Q9IY15 (Q9IY15_9HEPC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Genome polyprotein RuleBase RU000346
Organism	Hepatitis C virus EMBL AAF66332.1
Taxonomic identifier	11103 [NCBI]
Taxonomic lineage	Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Flaviviridae › Hepacivirus

Protein attributes

Sequence length	186 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

Ontologies

Keywords
Cellular component	Membrane Viral envelope protein RuleBase RU000346 Virion
Domain	Transmembrane RuleBase RU000346
Technical term	3D-structure PDB 4GAJ
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW viral envelope Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAF66332.1
	Non-terminal residue	186	1	EMBL AAF66332.1

Sequences

	Sequence		Length	Mass (Da)
	Q9IY15 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: FD6099D6CDB65BA3	FASTA	186	20,395
	10 20 30 40 50 60 MAWDMIMNWS PTTALVVSRL LRIPQAIVDM VAGAHWGVLA GLAYYSMVGN WAKVLIVMLL 70 80 90 100 110 120 FAGVDAGTYT TGGATGRSTY RLASLFTSGA SQNIQLINTN GSWHINRTAL NCNDSLQTGF 130 140 150 160 170 180 LAALFYTHKF NASGCPERMA SCRSIDQFAQ GWGPITYAVH RDLDQRPYCW HYPPRPCGIV PASQVC

References

[1]	"The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies." Farci P., Shimoda A., Coiana A., Diaz G., Peddis G., Melpolder J.C., Strazzera A., Chien D.Y., Munoz S.J., Balestrieri A., Purcell R.H., Alter H.J. Science 288:339-344(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Toward a hepatitis C virus vaccine: the structural basis of hepatitis C virus neutralization by AP33, a broadly neutralizing antibody." Potter J.A., Owsianka A.M., Jeffery N., Matthews D.J., Keck Z.Y., Lau P., Foung S.K., Taylor G.L., Patel A.H. J. Virol. 86:12923-12932(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.51 ANGSTROMS) OF 94-107.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF246033 Genomic RNA. Translation: AAF66332.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4GAJ	X-ray	2.51	P	94-107	[»]

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Organism-specific databases

euHCVdb

AF246033.

Family and domain databases

InterPro

IPR002519. HCV_env.
IPR002531. HCV_NS1.
[Graphical view]

Pfam

PF01539. HCV_env. 1 hit.
PF01560. HCV_NS1. 1 hit.
[Graphical view]

ProDom

PD001388. HCV_env. 1 hit.
[Graphical view] [Entries sharing at least one domain]

ProtoNet

Search...

Entry information

Entry name

Q9IY15_9HEPC

Accession

Primary (citable) accession number: Q9IY15

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)