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Q9J5G5

- DUT_FOWPN

UniProt

Q9J5G5 - DUT_FOWPN

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Protein
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Gene
DUT, FPV038
Organism
Fowlpox virus (strain NVSL) (FPV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA By similarity.

Catalytic activityi

dUTP + H2O = dUMP + diphosphate.

Cofactori

Magnesium By similarity.

GO - Molecular functioni

  1. dUTP diphosphatase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. dUTP metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC:3.6.1.23)
Short name:
dUTPase
Alternative name(s):
dUTP pyrophosphatase
Gene namesi
Name:DUT
Ordered Locus Names:FPV038
OrganismiFowlpox virus (strain NVSL) (FPV)
Taxonomic identifieri928301 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeAvipoxvirus
Virus hostiVertebrata [TaxID: 7742]
ProteomesiUP000008597: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Deoxyuridine 5'-triphosphate nucleotidohydrolase
PRO_0000182947Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9J5G5.
SMRiQ9J5G5. Positions 8-143.

Family & Domainsi

Sequence similaritiesi

Belongs to the dUTPase family.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
InterProiIPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
IPR008181. dUTPase_1.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR00576. dut. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9J5G5-1 [UniParc]FASTAAdd to Basket

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MEEVTVYKIS DRAKLPYKQT SYSAGYDLYS AYDYVIEPMN KELIKTDIIL    50
KIPNGYYGRI APRSGLAYNY FIDVGAGVID SDYRGNVGVL LFNFGSTQFN 100
VCKGDRIAQI IFEKIAYPKI IEVTTLEEIN ITDRGNSGFG STGLK 145
Length:145
Mass (Da):16,253
Last modified:October 1, 2000 - v1
Checksum:i94CF5F6963B47D08
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF198100 Genomic DNA. Translation: AAF44382.1.
RefSeqiNP_039001.1. NC_002188.1.

Genome annotation databases

GeneIDi1486586.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF198100 Genomic DNA. Translation: AAF44382.1 .
RefSeqi NP_039001.1. NC_002188.1.

3D structure databases

ProteinModelPortali Q9J5G5.
SMRi Q9J5G5. Positions 8-143.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1486586.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
InterProi IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
IPR008181. dUTPase_1.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR00576. dut. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiDUT_FOWPN
AccessioniPrimary (citable) accession number: Q9J5G5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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