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Q9J5B8 (PAP1_FOWPN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
VP55
Gene names
Name:PAPL
Ordered Locus Names:FPV102
OrganismFowlpox virus (strain NVSL) (FPV) [Reference proteome]
Taxonomic identifier928301 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeAvipoxvirus
Virus hostVertebrata [TaxID: 7742]

Protein attributes

Sequence length472 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 472472Poly(A) polymerase catalytic subunit
PRO_0000099109

Sites

Active site1941 By similarity
Active site1961 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9J5B8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: ADDD6F39EC84DC22

FASTA47256,081
        10         20         30         40         50         60 
MERSRQVYYI INEYLGRHPS STEYQVLKHQ VEKISKINNF NKETFFFLLK KNKNKFFKDL 

        70         80         90        100        110        120 
ELSDDLLKKR IDEYFSKQKH AKRLGNLFAI MELQKILISS FTKTIGILTT KVPEYYHSTI 

       130        140        150        160        170        180 
KLEYSSMEKI ADDILDSYNV VEPSKEVKGR HKVSDLVGHV YKIMEEYLRR HSNSCLCYGS 

       190        200        210        220        230        240 
YSLHFLNNKI EYGDIDVLQT NARTFLINIA FLIKFITGRR IVLLKVPFLK NYVIMHDEET 

       250        260        270        280        290        300 
NHVMDTFNIR EKTMNMIPKI MIDNMYIVDP CIQLLNMIKM LSQIDRLEEL QAKFEKLSVR 

       310        320        330        340        350        360 
LGTLLEYTRY RYSIPLDSES ILEVRAKLDK DKRKITVDFK KYKLNYIKCY FYLDEVELKK 

       370        380        390        400        410        420 
FISKNSGLDE YEDFEAVTNS EYAIRNKTMY TYFSNTALMR SENEIHPITI NALTSHALLY 

       430        440        450        460        470 
HVITRKFYDD LLGDLVRSLM IVEKVPVFKI IPRDKKQGRH TIIDIEKDII FH 

« Hide

References

[1]"The genome of fowlpox virus."
Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.
J. Virol. 74:3815-3831(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Comparison of the genome sequence of FP9, an attenuated, tissue culture-adapted European fowlpox virus, with those of virulent American and European viruses."
Skinner M.A., Laidlaw S.M.
J. Gen. Virol. 85:305-322(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HP1-438 Munich.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF198100 Genomic DNA. Translation: AAF44446.1.
AJ581527 Genomic DNA. Translation: CAE52643.1.
RefSeqNP_039065.1. NC_002188.1.

3D structure databases

ProteinModelPortalQ9J5B8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1486650.

Phylogenomic databases

ProtClustDBPHA2996.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_FOWPN
AccessionPrimary (citable) accession number: Q9J5B8
Secondary accession number(s): Q70H53
Entry history
Integrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families