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Q9IB83

- PSB1B_CARAU

UniProt

Q9IB83 - PSB1B_CARAU

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Protein

Proteasome subunit beta type-1-B

Gene
psmb1-B
Organism
Carassius auratus (Goldfish)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity By similarity.

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.

GO - Molecular functioni

  1. threonine-type endopeptidase activity Source: UniProtKB-KW

GO - Biological processi

  1. proteolysis involved in cellular protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Threonine protease

Protein family/group databases

MEROPSiT01.986.

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit beta type-1-B (EC:3.4.25.1)
Alternative name(s):
20S proteasome beta-6 subunit B
Short name:
B6-B
Gene namesi
Name:psmb1-B
OrganismiCarassius auratus (Goldfish)
Taxonomic identifieri7957 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeCarassius

Subcellular locationi

Cytoplasm By similarity. Nucleus By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
  3. proteasome core complex Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus, Proteasome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 237237Proteasome subunit beta type-1-BPRO_0000148034Add
BLAST

Proteomic databases

PRIDEiQ9IB83.

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ9IB83.
SMRiQ9IB83. Positions 25-237.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1B family.

Phylogenomic databases

HOVERGENiHBG000961.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiIPR029055. Ntn_hydrolases_N.
IPR016050. Proteasome_bsu_CS.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
[Graphical view]
PfamiPF00227. Proteasome. 1 hit.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiPS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9IB83-1 [UniParc]FASTAAdd to Basket

« Hide

MISAQACGAN GKMKDYHYSG PVEHKFSPYA FNGGTVLAVA GEDFALVASD    50
TRLSEGYSIH SRDSPKCYKL TDTTVIGCSG FHGDCLTLTK IIEARLKMYK 100
HSNNKSMTSG AIAAMLSTIL YGRRFFPYYV YNIIGGLDEE GRGAVYSFDP 150
VGSYQRDTYK AGGSASAMLQ PLLDNQIGFK NMENVEQVPL SQEKAVQLVK 200
DVFISAAERD VYTGDALKIC IITKEGIREE IVPLRKD 237
Length:237
Mass (Da):26,002
Last modified:October 1, 2000 - v1
Checksum:i1E7C5B8A62789CC6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB035497 mRNA. Translation: BAA95592.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB035497 mRNA. Translation: BAA95592.1 .

3D structure databases

ProteinModelPortali Q9IB83.
SMRi Q9IB83. Positions 25-237.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi T01.986.

Proteomic databases

PRIDEi Q9IB83.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG000961.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
InterProi IPR029055. Ntn_hydrolases_N.
IPR016050. Proteasome_bsu_CS.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
[Graphical view ]
Pfami PF00227. Proteasome. 1 hit.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
PROSITEi PS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification of the goldfish 20S proteasome beta6 subunit bound to nuclear matrix."
    Tokumoto M., Yamaguchi A., Nagahama Y., Tokumoto T.
    FEBS Lett. 472:62-66(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiPSB1B_CARAU
AccessioniPrimary (citable) accession number: Q9IB83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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