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Protein

Annexin A9

Gene

Anxa9

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May act as a low affinity receptor for acetylcholine.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Annexin A9
Alternative name(s):
Annexin XXXI
Annexin-31
Annexin-9
Gene namesi
Name:Anxa9
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1923711. Anxa9.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000675061 – 345Annexin A9Add BLAST345

Proteomic databases

MaxQBiQ9JHQ0.
PaxDbiQ9JHQ0.
PRIDEiQ9JHQ0.

PTM databases

PhosphoSitePlusiQ9JHQ0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000015702.
CleanExiMM_ANXA9.
ExpressionAtlasiQ9JHQ0. baseline and differential.
GenevisibleiQ9JHQ0. MM.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000015846.

Structurei

3D structure databases

ProteinModelPortaliQ9JHQ0.
SMRiQ9JHQ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati43 – 110Annexin 1Add BLAST68
Repeati115 – 182Annexin 2Add BLAST68
Repeati199 – 264Annexin 3Add BLAST66
Repeati272 – 339Annexin 4Add BLAST68

Sequence similaritiesi

Belongs to the annexin family.Curated
Contains 4 annexin repeats.Curated

Keywords - Domaini

Annexin, Repeat

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
GeneTreeiENSGT00760000118972.
HOGENOMiHOG000158803.
HOVERGENiHBG061815.
InParanoidiQ9JHQ0.
KOiK17090.
OMAiTQRNPEH.
OrthoDBiEOG091G0B7B.
PhylomeDBiQ9JHQ0.
TreeFamiTF105452.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiIPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR009116. AnnexinXXXI.
[Graphical view]
PfamiPF00191. Annexin. 4 hits.
[Graphical view]
PRINTSiPR00196. ANNEXIN.
PR01812. ANNEXINXXXI.
SMARTiSM00335. ANX. 4 hits.
[Graphical view]
PROSITEiPS00223. ANNEXIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JHQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASCGPLGT SLTQEILSSL GLADKTAAWG TLGTLRTFLS FSVDKDVQRL
60 70 80 90 100
LKAIAGQGVD YDTIVDVLTN RSREQRQLIS RAFQERTKQD LLKSLQAALS
110 120 130 140 150
GNLEKIVVAL LQPAAQFDAQ ELRTALKTSG SAEDVALEIL ATRAAPGLQA
160 170 180 190 200
CLAVYKHDFQ VEAEEDIRTE TNGILQDLLL ALSKGDRESY SGIIDYNLEE
210 220 230 240 250
QDVRALQQAG ESSTAGQWVL LLTQRSPEHL IRVFDQYRRC TGQELEDAIR
260 270 280 290 300
NCFHGDAQLA LISLASMLRN TALYFANKLH QALQETEPNF QVLTRVLISR
310 320 330 340
SESDLLSIRA EFKKKFGKSL YSSLQDVVRG DCRSALLALC RAEDI
Length:345
Mass (Da):38,110
Last modified:July 5, 2005 - v2
Checksum:i638EF32FFFFB6AF0
GO

Sequence cautioni

The sequence CAB95698 differs from that shown. Reason: Frameshift at position 8.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti145 – 147APG → FSR in CAB95698 (Ref. 2) Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF437742 Genomic DNA. Translation: AAO37381.1.
AJ401160 mRNA. Translation: CAB95698.1. Frameshift.
AK010128 mRNA. Translation: BAB26719.1.
AK003395 mRNA. Translation: BAB22761.1.
BC062140 mRNA. Translation: AAH62140.1.
CCDSiCCDS50989.1.
RefSeqiNP_001078852.1. NM_001085383.1.
NP_076117.2. NM_023628.2.
XP_011238537.1. XM_011240235.1.
UniGeneiMm.218844.

Genome annotation databases

EnsembliENSMUST00000015846; ENSMUSP00000015846; ENSMUSG00000015702.
ENSMUST00000107183; ENSMUSP00000102801; ENSMUSG00000015702.
ENSMUST00000164406; ENSMUSP00000127424; ENSMUSG00000015702.
GeneIDi71790.
KEGGimmu:71790.
UCSCiuc008qjg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF437742 Genomic DNA. Translation: AAO37381.1.
AJ401160 mRNA. Translation: CAB95698.1. Frameshift.
AK010128 mRNA. Translation: BAB26719.1.
AK003395 mRNA. Translation: BAB22761.1.
BC062140 mRNA. Translation: AAH62140.1.
CCDSiCCDS50989.1.
RefSeqiNP_001078852.1. NM_001085383.1.
NP_076117.2. NM_023628.2.
XP_011238537.1. XM_011240235.1.
UniGeneiMm.218844.

3D structure databases

ProteinModelPortaliQ9JHQ0.
SMRiQ9JHQ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000015846.

PTM databases

PhosphoSitePlusiQ9JHQ0.

Proteomic databases

MaxQBiQ9JHQ0.
PaxDbiQ9JHQ0.
PRIDEiQ9JHQ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000015846; ENSMUSP00000015846; ENSMUSG00000015702.
ENSMUST00000107183; ENSMUSP00000102801; ENSMUSG00000015702.
ENSMUST00000164406; ENSMUSP00000127424; ENSMUSG00000015702.
GeneIDi71790.
KEGGimmu:71790.
UCSCiuc008qjg.1. mouse.

Organism-specific databases

CTDi8416.
MGIiMGI:1923711. Anxa9.

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
GeneTreeiENSGT00760000118972.
HOGENOMiHOG000158803.
HOVERGENiHBG061815.
InParanoidiQ9JHQ0.
KOiK17090.
OMAiTQRNPEH.
OrthoDBiEOG091G0B7B.
PhylomeDBiQ9JHQ0.
TreeFamiTF105452.

Miscellaneous databases

PROiQ9JHQ0.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000015702.
CleanExiMM_ANXA9.
ExpressionAtlasiQ9JHQ0. baseline and differential.
GenevisibleiQ9JHQ0. MM.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiIPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR009116. AnnexinXXXI.
[Graphical view]
PfamiPF00191. Annexin. 4 hits.
[Graphical view]
PRINTSiPR00196. ANNEXIN.
PR01812. ANNEXINXXXI.
SMARTiSM00335. ANX. 4 hits.
[Graphical view]
PROSITEiPS00223. ANNEXIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiANXA9_MOUSE
AccessioniPrimary (citable) accession number: Q9JHQ0
Secondary accession number(s): Q9CQS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: July 5, 2005
Last modified: November 2, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.