pin1

Functionⁱ

Catalytic activityⁱ

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotation

GO - Molecular functionⁱ

peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-UniRule

Complete GO annotation...

Keywordsⁱ

Molecular function	Isomerase, RotamasePROSITE-ProRule annotation

Molecular function

Isomerase, RotamasePROSITE-ProRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Gene namesⁱ	Name:pin1Imported Synonyms:Pin1Imported ORF Names:XELAEV_18018988mgImported
Organismⁱ	Xenopus laevis (African clawed frog)Imported
Taxonomic identifierⁱ	8355 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus
Proteomesⁱ	UP000186698 Componentⁱ: Chromosome 3l

Organism-specific databases

Xenbaseⁱ	XB-GENE-6254024. pin1.

Xenbaseⁱ

XB-GENE-6254024. pin1.

Interactionⁱ

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-35667N.
IntActⁱ	Q9I9K6. 1 interactor.
Molecular INTeraction database More...MINTⁱ	MINT-4051741.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	5 – 39	WWInterPro annotationAdd BLAST		35
Domainⁱ	48 – 159	PpiCInterPro annotationAdd BLAST		112

Phylogenomic databases

HOVERGENⁱ	HBG002101.
KEGG Orthology (KO) More...KOⁱ	K09578.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000297. PPIase_PpiC. IPR023058. PPIase_PpiC_CS. IPR001202. WW_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00639. Rotamase. 1 hit. PF00397. WW. 1 hit.
SMARTⁱ	View protein in SMART SM00456. WW. 1 hit.
SUPFAMⁱ	SSF51045. SSF51045. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01096. PPIC_PPIASE_1. 1 hit. PS50198. PPIC_PPIASE_2. 1 hit. PS01159. WW_DOMAIN_1. 1 hit. PS50020. WW_DOMAIN_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9I9K6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MADEEKLPPG WEKRMSRSSG RVYYFNHMTN ASQWERPIAG GKNGQGEPGK 
        60         70         80         90        100
VRCSHLLVKH NQSRRPSSWR QDKITRSKDE ALELINGYIQ KMKSGDEDFE 
       110        120        130        140        150
SLASQFSDCS SAKAGGDLGS FGKGAMQKPF EDASFALRPG EMSGPVFTDS 

GIHIILRTE

Length:159

Mass (Da):17,671

Last modified:October 1, 2000 - v1

Checksum:ⁱ4E54F66F16C9DF1C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF239760 mRNA. Translation: AAF43897.1. CM004470 Genomic DNA. Translation: OCT90376.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001084236.1. NM_001090767.1.
UniGeneⁱ	Xl.613.

Genome annotation databases

GeneIDⁱ	399385.
KEGGⁱ	xla:399385.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF239760 mRNA. Translation: AAF43897.1. CM004470 Genomic DNA. Translation: OCT90376.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001084236.1. NM_001090767.1.
UniGeneⁱ	Xl.613.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-35667N.
IntActⁱ	Q9I9K6. 1 interactor.
Molecular INTeraction database More...MINTⁱ	MINT-4051741.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	399385.
KEGGⁱ	xla:399385.

Organism-specific databases

CTDⁱ	399385.
Xenbaseⁱ	XB-GENE-6254024. pin1.

Phylogenomic databases

HOVERGENⁱ	HBG002101.
KEGG Orthology (KO) More...KOⁱ	K09578.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000297. PPIase_PpiC. IPR023058. PPIase_PpiC_CS. IPR001202. WW_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00639. Rotamase. 1 hit. PF00397. WW. 1 hit.
SMARTⁱ	View protein in SMART SM00456. WW. 1 hit.
SUPFAMⁱ	SSF51045. SSF51045. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01096. PPIC_PPIASE_1. 1 hit. PS50198. PPIC_PPIASE_2. 1 hit. PS01159. WW_DOMAIN_1. 1 hit. PS50020. WW_DOMAIN_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q9I9K6_XENLA
Accessionⁱ	Q9I9K6Primary (citable) accession number: Q9I9K6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 1, 2000
	Last sequence update:	October 1, 2000
	Last modified:	June 7, 2017
	This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q9I9K6 (Q9I9K6_XENLA)

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Peptidyl-prolyl cis-trans isomerase

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Functionⁱ

Catalytic activityⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9I9K6 (Q9I9K6_XENLA)

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Peptidyl-prolyl cis-trans isomerase

pin1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Interactionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ