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Protein

Arfaptin-1

Gene

Arfip1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Putative target protein of ADP-ribosylation factor.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Arfaptin-1
Alternative name(s):
ADP-ribosylation factor-interacting protein 1
Gene namesi
Name:Arfip1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi708401. Arfip1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000646662 – 366Arfaptin-1Add BLAST365

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei5PhosphoserineBy similarity1
Modified residuei36PhosphoserineBy similarity1
Modified residuei39PhosphoserineCombined sources1
Modified residuei69PhosphoserineBy similarity1
Modified residuei79PhosphoserineBy similarity1
Modified residuei125PhosphoserineBy similarity1
Modified residuei354PhosphothreonineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ9JHU5.
PeptideAtlasiQ9JHU5.
PRIDEiQ9JHU5.

PTM databases

iPTMnetiQ9JHU5.
PhosphoSitePlusiQ9JHU5.

Expressioni

Gene expression databases

BgeeiENSRNOG00000010533.
ExpressionAtlasiQ9JHU5. baseline and differential.
GenevisibleiQ9JHU5. RN.

Interactioni

Subunit structurei

Interacts with non-myristoylated GTP-bound ARF3, but not to GDP-bound ARF3, and also to ARF1. Binds with lower affinity to ARF5 and with very little affinity to ARF6 (By similarity).By similarity

Protein-protein interaction databases

IntActiQ9JHU5. 1 interactor.
MINTiMINT-1775982.
STRINGi10116.ENSRNOP00000014236.

Structurei

3D structure databases

ProteinModelPortaliQ9JHU5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini146 – 346AHPROSITE-ProRule annotationAdd BLAST201

Sequence similaritiesi

Contains 1 AH domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3876. Eukaryota.
ENOG410YJUM. LUCA.
GeneTreeiENSGT00500000044828.
HOGENOMiHOG000236308.
HOVERGENiHBG050564.
InParanoidiQ9JHU5.
KOiK20314.
PhylomeDBiQ9JHU5.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR010504. AH_dom.
IPR030793. Arfaptin-1.
IPR030798. Arfaptin_fam.
[Graphical view]
PANTHERiPTHR12141. PTHR12141. 1 hit.
PTHR12141:SF4. PTHR12141:SF4. 1 hit.
PfamiPF06456. Arfaptin. 1 hit.
[Graphical view]
SMARTiSM01015. Arfaptin. 1 hit.
[Graphical view]
PROSITEiPS50870. AH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9JHU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEESPKNSA AEIPVTSNGE VGDAHEHGYN RDLKHSLPSG LGLSETQITS
60 70 80 90 100
HGFDSTKEGV TEAGASQGSS APPLPCVLSP SRVAASQLTQ HAGGQRTHTK
110 120 130 140 150
GGPVILADEI KNPAMEKLEL VRKWSLNTYK CTRQIISEKL GRGSRTVDLE
160 170 180 190 200
LEAQIDILRD NKKKYENILK LAQTLSTQLF QMVHTQKQLG DAFADLSLKS
210 220 230 240 250
LELHEEFGYN ADTQKLLAKN GETLLGAINF FIASVNTLVN KTIEDTLMTV
260 270 280 290 300
KQYENARIEY DAYRTDLEEL NLGPRDANTL PKIEQSQHLF QIHKEKYDKM
310 320 330 340 350
RSDVSVKLKF LEENKVKVLR NQLALFHSAV AAYFAGNQKQ LEQTLKQFHV
360
KLKTPGVDAP SWLEEQ
Length:366
Mass (Da):40,779
Last modified:October 1, 2000 - v1
Checksum:i1737B54006E30FAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY004875 mRNA. Translation: AAF91077.1.
RefSeqiNP_068531.1. NM_021763.1.
UniGeneiRn.162603.
Rn.232726.

Genome annotation databases

EnsembliENSRNOT00000014236; ENSRNOP00000014236; ENSRNOG00000010533.
GeneIDi60382.
KEGGirno:60382.
UCSCiRGD:708401. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY004875 mRNA. Translation: AAF91077.1.
RefSeqiNP_068531.1. NM_021763.1.
UniGeneiRn.162603.
Rn.232726.

3D structure databases

ProteinModelPortaliQ9JHU5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9JHU5. 1 interactor.
MINTiMINT-1775982.
STRINGi10116.ENSRNOP00000014236.

PTM databases

iPTMnetiQ9JHU5.
PhosphoSitePlusiQ9JHU5.

Proteomic databases

PaxDbiQ9JHU5.
PeptideAtlasiQ9JHU5.
PRIDEiQ9JHU5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000014236; ENSRNOP00000014236; ENSRNOG00000010533.
GeneIDi60382.
KEGGirno:60382.
UCSCiRGD:708401. rat.

Organism-specific databases

CTDi27236.
RGDi708401. Arfip1.

Phylogenomic databases

eggNOGiKOG3876. Eukaryota.
ENOG410YJUM. LUCA.
GeneTreeiENSGT00500000044828.
HOGENOMiHOG000236308.
HOVERGENiHBG050564.
InParanoidiQ9JHU5.
KOiK20314.
PhylomeDBiQ9JHU5.

Miscellaneous databases

PROiQ9JHU5.

Gene expression databases

BgeeiENSRNOG00000010533.
ExpressionAtlasiQ9JHU5. baseline and differential.
GenevisibleiQ9JHU5. RN.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR010504. AH_dom.
IPR030793. Arfaptin-1.
IPR030798. Arfaptin_fam.
[Graphical view]
PANTHERiPTHR12141. PTHR12141. 1 hit.
PTHR12141:SF4. PTHR12141:SF4. 1 hit.
PfamiPF06456. Arfaptin. 1 hit.
[Graphical view]
SMARTiSM01015. Arfaptin. 1 hit.
[Graphical view]
PROSITEiPS50870. AH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARFP1_RAT
AccessioniPrimary (citable) accession number: Q9JHU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.