Q9I9E8 (Q9I9E8_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
E4tf1-60 transcription factor EMBL AAF71747.1

Submitted name:
GA-binding protein transcription factor, alpha subunit EMBL AAH66501.1
Submitted name:
Gabpa protein EMBL AAH55494.1
Submitted name:
Uncharacterized protein Ensembl ENSDARP00000091473 Ensembl ENSDARP00000091474

Gene names

Name:	gabpa ZFIN ZDB-GENE-011010-2 Ensembl ENSDARP00000091473 Ensembl ENSDARP00000091474
Synonyms:	e4tf ZFIN ZDB-GENE-000616-12 EMBL AAF71747.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the ETS family. RuleBase RU004019 Contains 1 ETS DNA-binding domain. RuleBase RU004019

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU004018
Ligand	DNA-binding RuleBase RU004018
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9I9E8 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: DC23A5927F566E7F	FASTA	455	51,045
	10 20 30 40 50 60 MSKSETEEMI EIEIDGREKQ ECLEEGIEEQ TITAAELITQ DIDINEPIGN LKKLLEPRLQ 70 80 90 100 110 120 IPLDGYDICL QDIQLHPDHS LFDQGVKTDG TVQLSVQIVT KPGEEKLNIL EIVKPVETVE 130 140 150 160 170 180 VVIDPDAAAG EEAHLVEDGQ VIAVERAALP DETSEQVTRW AAALEGYRKE QVRLNIPYDP 190 200 210 220 230 240 VQWTADQVIH WAVWVMKEFG IDEMEVGGIH IPGRQLCGFS QEEFLQRVPS GEILWSHLEL 250 260 270 280 290 300 LRKYVLASQD QSQEATVTID QPVQIIPAPV QQATPTAIKV MKHNKTPRAP RISGEERSSP 310 320 330 340 350 360 GNRTGNNGQI QLWQFLLELL TDKDSRDCIS WVGEEGEFKL NQPELVAQKW GQRKNKPTMN 370 380 390 400 410 420 YEKLSRALRY YYDGDMISKV QGKRFVYKFV CDLRTLIGYS AAELNNLVTE CEQKKLARVQ 430 440 450 LQGLGQPVNT VTLATATGQP VTTVTLAAAA LDKDS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"An e4tf cDNA from Zebrafish (Danio rerio)." Slavov D.B., Gardiner K. Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Whole body EMBL AAH55494.1.
[3]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney EMBL AAH66501.1.
[4]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000091473 Ensembl ENSDARP00000091474.
[5]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000091473 Ensembl ENSDARP00000091474.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR759841 Genomic DNA. No translation available. AF257741 mRNA. Translation: AAF71747.1. BC055494 mRNA. Translation: AAH55494.1. BC066501 mRNA. Translation: AAH66501.1.
IPI	IPI00482294.
RefSeq	NP_571662.1. NM_131587.1.
UniGene	Dr.77675.
3D structure databases
HSSP	HSSP built from PDB template 1AWC based on UniProtKB Q00422.
SMR	Q9I9E8. Positions 35-120, 162-248, 310-419.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000100700; ENSDARP00000091473; ENSDARG00000069289. ENSDART00000100701; ENSDARP00000091474; ENSDARG00000069289.
GeneID	58110.
KEGG	dre:58110.
Organism-specific databases
CTD	2551.
ZFIN	ZDB-GENE-011010-2. gabpa.
Phylogenomic databases
GeneTree	ENSGT00700000104086.
HOGENOM	HOG000285952.
HOVERGEN	HBG051687.
InParanoid	Q9I9E8.
KO	K09441.
Family and domain databases
Gene3D	1.10.10.10. 1 hit. 1.10.150.50. 1 hit.
InterPro	IPR000418. Ets_dom. IPR024668. GABP_asu_N. IPR003118. Pointed_dom. IPR013761. SAM/pointed. IPR016312. TF_GA-bd_asu. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00178. Ets. 1 hit. PF11620. GABP-alpha. 1 hit. PF02198. SAM_PNT. 1 hit. [Graphical view]
PIRSF	PIRSF001703. GABP_alpha. 1 hit.
PRINTS	PR00454. ETSDOMAIN.
SMART	SM00413. ETS. 1 hit. SM00251. SAM_PNT. 1 hit. [Graphical view]
SUPFAM	SSF47769. SAM_homology. 1 hit.
PROSITE	PS00345. ETS_DOMAIN_1. 1 hit. PS00346. ETS_DOMAIN_2. 1 hit. PS50061. ETS_DOMAIN_3. 1 hit. PS51433. PNT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20892362.

Entry information

Entry name

Q9I9E8_DANRE

Accession

Primary (citable) accession number: Q9I9E8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 105 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)