Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9J7Z2

- RDRP_PAV

UniProt

Q9J7Z2 - RDRP_PAV

Protein

RNA-directed RNA polymerase

Gene
N/A
Organism
Pariacoto virus (PaV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2.Curated

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation

    GO - Molecular functioni

    1. nucleotide binding Source: UniProtKB-KW
    2. RNA binding Source: InterPro
    3. RNA-directed RNA polymerase activity Source: UniProtKB-KW

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro
    2. viral RNA genome replication Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

    Keywords - Biological processi

    Viral RNA replication

    Keywords - Ligandi

    Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA-directed RNA polymerase (EC:2.7.7.48)
    Short name:
    RdRp
    Alternative name(s):
    RNA replicase
    Short name:
    Protein A
    OrganismiPariacoto virus (PaV)
    Taxonomic identifieri103782 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeAlphanodavirus
    Virus hostiSpodoptera eridania (Southern armyworm) [TaxID: 37547]

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 973973RNA-directed RNA polymerasePRO_0000222449Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ9J7Z2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini558 – 683126RdRp catalyticPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi962 – 9665Poly-Thr

    Sequence similaritiesi

    Belongs to the nodaviridae RNA polymerase family.Curated
    Contains 1 RdRp catalytic domain.PROSITE-ProRule annotation

    Family and domain databases

    InterProiIPR001205. RNA-dir_pol_C.
    IPR007094. RNA-dir_pol_PSvirus.
    [Graphical view]
    PfamiPF00680. RdRP_1. 1 hit.
    [Graphical view]
    PROSITEiPS50507. RDRP_SSRNA_POS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9J7Z2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEEHIPLPSQ YESPKALPPR VPSSRWLRSL RPRLANSCLA LKIRAHESLV    50
    KIRLCKPYDA QSRSKIIEKV IERRETRKTL AHQLKDLKLV PVARDHTHGR 100
    AAKFRTSANI WMNEAMRAAG YEPYNVSMSN HDIERGNRYF YFAKDLTIPY 150
    RNDPVSDNTG FVFCDVDYYA DMEKWMQHFK PMLLYTLVPE SLSYHCDDHS 200
    FHVNDDRVFF DVRGGASYSH QLWDYTGDTI CVRGKNKELL VFTIEQKCIQ 250
    GDPHRRIIFL EPAARVAWPF YKPMKVEVGL KRKCMTAGQV NVLYEPIDDK 300
    ISLSASGSRH TVETTGRTLA AITARMKNKT SPPMVADVER ILRDAGDKEA 350
    CVNAPILFEL IPEAKFRVNV VKTTATPTHF QPLGPLRTED GETCGHAVTT 400
    TLATAPALLP MRGVNSDVAT VNGRVKKPAN TVIPFKEYKE YASEFVEFLV 450
    PEPGVGHPWD TAAVREVQDN RQQKARINMV AATVSTHSSN RLKAFIKAEA 500
    YAATNDPRNI TTMAPELTLM MSCFTYAFKE KILYEQPWYG PGKTPKQVGR 550
    RLQSIAKHGT LESDYSRFDG SISEWLQKNV VKAAYMRFFK EHQRTEFQSW 600
    FSKVFMQMGT TTAGVRYEAG WGTRSGSPIT TDGNTMLNAF VVYCCYRKLC 650
    HTPAEAWRKL SQGALLTGDD AVLAHENGLE PALLDVVKNL GLKVEAKVNG 700
    PDDPVSFCGR IYPRLSDCIT SFQDPLRTIP KLHLTTNKGV SPEQAAANRA 750
    HGYLATDKAT PIIGTWARRV IELTGDLKVK GATREEQYKL SNAHQQLDPS 800
    LIETAMANIL GIDVGELKAL DKAVSEAKAL DQMPVVLGNC YKHKIEAVVG 850
    GEVVGPGPRV ETVEPNHEQS SGTPEVVPEM AGHSERRDKS SNPRPGGKAE 900
    GLSSKAGKPR VPTRPAADRK AAAGSGNRRG PTNGRRPIRD RAPRGGGRPN 950
    PGTTPPVSNS ETTTTTAVVH ASA 973
    Length:973
    Mass (Da):108,099
    Last modified:October 1, 2000 - v1
    Checksum:iC08835451D46EA1E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF171942 Genomic RNA. Translation: AAF71691.1.
    RefSeqiNP_620109.1. NC_003691.1.

    Genome annotation databases

    GeneIDi956347.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF171942 Genomic RNA. Translation: AAF71691.1 .
    RefSeqi NP_620109.1. NC_003691.1.

    3D structure databases

    ProteinModelPortali Q9J7Z2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 956347.

    Family and domain databases

    InterProi IPR001205. RNA-dir_pol_C.
    IPR007094. RNA-dir_pol_PSvirus.
    [Graphical view ]
    Pfami PF00680. RdRP_1. 1 hit.
    [Graphical view ]
    PROSITEi PS50507. RDRP_SSRNA_POS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization and construction of functional cDNA clones of Pariacoto virus, the first Alphanodavirus isolated outside Australasia."
      Johnson K.N., Zeddam J.-L., Ball L.A.
      J. Virol. 74:5123-5132(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiRDRP_PAV
    AccessioniPrimary (citable) accession number: Q9J7Z2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 16, 2002
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3