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Q9IA15

- HXD11_HETFR

UniProt

Q9IA15 - HXD11_HETFR

Protein

Homeobox protein Hox-D11

Gene

HOXD11

Organism
Heterodontus francisci (Horn shark) (Cestracion francisci)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi193 – 25260HomeoboxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. multicellular organismal development Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Homeobox protein Hox-D11
    Gene namesi
    Name:HOXD11
    OrganismiHeterodontus francisci (Horn shark) (Cestracion francisci)
    Taxonomic identifieri7792 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiGaleomorphiiHeterodontoideaHeterodontiformesHeterodontidaeHeterodontus

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 265265Homeobox protein Hox-D11PRO_0000200235Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ9IA15.
    SMRiQ9IA15. Positions 190-255.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Abd-B homeobox family.Curated
    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Phylogenomic databases

    HOVERGENiHBG052048.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR021918. DUF3528.
    IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view]
    PfamiPF12045. DUF3528. 1 hit.
    PF00046. Homeobox. 1 hit.
    [Graphical view]
    PRINTSiPR00024. HOMEOBOX.
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9IA15-1 [UniParc]FASTAAdd to Basket

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    MYLPSCTYYV SAPDFSSVST FLPPTTSCQM TFPYSSNLAQ VQPVRELSFR    50
    DYGLEHPTKW HYRSNYAPYC SAEEIMHRDY IQPPTRTGML FKNDTVYSQR 100
    GSSNPSCNFY TTVGRNGILP QGFDQFFETA YGISDSSNYE QLTEKSVSTC 150
    QSITASEKVS SGQEKESATE KSTVESSGTS ATEKNSLSTA LRCRKKRCPY 200
    TKYQIRELER EFFFNVYINK EKRLQLSRML NLTDRQVKIW FQNRRMKEKK 250
    LSRDRLHFFT GNPLL 265
    Length:265
    Mass (Da):30,722
    Last modified:October 1, 2000 - v1
    Checksum:iCC1AF6B48A91E28F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF224263 Genomic DNA. Translation: AAF44635.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF224263 Genomic DNA. Translation: AAF44635.1 .

    3D structure databases

    ProteinModelPortali Q9IA15.
    SMRi Q9IA15. Positions 190-255.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG052048.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR021918. DUF3528.
    IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view ]
    Pfami PF12045. DUF3528. 1 hit.
    PF00046. Homeobox. 1 hit.
    [Graphical view ]
    PRINTSi PR00024. HOMEOBOX.
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiHXD11_HETFR
    AccessioniPrimary (citable) accession number: Q9IA15
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2001
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. Vertebrate homeotic Hox proteins
      Nomenclature of vertebrate homeotic Hox proteins and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3