Reviewed, UniProtKB/Swiss-Prot Q9J5C7 (V093_FOWPV)

Names and origin

Protein names

Recommended name:
    Probable FAD-linked sulfhydryl oxidase FPV093
    EC=1.8.3.2

Gene names

Ordered Locus Names:	FPV093
ORF Names:	FPE10R

Organism

Fowlpox virus (FPV)

Taxonomic identifier

10261 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Avipoxvirus

Virus host

Vertebrata [TaxID: 7742]

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation By similarity.
Catalytic activity	4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O.
Cofactor	FAD By similarity.
Sequence similarities	Belongs to the poxviruses E10 family. Contains 1 ERV/ALR sulfhydryl oxidase domain.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	thiol oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Probable FAD-linked sulfhydryl oxidase FPV093		PRO_0000099467
Regions
	Domain	1 – 94	94	ERV/ALR sulfhydryl oxidase
Amino acid modifications
	Disulfide bond	41 ↔ 44		Redox-active Potential
Experimental info
	Sequence conflict	8	1	S → R in CAA11288. Ref.1
	Sequence conflict	11	1	W → G in CAA11288. Ref.1
	Sequence conflict	41	1	C → R in CAA11288. Ref.1
	Sequence conflict	68 – 69	2	FF → SS in CAA11288. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9J5C7-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 401A36D5E96AAAF8	FASTA	94	11,252
	10 20 30 40 50 60 MDPRYWGSSF WIVIFIIITK FKHDIETCKR HLYNICKALP CAECKDHALQ AIQKNNIMSS 70 80 90 NDINYIYFFF ISLYNNLVFN PERCIDIKKV KKLI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of the 4.3 kbp BamHI-N fragment of fowlpox virus FP9." Pollitt E., Skinner M.A., Heaphy S. Virus Genes 17:5-9(1998) [PubMed: 9778782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: FP-9 / Isolate HP-440.
[2]	"The genome of fowlpox virus." Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L. J. Virol. 74:3815-3831(2000) [PubMed: 10729156] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ223385 Genomic DNA. Translation: CAA11288.1. AF198100 Genomic DNA. Translation: AAF44437.1.
RefSeq	NP_039056.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1486641.
Enzyme and pathway databases
BRENDA	1.8.3.2. 288568.
Family and domain databases
InterPro	IPR017905. ERV/ALR_sulphydryl_oxidase. IPR006890. Sulfhydryl_Oase_FAD-link_ERV1. [Graphical view]
Pfam	PF04805. Pox_E10. 1 hit. [Graphical view]
PIRSF	PIRSF015696. VAC_E10R. 1 hit.
PROSITE	PS51324. ERV_ALR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

V093_FOWPV

Accession

Primary (citable) accession number: Q9J5C7
Secondary accession number(s): O72895

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 29, 2001
Last sequence update:	October 1, 2000
Last modified:	September 22, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Virus (Virus annotation project)