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Q9JFD9

- PAP1_VACCT

UniProt

Q9JFD9 - PAP1_VACCT

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Protein

Poly(A) polymerase catalytic subunit

Gene
PAPL, TE1L
Organism
Vaccinia virus (strain Tian Tan) (VACV)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei202 – 2021 By similarity
Active sitei204 – 2041 By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. polynucleotide adenylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

mRNA processing, Transcription

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
Alternative name(s):
Poly(A) polymerase large subunit
Short name:
PAP-L
VP55
Gene namesi
Name:PAPL
ORF Names:TE1L
OrganismiVaccinia virus (strain Tian Tan) (VACV)
Taxonomic identifieri10253 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 479479Poly(A) polymerase catalytic subunitPRO_0000308941Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.

Structurei

3D structure databases

ProteinModelPortaliQ9JFD9.
SMRiQ9JFD9. Positions 12-479.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamiPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFiPIRSF015693. VAC-48L_nuct. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9JFD9-1 [UniParc]FASTAAdd to Basket

« Hide

MNRNPDQNTF PNITLKIIET YLGRVPSVNE YHMLKLQARN IQKITVFNKD    50
IFVSLVKKNK KRFFSDVDTS ASEIKDRILS YFSKQTQTYN IGKLFTIIEL 100
QSVLVTTYTD ILGVLTIKAP NVISSKISYN VTSMEELARD MLNSMNVAVI 150
DKAKVMGRHN VSSLVKNVNK LMEEYLRRHN KSCICYGSYS LYLINPNIRY 200
GDIDILQTNS RTFLIDLAFL IKFITGNNII LSKIPYLRNY MVIKDENDNH 250
IIDSFNIRQD TMNVVPKIFI DNIYIVDPTF QLLNMIKMKT QIDRLEDLSK 300
DPEKFNARMA TMLEYVRYTH GIVFDGTRNN MPMKCIIDEN NRIVTVTTKD 350
YFSFKKCLVY LDENVLSSDI LDLNADTSCD FESVTNSVYL IHDNIMYTYF 400
SNTILLSDKG KVHEISARGL CAHILLYQML TSGEYKQCLS DLLNSMMNRD 450
KIPIYSHTER DKKPGRHGFI NIEKDIIVF 479
Length:479
Mass (Da):55,534
Last modified:October 1, 2000 - v1
Checksum:i568CE717F07B48D4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF095689 Genomic DNA. Translation: AAF33911.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF095689 Genomic DNA. Translation: AAF33911.1 .

3D structure databases

ProteinModelPortali Q9JFD9.
SMRi Q9JFD9. Positions 12-479.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view ]
Pfami PF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genomic sequence of vaccinia virus (Tian Tan strain)."
    Jin Q., Hou Y.D., Cheng N.H., Yao E.M., Cheng S.X., Yang X.K., Jing D.Y., Yu W.H., Yuan J.S., Ma X.J.
    Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiPAP1_VACCT
AccessioniPrimary (citable) accession number: Q9JFD9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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