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Protein

Arfaptin-1

Gene

Arfip1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Putative target protein of ADP-ribosylation factor.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Arfaptin-1
Alternative name(s):
ADP-ribosylation factor-interacting protein 1
Gene namesi
Name:Arfip1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi708401 Arfip1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000646662 – 366Arfaptin-1Add BLAST365

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei5PhosphoserineBy similarity1
Modified residuei36PhosphoserineBy similarity1
Modified residuei39PhosphoserineCombined sources1
Modified residuei69PhosphoserineBy similarity1
Modified residuei79PhosphoserineBy similarity1
Modified residuei125PhosphoserineBy similarity1
Modified residuei354PhosphothreonineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ9JHU5
PeptideAtlasiQ9JHU5
PRIDEiQ9JHU5

PTM databases

iPTMnetiQ9JHU5
PhosphoSitePlusiQ9JHU5

Expressioni

Gene expression databases

BgeeiENSRNOG00000010533
ExpressionAtlasiQ9JHU5 baseline and differential
GenevisibleiQ9JHU5 RN

Interactioni

Subunit structurei

Interacts with non-myristoylated GTP-bound ARF3, but not to GDP-bound ARF3, and also to ARF1. Binds with lower affinity to ARF5 and with very little affinity to ARF6 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ9JHU5, 1 interactor
STRINGi10116.ENSRNOP00000014236

Structurei

3D structure databases

ProteinModelPortaliQ9JHU5
SMRiQ9JHU5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini146 – 346AHPROSITE-ProRule annotationAdd BLAST201

Phylogenomic databases

eggNOGiKOG3876 Eukaryota
ENOG410YJUM LUCA
GeneTreeiENSGT00500000044828
HOGENOMiHOG000236308
HOVERGENiHBG050564
InParanoidiQ9JHU5
KOiK20314
PhylomeDBiQ9JHU5

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR010504 AH_dom
IPR030793 Arfaptin-1
IPR030798 Arfaptin_fam
PANTHERiPTHR12141 PTHR12141, 1 hit
PTHR12141:SF4 PTHR12141:SF4, 1 hit
PfamiView protein in Pfam
PF06456 Arfaptin, 1 hit
SMARTiView protein in SMART
SM01015 Arfaptin, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
PROSITEiView protein in PROSITE
PS50870 AH, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9JHU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEESPKNSA AEIPVTSNGE VGDAHEHGYN RDLKHSLPSG LGLSETQITS
60 70 80 90 100
HGFDSTKEGV TEAGASQGSS APPLPCVLSP SRVAASQLTQ HAGGQRTHTK
110 120 130 140 150
GGPVILADEI KNPAMEKLEL VRKWSLNTYK CTRQIISEKL GRGSRTVDLE
160 170 180 190 200
LEAQIDILRD NKKKYENILK LAQTLSTQLF QMVHTQKQLG DAFADLSLKS
210 220 230 240 250
LELHEEFGYN ADTQKLLAKN GETLLGAINF FIASVNTLVN KTIEDTLMTV
260 270 280 290 300
KQYENARIEY DAYRTDLEEL NLGPRDANTL PKIEQSQHLF QIHKEKYDKM
310 320 330 340 350
RSDVSVKLKF LEENKVKVLR NQLALFHSAV AAYFAGNQKQ LEQTLKQFHV
360
KLKTPGVDAP SWLEEQ
Length:366
Mass (Da):40,779
Last modified:October 1, 2000 - v1
Checksum:i1737B54006E30FAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY004875 mRNA Translation: AAF91077.1
RefSeqiNP_068531.1, NM_021763.1
UniGeneiRn.162603
Rn.232726

Genome annotation databases

EnsembliENSRNOT00000014236; ENSRNOP00000014236; ENSRNOG00000010533
GeneIDi60382
KEGGirno:60382
UCSCiRGD:708401 rat

Similar proteinsi

Entry informationi

Entry nameiARFP1_RAT
AccessioniPrimary (citable) accession number: Q9JHU5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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