulation of retroviral genome replication Inferred from electronic annotation. Source: Compara negative regulation of transcription from RNA polymerase II promoter Inferred from direct assay PubMed 11390395. Source: RGD oncogene-induced senescence Inferred from electronic annotation. Source: Compara pituitary gland development Inferred from electronic annotation. Source: Compara positive regulation of apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of cell cycle arrest Inferred from electronic annotation. Source: Compara positive regulation of cellular response to X-ray Inferred from electronic annotation. Source: Compara positive regulation of cellular senescence Inferred from electronic annotation. Source: Compara positive regulation of multicellular organism growth Inferred from electronic annotation. Source: Compara positive regulation of response to DNA damage stimulus Inferred from electronic annotation. Source: Compara positive regulation of sequence-specific DNA binding transcription factor activity Inferred from mutant phenotype PubMed 9311991. Source: RGD positive regulation of stem cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of transcription regulatory region DNA binding Inferred from electronic annotation. Source: Compara regulation of cellular response to drug Inferred from electronic annotation. Source: Compara regulation of growth hormone secretion Inferred from electronic annotation. Source: Compara regulation of stem cell maintenance Inferred from electronic annotation. Source: Compara response to virus Inferred from electronic annotation. Source: Compara senescence-associated heterochromatin focus assembly Inferred from electronic annotation. Source: Compara signal transduction Inferred from mutant phenotype PubMed 11390395. Source: RGD somatic stem cell maintenance Inferred from electronic annotation. Source: Compara spermatogenesis Inferred from electronic annotation. Source: Compara
Cellular_component	SMAD protein complex Inferred from electronic annotation. Source: Compara nuclear chromosome Inferred from electronic annotation. Source: Compara nucleus Inferred from direct assay PubMed 11390395. Source: RGD protein-DNA complex Inferred from electronic annotation. Source: Compara senescence-associated heterochromatin focus Inferred from electronic annotation. Source: Compara
Molecular_function	5'-deoxyribose-5-phosphate lyase activity Inferred from electronic annotation. Source: Compara AT DNA binding Inferred from electronic annotation. Source: Compara DNA binding, bending Inferred from electronic annotation. Source: Compara DNA-(apurinic or apyrimidinic site) lyase activity Inferred from electronic annotation. Source: Compara DNA-dependent protein kinase activity Inferred from electronic annotation. Source: Compara RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Inferred from electronic annotation. Source: Compara RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Inferred from electronic annotation. Source: Compara cAMP response element binding Inferred from electronic annotation. Source: Compara core promoter binding Inferred from electronic annotation. Source: Compara nucleosomal DNA binding Inferred from electronic annotation. Source: Compara protein binding transcription factor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	37	1	EMBL AAF91385.1

Sequences

	Sequence		Length	Mass (Da)
	Q9JI54 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 7E23A16F3EB01AC2	FASTA	37	3,828
	10 20 30 MSARGEGAGQ PSTSAQGQPA TPAPQKRGRG RPRKQPQ

References

[1]	"AP-2alpha-dependent rat non-histone chromosomal protein HMGI-C expression in salivary epithelial cells." Wen X., Lin H.H., Deng H.-T., Hajyan K., Ann D.K. Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Sprague-Dawley EMBL AAF91385.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF261719 Genomic DNA. Translation: AAF91385.1.
IPI	IPI00212599.
UniGene	Rn.29981.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
RGD	620617. Hmga2.
Gene expression databases
Genevestigator	Q9JI54.
Family and domain databases
InterPro	IPR017956. AT_hook_DNA-bd_motif. IPR000637. HMGI/Y_DNA-bd_CS. [Graphical view]
Pfam	PF02178. AT_hook. 1 hit. [Graphical view]
PROSITE	PS00354. HMGI_Y. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9JI54_RAT

Accession

Primary (citable) accession number: Q9JI54

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)