Q9JHU2 (PALMD_MOUSE) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 72.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Palmdelphin | ||
| Gene names |
| ||
| Organism | Mus musculus (Mouse) [Reference proteome] | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus |
Protein attributes
| Sequence length | 551 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Subunit structure | Interacts with GLUL. Ref.6 |
| Subcellular location | Cytoplasm. Cell projection › dendrite. Cell projection › dendritic spine By similarity Ref.2 Ref.6. |
| Tissue specificity | Ubiquitous. Expressed at highest levels in the heart and lung. Ref.2 |
| Post-translational modification | Phosphorylated. Ref.6 |
| Sequence similarities | Belongs to the paralemmin family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cell projection Cytoplasm |
| Domain | Coiled coil |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | regulation of cell shape Inferred from electronic annotation. Source: InterPro |
| Cellular_component | cytoplasm Inferred from direct assay Ref.6. Source: UniProtKB dendritic spineInferred from electronic annotation. Source: UniProtKB-SubCell membraneInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 551 | 551 | Palmdelphin | PRO_0000262529 | |||||
Regions | |||||||||
| Coiled coil | 12 – 106 | 95 | Potential | ||||||
Amino acid modifications | |||||||||
| Modified residue | 135 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 321 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 370 | 1 | Phosphoserine Ref.7 | ||||||
| Modified residue | 375 | 1 | Phosphoserine Ref.7 | ||||||
| Modified residue | 385 | 1 | Phosphoserine Ref.7 | ||||||
| Modified residue | 515 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 520 | 1 | Phosphoserine By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 65 | 1 | R → K in CAC59696. Ref.2 | ||||||
| Sequence conflict | 65 | 1 | R → K in BAB29414. Ref.4 | ||||||
| Sequence conflict | 65 | 1 | R → K in BAE42708. Ref.4 | ||||||
| Sequence conflict | 144 | 1 | P → H in BAB29414. Ref.4 | ||||||
| Sequence conflict | 395 | 1 | V → I in BAE42708. Ref.4 | ||||||
| Sequence conflict | 470 | 1 | N → S in CAC59696. Ref.2 | ||||||
| Sequence conflict | 470 | 1 | N → S in BAB29414. Ref.4 | ||||||
| Sequence conflict | 470 | 1 | N → S in BAE42708. Ref.4 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "PALML, a novel paralemmin-related gene mapping on human chromosome 1p21." Andreu N., Escarceller M., Feather S., Devriendt K., Wolf A.S., Estivill X., Sumoy L. Gene 278:33-40(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: C57BL/6J. Tissue: Mammary gland. |
| [2] | "The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative." Hu B., Copeland N.G., Gilbert D.J., Jenkins N.A., Kilimann M.W. Biochem. Biophys. Res. Commun. 285:1369-1376(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Muscle. |
| [3] | The European IMAGE consortium Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
| [4] | "The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.  Hayashizaki Y.Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J and NOD. Tissue: Skin and Spleen. |
| [5] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: FVB/N. Tissue: Mammary tumor. |
| [6] | "Molecular characterization and immunohistochemical localization of palmdelphin, a cytosolic isoform of the paralemmin protein family implicated in membrane dynamics." Hu B., Petrasch-Parwez E., Laue M.M., Kilimann M.W. Eur. J. Cell Biol. 84:853-866(2005) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, INTERACTION WITH GLUL, SUBCELLULAR LOCATION, PHOSPHORYLATION. |
| [7] | "Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-370; SER-375 AND SER-385, MASS SPECTROMETRY. Tissue: Liver. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF263246 mRNA. Translation: AAK48507.1. AJ312215 mRNA. Translation: CAC59696.1. AL391037 mRNA. Translation: CAC01530.1. AK014531 mRNA. Translation: BAB29414.1. AK171869 mRNA. Translation: BAE42708.1. BC010193 mRNA. Translation: AAH10193.1. |
| IPI | IPI00314152. |
| RefSeq | NP_075734.3. NM_023245.3. |
| UniGene | Mm.253736. |
3D structure databases | |
| ProteinModelPortal | Q9JHU2. |
| ModBase | Search... |
PTM databases | |
| PhosphoSite | Q9JHU2. |
Proteomic databases | |
| PaxDb | Q9JHU2. |
| PRIDE | Q9JHU2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSMUST00000040097; ENSMUSP00000044693; ENSMUSG00000033377. |
| GeneID | 114301. |
| KEGG | mmu:114301. |
Organism-specific databases | |
| CTD | 54873. |
| MGI | MGI:2148896. Palmd. |
Phylogenomic databases | |
| eggNOG | NOG76459. |
| GeneTree | ENSGT00530000063206. |
| HOGENOM | HOG000115435. |
| HOVERGEN | HBG082103. |
| InParanoid | Q9JHU2. |
| KO | K16519. |
| OrthoDB | EOG49W2F8. |
Gene expression databases | |
| ArrayExpress | Q9JHU2. |
| Bgee | Q9JHU2. |
| CleanEx | MM_PALMD. |
| Genevestigator | Q9JHU2. |
| GermOnline | ENSMUSG00000033377. Mus musculus. |
Family and domain databases | |
| InterPro | IPR004965. Paralemmin. [Graphical view] |
| Pfam | PF03285. Paralemmin. 2 hits. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 368337. |
| SOURCE | Search... |
Entry information
| Entry name | PALMD_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q9JHU2 Secondary accession number(s): Q3TAG0, Q91X00, Q9D693 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| MGD cross-references Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |