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Protein

Apoptin

Gene

VP3

Organism
Chicken anemia virus (isolate Australia/CAU269-7/2000) (CAV)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processApoptosis, Host-virus interaction, Inhibition of host mitotic exit by virus, Modulation of host cell cycle by virus

Names & Taxonomyi

Protein namesi
Recommended name:
Apoptin
Gene namesi
Name:VP3
OrganismiChicken anemia virus (isolate Australia/CAU269-7/2000) (CAV)
Taxonomic identifieri486492 [NCBI]
Taxonomic lineageiVirusesssDNA virusesAnelloviridaeGyrovirus
Virus hostiGallus gallus (Chicken) [TaxID: 9031]
Proteomesi
  • UP000007539 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003144751 – 121ApoptinAdd BLAST121

Expressioni

Inductioni

VP1 and VP2 are detected 12 hours post infection, while VP3 only after 24 hours.

Keywords - Developmental stagei

Early protein

Family & Domainsi

Sequence similaritiesi

Belongs to the gyrovirus apoptin family.Curated

Phylogenomic databases

OrthoDBiVOG090001AN

Family and domain databases

InterProiView protein in InterPro
IPR006858 CAV_VP3
PfamiView protein in Pfam
PF04771 CAV_VP3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9IZU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAHQEDTPP GPSTVFRPPT SSRPLETPHC REIRIGIAGI TVTLSLCGCA
60 70 80 90 100
NARVPTLRSA TADNSENTGF KNVPDLRTDQ PKPPSKKRSC DPSEYRVSEL
110 120
KESLITTTPS RPRTARRCIR L
Length:121
Mass (Da):13,310
Last modified:October 1, 2000 - v1
Checksum:i330B68FD98150DD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF227982 Genomic DNA Translation: AAF34788.1

Similar proteinsi

Entry informationi

Entry nameiVP3_CAVCA
AccessioniPrimary (citable) accession number: Q9IZU6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 1, 2000
Last modified: March 28, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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