Reviewed, UniProtKB/Swiss-Prot Q9JHX6 (ALLC_MOUSE)

Names and origin

Protein names

Recommended name:
    Probable allantoicase
    EC=3.5.3.4
Alternative name(s):
    Allantoate amidinohydrolase

Gene names

Name:

Allc

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	414 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.
Catalytic activity	Allantoate + H2O = (S)-ureidoglycolate + urea.
Sequence similarities	Belongs to the allantoicase family.

Ontologies

Keywords
Molecular function	Hydrolase
Gene Ontology (GO)
Molecular function	allantoicase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 414	414	Probable allantoicase		PRO_0000205907

Sequences

	Sequence		Length	Mass (Da)
	Q9JHX6-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: B2145D6DC7386617	FASTA	414	46,206
	10 20 30 40 50 60 MADTPKEGKL TRFLDFTQLI DLASECVGGK VLFATDDFFG PAENLIKSDS PTFKEHEYTE 70 80 90 100 110 120 FGKWVDGWET RRKRIPGHDW CVIQLGIQGI IRGIDVDISY FSGNHAPRMS IQAANLSEED 130 140 150 160 170 180 TMSNIPPRGV RMGTAATPEE FEAVTELKSH SWDYLVPMSE LKLGDPDSSH NYYFVNSQQR 190 200 210 220 230 240 WTHIRLNIFP DGGVARLRVY GTGQRDWAAL GSTEPVDLVA IAFGGVCVGF SNAHFGHPNN 250 260 270 280 290 300 MIGVGEPKSI ADGWETARRL DRPPVLEASE NGLLLVPGCE WAVFRLAHPG VITQIEIDTK 310 320 330 340 350 360 YFKGNCPNSC KVDGCILTTL EEEDMIRHNW NLPAHKWKSL LPVTKLIPNQ NHLLDSLTLE 370 380 390 400 410 LQDVITHAMI TIAPDGGVSR LRLKGFPSSI CLLRPLREKP LLRFSLKTGF RANL

References

[1]	"Molecular cloning of mouse allantoicase cDNA." Vigetti D., Monetti C., Bernardini G. Biochim. Biophys. Acta 1519:117-121(2001) [PubMed: 11406280] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: CD-1.
[2]	"Genomic organization and chromosome localization of the murine and human allantoicase gene." Vigetti D., Monetti C., Prati M., Gornati R., Bernardini G. Gene 289:13-17(2002) [PubMed: 12036579] [Abstract] Cited for: GENE STRUCTURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF278712 mRNA. Translation: AAF86348.1.
IPI	IPI00119983.
UniGene	Mm.84927
3D structure databases
HSSP	HSSP built from PDB template 1O59 based on UniProtKB P25335.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9JHX6.
2-D gel databases
REPRODUCTION-2DPAGE	Q9JHX6.
Proteomic databases
PRIDE	Q9JHX6.
Genome annotation databases
Ensembl	ENSMUST00000020965; ENSMUSP00000020965; ENSMUSG00000020636; Mus musculus. [Genome view] ENSMUST00000110917; ENSMUSP00000106542; ENSMUSG00000020636; Mus musculus. [Genome view]
UCSC	uc007nfp.1. mouse.
Organism-specific databases
MGI	MGI:2136971. Allc.
Phylogenomic databases
HOGENOM	Q9JHX6.
HOVERGEN	Q9JHX6.
Enzyme and pathway databases
BRENDA	3.5.3.4. 244.
Gene expression databases
ArrayExpress	Q9JHX6.
Bgee	Q9JHX6.
CleanEx	MM_ALLC.
Genevestigator	Q9JHX6.
GermOnline	ENSMUSG00000020636. Mus musculus.
Family and domain databases
InterPro	IPR005164. Allantoicase. IPR015908. Allantoicase_region. [Graphical view]
PANTHER	PTHR12045. Allantoicase. 1 hit.
Pfam	PF03561. Allantoicase. 2 hits. [Graphical view]
TIGRFAMs	TIGR02961. allantoicase. 1 hit.
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

ALLC_MOUSE

Accession

Primary (citable) accession number: Q9JHX6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	October 1, 2000
Last modified:	October 13, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)