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Q9IWA0 (RDRP_POLVP) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-directed RNA polymerase

EC=2.7.7.48
Alternative name(s):
Protein p84

Cleaved into the following chain:

  1. Protein p25
Gene names
ORF Names:ORF1
OrganismPothos latent virus (isolate Pigeonpea/India) (PoLV) [Reference proteome]
Taxonomic identifier652109 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeAureusvirus
Virus hostCajanus cajan (Pigeon pea) (Cajanus indicus) [TaxID: 3821]
Pothos [TaxID: 174212]

Protein attributes

Sequence length739 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNA-dependent RNA polymerase that plays an essential role in the virus replication Probable.

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Miscellaneous

Readthrough of the terminator UAG occurs at position 223.

Sequence similarities

Belongs to the tombusviridae RNA polymerase family.

Contains 1 RdRp catalytic domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 739739RNA-directed RNA polymerase
PRO_0000399488
Chain1 – 222222Protein p25
PRO_0000399489

Regions

Domain452 – 567116RdRp catalytic
Compositional bias119 – 1224Poly-Asp

Sequences

Sequence LengthMass (Da)Tools
Q9IWA0 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: D70C31F915221506

FASTA73983,699
        10         20         30         40         50         60 
MANWCMSVLM FSFVTVYTIV TSLGQGIRRG FRAIVDEVEN IYGDMCAGFK VALSKLSVSW 

        70         80         90        100        110        120 
IVVVGMIFVL NSLVVGLVPT LTMVAIIAAC VGAKYGGRVP RYIRAHVDRI RKSWEKGVDD 

       130        140        150        160        170        180 
DDCCAPLPET SLERVPTKLR PRLACKIAVR AIAKVGLLKR SEANSMVYQR VCLDVMESMK 

       190        200        210        220        230        240 
MRWHDRLVIL PQAVLACLER PEEVEEVMKA IEASCKGRFD VYXGCLLQHR GYNTAIISAI 

       250        260        270        280        290        300 
PDGVLLNHEG MVVRKGAPIT TERKWYSFAG YASTYEYIVH NSSLVNVCRG LVERVFCVVR 

       310        320        330        340        350        360 
DGKLQRPLRP KNNVFERKLG NVGRRISSIV GYCPAMTRSE FCESYSGTRR ATYERARLSL 

       370        380        390        400        410        420 
DVLPCTRKDA YLKTFVKAEK INITLKPDPA PRVIQPRDPR YNVEVGRYLK PLEPRLMKAI 

       430        440        450        460        470        480 
DKLWGEKTAI KGYTVEKVGE ILHQKSLRFK NPCFVGLDAS RFDQHCSRQA LEWEHSVYNA 

       490        500        510        520        530        540 
IFRDPYLSEL LTWQIDNVGT AYLKDGFVRY RVDGCRMSGD MNTSMGNYLI MSCLVYQFCK 

       550        560        570        580        590        600 
DIGIDASLAN CGDDCVLYLE KEDLPKLKAL PDWFGKMGYS MKVEKPVFTV EEIEFCQQHP 

       610        620        630        640        650        660 
VQLSRGYVMV RRPDVCLTKD LCVVRGGMTT ERLQRWLYAQ HDGGLALTGD CPVLGAFYRR 

       670        680        690        700        710        720 
FPSGESHGEL SEYSDAHKFK AGKQYGEINS LARYSFWLAF GITPDEQLAI ERDLMNWTPN 

       730 
VVPGSCDPRP TLLDYCSDN 

« Hide

References

[1]"Characterization of a virus from pigeonpea with affinities to species in the genus Aureusvirus, family Tombusviridae."
Lava Kumar P., Jones A.T., Sreenivasulu P., Fenton B., Reddy D.V.R.
Plant Dis. 85:208-215(2001) [AGRICOLA] [Europe PMC]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ243370 Genomic RNA. Translation: CAB59792.1.
AJ243370 Genomic RNA. Translation: CAB59793.1.
RefSeqNP_051030.1. NC_000939.1.
NP_051031.1. NC_000939.1.

3D structure databases

ProteinModelPortalQ9IWA0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1403813.
1403814.

Family and domain databases

InterProIPR007094. RNA-dir_pol_PSvirus.
IPR002166. RNA_pol_HCV.
IPR013707. Tombusvirus_p33.
[Graphical view]
PfamPF00998. RdRP_3. 1 hit.
PF08500. Tombus_P33. 1 hit.
[Graphical view]
PROSITEPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRDRP_POLVP
AccessionPrimary (citable) accession number: Q9IWA0
Secondary accession number(s): Q9QBU4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families