Q9I9I2 (Q9I9I2_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Protein Wnt RuleBase RU003503

Gene names

Name:

wnt11r EMBL AAF64231.1 Ensembl ENSDARP00000090653

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAF64231.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Ligand for members of the frizzled family of seven transmembrane receptors By similarity. RuleBase RU003500
Subcellular location	Secreted › extracellular space › extracellular matrix By similarity RuleBase RU003500.
Sequence similarities	Belongs to the Wnt family. RuleBase RU003500

Ontologies

Keywords
Biological process	Wnt signaling pathway SAAS SAAS005817 RuleBase RU003500
Cellular component	Extracellular matrix SAAS SAAS005817 Secreted
Molecular function	Developmental protein SAAS SAAS005817 RuleBase RU003500
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	Wnt receptor signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW anterior/posterior pattern specification Inferred from Biological aspect of Ancestor. Source: RefGenome artery morphogenesis Inferred from Biological aspect of Ancestor. Source: RefGenome axis specification Inferred from Biological aspect of Ancestor. Source: RefGenome bone mineralization Inferred from Biological aspect of Ancestor. Source: RefGenome cell migration involved in gastrulation Inferred from mutant phenotype. Source: ZFIN endoderm development Inferred from Biological aspect of Ancestor. Source: RefGenome negative regulation of canonical Wnt receptor signaling pathway Inferred from Biological aspect of Ancestor. Source: RefGenome osteoblast differentiation Inferred from Biological aspect of Ancestor. Source: RefGenome outflow tract morphogenesis Inferred from Biological aspect of Ancestor. Source: RefGenome palate development Inferred from Biological aspect of Ancestor. Source: RefGenome positive regulation of transforming growth factor beta2 production Inferred from Biological aspect of Ancestor. Source: RefGenome tight junction assembly Inferred from Biological aspect of Ancestor. Source: RefGenome ventricular septum morphogenesis Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular component	extracellular space Inferred from Biological aspect of Ancestor. Source: RefGenome plasma membrane Inferred from Biological aspect of Ancestor. Source: RefGenome proteinaceous extracellular matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	G-protein coupled receptor binding Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9I9I2 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 15938023BC411F47	FASTA	352	39,484
	10 20 30 40 50 60 MKRTFPSLPL CLLTFLLLSQ QCTGIRWLAL SQTAQHINKT QHCKTLPGLV SSQAQLCRSN 70 80 90 100 110 120 LELMQTIIQA AREVKKVCQK TFTDMRWNCS SIDGPKFLPD LERGTRESAF VYALSAAAIS 130 140 150 160 170 180 HTIARACTSG DLRLCSCGPI PGEIPEPGYR WGGCADNIHY GLLMGSKFSD APMKMKKKSG 190 200 210 220 230 240 SHANKLMHLH NSEVGRQALR DALVMKCKCH GVSGSCSIRT CWRGLLDLKD IAIDLKTKYL 250 260 270 280 290 300 SATKVVHRPM GTRKQLVPKD IDIRPVRENE LVYLQSSPDY CMKNDKLGSF GTQDRQCNKT 310 320 330 340 350 SSGSDSCDLM CCGRGYNPYT ERVVERCHCK YHWCCYVTCK KCDKTVEKYV CK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney EMBL AAH66498.1.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000090653.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000090653.
[4]	"Zebrafish wnt11r cDNA sequence." Lekven A.C., Riggleman R., Moon R.T. Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU467651 Genomic DNA. No translation available. AF249266 mRNA. Translation: AAF64231.1. BC066498 mRNA. Translation: AAH66498.1.
IPI	IPI00508897.
RefSeq	NP_571151.1. NM_131076.2.
UniGene	Dr.76466.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9I9I2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000099880; ENSDARP00000090653; ENSDARG00000014796.
GeneID	30283.
KEGG	dre:30283.
Organism-specific databases
CTD	30283.
ZFIN	ZDB-GENE-980526-249. wnt11r.
Phylogenomic databases
eggNOG	fiNOG11575.
GeneTree	ENSGT00560000076960.
HOGENOM	HBG446188.
HOVERGEN	HBG001595.
InParanoid	Q9I9I2.
OMA	ELIYLQS.
OrthoDB	EOG4FR0RT.
Gene expression databases
ArrayExpress	Q9I9I2.
Bgee	Q9I9I2.
Family and domain databases
InterPro	IPR005817. Wnt. IPR018161. Wnt_grthfactor_CS. [Graphical view]
KO	K01384.
PANTHER	PTHR12027. Wnt. 1 hit.
Pfam	PF00110. wnt. 1 hit. [Graphical view]
PRINTS	PR01349. WNTPROTEIN.
SMART	SM00097. WNT1. 1 hit. [Graphical view]
PROSITE	PS00246. WNT1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9I9I2_DANRE

Accession

Primary (citable) accession number: Q9I9I2

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)