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Q9IA25 (HXA7_HETFR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Homeobox protein Hox-A7
Gene names
Name:HOXA7
OrganismHeterodontus francisci (Horn shark) (Cestracion francisci)
Taxonomic identifier7792 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiGaleomorphiiHeterodontoideaHeterodontiformesHeterodontidaeHeterodontus

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Antp homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
Gene Ontology (GO)
   Biological_processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 208208Homeobox protein Hox-A7
PRO_0000200077

Regions

DNA binding135 – 19460Homeobox
Motif124 – 1296Antp-type hexapeptide

Sequences

Sequence LengthMass (Da)Tools
Q9IA25 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 71B661AB78E064D0

FASTA20823,787
        10         20         30         40         50         60 
MSSSYYVNAL FPKYTAGTSV FQNASGFTEA TSCAFATNSQ RSSYGAGASA FPAPMAGLYN 

        70         80         90        100        110        120 
VNSAIYHGPT MYNTGYNLNS DSYNLRCSAL DQNIPVLCSD LSKQGCEKLD QTNVHPQAES 

       130        140        150        160        170        180 
NFRIYPWMRN AGPDRKRGRQ TYTRYQTLEL EKEFHFNRYL TRRRRIEIAH ALCLTERQIK 

       190        200 
IWFQNRRMKW KKETKAGSSS TTSEEKQE 

« Hide

References

[1]"Hox cluster genomics in the horn shark, Heterodontus francisci."
Kim C.B., Amemiya C., Bailey W., Kawasaki K., Mezey J., Miller W., Minoshima S., Shimizu N., Wagner G., Ruddle F.
Proc. Natl. Acad. Sci. U.S.A. 97:1655-1660(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF224262 Genomic DNA. Translation: AAF44645.1.

3D structure databases

ProteinModelPortalQ9IA25.
SMRQ9IA25. Positions 135-195.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG016849.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR017995. Homeobox_antennapedia.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00025. ANTENNAPEDIA.
PR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXA7_HETFR
AccessionPrimary (citable) accession number: Q9IA25
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries