Q9JGT4 (VGLG_NCMV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycoprotein G

Gene names

Name:

G

Organism

Northern cereal mosaic virus (NCMV) [Complete proteome]

Taxonomic identifier

100880 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Mononegavirales › Rhabdoviridae › Cytorhabdovirus

Virus host

Hordeum vulgare (Barley) [TaxID: 4513]

Protein attributes

Sequence length	483 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane By similarity.
Subunit structure	Homotrimer. Interacts with matrix protein By similarity.
Subcellular location	Virion membrane; Single-pass type I membrane protein By similarity.
Post-translational modification	Glycosylatedby host. Glycosylation is crucial for glycoprotein export at the cell surface By similarity.
Sequence similarities	Belongs to the cytorhabdovirus glycoprotein family.

Ontologies

Keywords
Biological process	Host-virus interaction Viral attachment to host cell Virus entry into host cell
Cellular component	Membrane Viral envelope protein Virion
Domain	Signal Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	viral attachment to host cell Inferred from electronic annotation. Source: UniProtKB-KW viral entry into host cell Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW viral envelope Inferred from electronic annotation. Source: UniProtKB-KW virion membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 483	462	Glycoprotein G		PRO_0000299234
Regions
	Topological domain	22 – 442	421	Virion surface Potential
	Transmembrane	443 – 463	21	Helical; Potential
	Topological domain	464 – 483	20	Intravirion Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9JGT4 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 2A57C312429BF3A3	FASTA	483	54,118
	10 20 30 40 50 60 MQKLSLVWII TLSVSVITGD GLSILSCNKT DEVPTVTQCF KSCSDTILGE QVKVSILSQE 70 80 90 100 110 120 DPTSIVVGRC IWRIMKQSFT ETWTFSRLIS AKEITWEPAT TQECNGAFHN LCKNKAGCVS 130 140 150 160 170 180 EDLEIEPEFS WARTEIREVK HLSIETLTMS AYLHQGAGKV LIDGVAVPIS KKTHNNGDFT 190 200 210 220 230 240 YVWDDVPISE VCPWKHPISH LSCYKDKEDL DDIYCPSQGI SLVNYTKVDT SCPEQIYTDV 250 260 270 280 290 300 GGLVFKLGKV DFNDWYPYVI ESSDVAVKET ISSINMALKM RESVHCHQDC LEIRRRVTYV 310 320 330 340 350 360 DGFYYDPLPP AKCRLIGNCS VDSGSVTCNN GTLVWATCGG RRVWIDLKSG RDVKNAVCEK 370 380 390 400 410 420 GGRSRISKNQ FEGVLNEFHL NNSKFGNILR ANEIHSVILK DNEVMDFARV VKSASERSGN 430 440 450 460 470 480 FSEGTLINVR QLFRPMINFL RGIEHEIKVV AFSVLALIVG YIIIRIRTVT VAKAKSLESI AMI

References

[1]	"Complete nucleotide sequence of Northern cereal mosaic virus and its genome organization." Tanno F., Nakatsu A., Toriyama S., Kojima M. Arch. Virol. 145:1373-1384(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB030277 Genomic RNA. Translation: BAA95351.1.
RefSeq	NP_057961.1. NC_002251.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1457722.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

VGLG_NCMV

Accession

Primary (citable) accession number: Q9JGT4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 1, 2000
Last modified:	April 3, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program