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Q9I9E8

- Q9I9E8_DANRE

UniProt

Q9I9E8 - Q9I9E8_DANRE

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Protein
Submitted name: E4tf1-60 transcription factor
Gene
gabpa, e4tf
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotation

Enzyme and pathway databases

ReactomeiREACT_220389. Transcriptional activation of mitochondrial biogenesis.

Names & Taxonomyi

Protein namesi
Submitted name:
E4tf1-60 transcription factorImported
Submitted name:
GA-binding protein transcription factor, alpha subunitImported
Submitted name:
Gabpa proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:gabpaImported
Synonyms:e4tfImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-011010-2. gabpa.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the ETS family.UniRule annotation
Contains 1 ETS DNA-binding domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00750000117307.
HOGENOMiHOG000285952.
HOVERGENiHBG051687.
InParanoidiQ9I9E8.
KOiK09441.
OMAiGIPYDPV.
TreeFamiTF350537.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.150.50. 1 hit.
InterProiIPR000418. Ets_dom.
IPR024668. GABP_asu_N.
IPR003118. Pointed_dom.
IPR013761. SAM/pointed.
IPR016312. TF_GA-bd_asu.
IPR029071. Ubiquitin-rel_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00178. Ets. 1 hit.
PF11620. GABP-alpha. 1 hit.
PF02198. SAM_PNT. 1 hit.
[Graphical view]
PIRSFiPIRSF001703. GABP_alpha. 1 hit.
PRINTSiPR00454. ETSDOMAIN.
SMARTiSM00413. ETS. 1 hit.
SM00251. SAM_PNT. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
PS51433. PNT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9I9E8-1 [UniParc]FASTAAdd to Basket

« Hide

MSKSETEEMI EIEIDGREKQ ECLEEGIEEQ TITAAELITQ DIDINEPIGN    50
LKKLLEPRLQ IPLDGYDICL QDIQLHPDHS LFDQGVKTDG TVQLSVQIVT 100
KPGEEKLNIL EIVKPVETVE VVIDPDAAAG EEAHLVEDGQ VIAVERAALP 150
DETSEQVTRW AAALEGYRKE QVRLNIPYDP VQWTADQVIH WAVWVMKEFG 200
IDEMEVGGIH IPGRQLCGFS QEEFLQRVPS GEILWSHLEL LRKYVLASQD 250
QSQEATVTID QPVQIIPAPV QQATPTAIKV MKHNKTPRAP RISGEERSSP 300
GNRTGNNGQI QLWQFLLELL TDKDSRDCIS WVGEEGEFKL NQPELVAQKW 350
GQRKNKPTMN YEKLSRALRY YYDGDMISKV QGKRFVYKFV CDLRTLIGYS 400
AAELNNLVTE CEQKKLARVQ LQGLGQPVNT VTLATATGQP VTTVTLAAAA 450
LDKDS 455
Length:455
Mass (Da):51,045
Last modified:October 1, 2000 - v1
Checksum:iDC23A5927F566E7F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR759841 Genomic DNA. No translation available.
AF257741 mRNA. Translation: AAF71747.1.
BC055494 mRNA. Translation: AAH55494.1.
BC066501 mRNA. Translation: AAH66501.1.
BC165340 mRNA. Translation: AAI65340.1.
RefSeqiNP_571662.1. NM_131587.1.
XP_005167909.1. XM_005167852.1.
XP_005167910.1. XM_005167853.1.
UniGeneiDr.77675.

Genome annotation databases

EnsembliENSDART00000100700; ENSDARP00000091473; ENSDARG00000069289.
ENSDART00000100701; ENSDARP00000091474; ENSDARG00000069289.
GeneIDi58110.
KEGGidre:58110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR759841 Genomic DNA. No translation available.
AF257741 mRNA. Translation: AAF71747.1 .
BC055494 mRNA. Translation: AAH55494.1 .
BC066501 mRNA. Translation: AAH66501.1 .
BC165340 mRNA. Translation: AAI65340.1 .
RefSeqi NP_571662.1. NM_131587.1.
XP_005167909.1. XM_005167852.1.
XP_005167910.1. XM_005167853.1.
UniGenei Dr.77675.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000100700 ; ENSDARP00000091473 ; ENSDARG00000069289 .
ENSDART00000100701 ; ENSDARP00000091474 ; ENSDARG00000069289 .
GeneIDi 58110.
KEGGi dre:58110.

Organism-specific databases

CTDi 2551.
ZFINi ZDB-GENE-011010-2. gabpa.

Phylogenomic databases

GeneTreei ENSGT00750000117307.
HOGENOMi HOG000285952.
HOVERGENi HBG051687.
InParanoidi Q9I9E8.
KOi K09441.
OMAi GIPYDPV.
TreeFami TF350537.

Enzyme and pathway databases

Reactomei REACT_220389. Transcriptional activation of mitochondrial biogenesis.

Miscellaneous databases

NextBioi 20892362.
PROi Q9I9E8.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
1.10.150.50. 1 hit.
InterProi IPR000418. Ets_dom.
IPR024668. GABP_asu_N.
IPR003118. Pointed_dom.
IPR013761. SAM/pointed.
IPR016312. TF_GA-bd_asu.
IPR029071. Ubiquitin-rel_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00178. Ets. 1 hit.
PF11620. GABP-alpha. 1 hit.
PF02198. SAM_PNT. 1 hit.
[Graphical view ]
PIRSFi PIRSF001703. GABP_alpha. 1 hit.
PRINTSi PR00454. ETSDOMAIN.
SMARTi SM00413. ETS. 1 hit.
SM00251. SAM_PNT. 1 hit.
[Graphical view ]
SUPFAMi SSF47769. SSF47769. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEi PS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
PS51433. PNT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "An e4tf cDNA from Zebrafish (Danio rerio)."
    Slavov D.B., Gardiner K.
    Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Whole bodyImported.
  3. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: KidneyImported.
  4. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescueImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  6. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ9I9E8_DANRE
AccessioniPrimary (citable) accession number: Q9I9E8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: September 3, 2014
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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