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Q9IB83

- PSB1B_CARAU

UniProt

Q9IB83 - PSB1B_CARAU

Protein

Proteasome subunit beta type-1-B

Gene

psmb1-B

Organism
Carassius auratus (Goldfish)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity By similarity.By similarity

    Catalytic activityi

    Cleavage of peptide bonds with very broad specificity.

    GO - Molecular functioni

    1. threonine-type endopeptidase activity Source: UniProtKB-KW

    GO - Biological processi

    1. proteolysis involved in cellular protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protease, Threonine protease

    Protein family/group databases

    MEROPSiT01.986.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Proteasome subunit beta type-1-B (EC:3.4.25.1)
    Alternative name(s):
    20S proteasome beta-6 subunit B
    Short name:
    B6-B
    Gene namesi
    Name:psmb1-B
    OrganismiCarassius auratus (Goldfish)
    Taxonomic identifieri7957 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeCarassius

    Subcellular locationi

    Cytoplasm PROSITE-ProRule annotation. Nucleus By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell
    3. proteasome core complex Source: UniProtKB

    Keywords - Cellular componenti

    Cytoplasm, Nucleus, Proteasome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 237237Proteasome subunit beta type-1-BPRO_0000148034Add
    BLAST

    Proteomic databases

    PRIDEiQ9IB83.

    Interactioni

    Subunit structurei

    The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ9IB83.
    SMRiQ9IB83. Positions 25-237.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase T1B family.PROSITE-ProRule annotation

    Phylogenomic databases

    HOVERGENiHBG000961.

    Family and domain databases

    Gene3Di3.60.20.10. 1 hit.
    InterProiIPR029055. Ntn_hydrolases_N.
    IPR016050. Proteasome_bsu_CS.
    IPR001353. Proteasome_sua/b.
    IPR023333. Proteasome_suB-type.
    [Graphical view]
    PfamiPF00227. Proteasome. 1 hit.
    [Graphical view]
    SUPFAMiSSF56235. SSF56235. 1 hit.
    PROSITEiPS00854. PROTEASOME_BETA_1. 1 hit.
    PS51476. PROTEASOME_BETA_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9IB83-1 [UniParc]FASTAAdd to Basket

    « Hide

    MISAQACGAN GKMKDYHYSG PVEHKFSPYA FNGGTVLAVA GEDFALVASD    50
    TRLSEGYSIH SRDSPKCYKL TDTTVIGCSG FHGDCLTLTK IIEARLKMYK 100
    HSNNKSMTSG AIAAMLSTIL YGRRFFPYYV YNIIGGLDEE GRGAVYSFDP 150
    VGSYQRDTYK AGGSASAMLQ PLLDNQIGFK NMENVEQVPL SQEKAVQLVK 200
    DVFISAAERD VYTGDALKIC IITKEGIREE IVPLRKD 237
    Length:237
    Mass (Da):26,002
    Last modified:October 1, 2000 - v1
    Checksum:i1E7C5B8A62789CC6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB035497 mRNA. Translation: BAA95592.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB035497 mRNA. Translation: BAA95592.1 .

    3D structure databases

    ProteinModelPortali Q9IB83.
    SMRi Q9IB83. Positions 25-237.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi T01.986.

    Proteomic databases

    PRIDEi Q9IB83.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG000961.

    Family and domain databases

    Gene3Di 3.60.20.10. 1 hit.
    InterProi IPR029055. Ntn_hydrolases_N.
    IPR016050. Proteasome_bsu_CS.
    IPR001353. Proteasome_sua/b.
    IPR023333. Proteasome_suB-type.
    [Graphical view ]
    Pfami PF00227. Proteasome. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56235. SSF56235. 1 hit.
    PROSITEi PS00854. PROTEASOME_BETA_1. 1 hit.
    PS51476. PROTEASOME_BETA_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of the goldfish 20S proteasome beta6 subunit bound to nuclear matrix."
      Tokumoto M., Yamaguchi A., Nagahama Y., Tokumoto T.
      FEBS Lett. 472:62-66(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Ovary.

    Entry informationi

    Entry nameiPSB1B_CARAU
    AccessioniPrimary (citable) accession number: Q9IB83
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 18, 2001
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3