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Protein
Submitted name:

Bax

Gene

baxa

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • positive regulation of apoptotic process Source: ZFIN
  • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: ZFIN
  • response to cadmium ion Source: ZFIN
  • response to methylmercury Source: ZFIN

Enzyme and pathway databases

ReactomeiR-DRE-114294. Activation, translocation and oligomerization of BAX.
R-DRE-6804114. TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.

Names & Taxonomyi

Protein namesi
Submitted name:
BaxImported
Submitted name:
Baxa proteinImported
Submitted name:
Bcl2-associated X protein, aImported
Gene namesi
Name:baxaImported
Synonyms:baxImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 3

Organism-specific databases

ZFINiZDB-GENE-000511-6. baxa.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei171 – 189HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSDARG00000020623.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000023687.

Structurei

3D structure databases

SMRiQ9I9N4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWQJ. Eukaryota.
ENOG4112738. LUCA.
GeneTreeiENSGT00730000111112.
HOGENOMiHOG000095178.
HOVERGENiHBG003606.
KOiK02159.
OMAiVINWIRE.
OrthoDBiEOG091G0YWR.
TreeFamiTF315834.

Family and domain databases

InterProiView protein in InterPro
IPR026304. BAX.
IPR002475. Bcl2-like.
IPR026298. Blc2_fam.
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF52. PTHR11256:SF52. 1 hit.
PfamiView protein in Pfam
PF00452. Bcl-2. 1 hit.
PRINTSiPR01862. BCL2FAMILY.
SUPFAMiSSF56854. SSF56854. 1 hit.
PROSITEiView protein in PROSITE
PS50062. BCL2_FAMILY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I9N4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPSGGGDT GSGNDQILDL GAALLNNFVY ERVRRHGDRD AEVTRSQLGG
60 70 80 90 100
VELCDPSHKR LAQCLQQIGD ELDGNAQLQS MLNNSNLQPT QDVFIRVARE
110 120 130 140 150
IFSDGKFNWG RVVALFYFAC RLVIKAISTR VPDIIRTIIS WTMSYIQEHV
160 170 180 190
INWIREQGGW DGIRSYFGTP TWQTVGVFLA GVITTALVIR KM
Length:192
Mass (Da):21,401
Last modified:October 1, 2000 - v1
Checksum:i8A71A630A56FDC32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR388062 Genomic DNA. No translation available.
AF231015 Genomic DNA. Translation: AAF66960.1.
BC055592 mRNA. Translation: AAH55592.1.
BC164990 mRNA. Translation: AAI64990.1.
RefSeqiNP_571637.1. NM_131562.2.
UniGeneiDr.78968.

Genome annotation databases

EnsembliENSDART00000011691; ENSDARP00000023687; ENSDARG00000020623.
GeneIDi58081.
KEGGidre:58081.

Similar proteinsi

Entry informationi

Entry nameiQ9I9N4_DANRE
AccessioniPrimary (citable) accession number: Q9I9N4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: September 27, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported