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Protein
Submitted name:

E4tf1-60 transcription factor

Gene

gabpa

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-2151201. Transcriptional activation of mitochondrial biogenesis.

Names & Taxonomyi

Protein namesi
Submitted name:
E4tf1-60 transcription factorImported
Submitted name:
GA-binding protein transcription factor, alpha subunitImported
Submitted name:
Gabpa proteinImported
Gene namesi
Name:gabpaImported
Synonyms:e4tfImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-011010-2. gabpa.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000069289.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000091474.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini162 – 245PNTInterPro annotationAdd BLAST84
Domaini310 – 390ETSInterPro annotationAdd BLAST81

Sequence similaritiesi

Belongs to the ETS family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3806. Eukaryota.
ENOG410Z0ZF. LUCA.
GeneTreeiENSGT00760000118907.
HOGENOMiHOG000285952.
HOVERGENiHBG051687.
KOiK09441.
OMAiVQINVQI.
OrthoDBiEOG091G0EXE.
TreeFamiTF350537.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000418. Ets_dom.
IPR024668. GABP_asu_N.
IPR003118. Pointed_dom.
IPR013761. SAM/pointed.
IPR016312. TF_GA-bd_asu.
IPR029071. Ubiquitin-rel_dom.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00178. Ets. 1 hit.
PF11620. GABP-alpha. 1 hit.
PF02198. SAM_PNT. 1 hit.
PIRSFiPIRSF001703. GABP_alpha. 1 hit.
PRINTSiPR00454. ETSDOMAIN.
SMARTiView protein in SMART
SM00413. ETS. 1 hit.
SM00251. SAM_PNT. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF47769. SSF47769. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiView protein in PROSITE
PS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
PS51433. PNT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I9E8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKSETEEMI EIEIDGREKQ ECLEEGIEEQ TITAAELITQ DIDINEPIGN
60 70 80 90 100
LKKLLEPRLQ IPLDGYDICL QDIQLHPDHS LFDQGVKTDG TVQLSVQIVT
110 120 130 140 150
KPGEEKLNIL EIVKPVETVE VVIDPDAAAG EEAHLVEDGQ VIAVERAALP
160 170 180 190 200
DETSEQVTRW AAALEGYRKE QVRLNIPYDP VQWTADQVIH WAVWVMKEFG
210 220 230 240 250
IDEMEVGGIH IPGRQLCGFS QEEFLQRVPS GEILWSHLEL LRKYVLASQD
260 270 280 290 300
QSQEATVTID QPVQIIPAPV QQATPTAIKV MKHNKTPRAP RISGEERSSP
310 320 330 340 350
GNRTGNNGQI QLWQFLLELL TDKDSRDCIS WVGEEGEFKL NQPELVAQKW
360 370 380 390 400
GQRKNKPTMN YEKLSRALRY YYDGDMISKV QGKRFVYKFV CDLRTLIGYS
410 420 430 440 450
AAELNNLVTE CEQKKLARVQ LQGLGQPVNT VTLATATGQP VTTVTLAAAA

LDKDS
Length:455
Mass (Da):51,045
Last modified:October 1, 2000 - v1
Checksum:iDC23A5927F566E7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR759841 Genomic DNA. No translation available.
AF257741 mRNA. Translation: AAF71747.1.
BC055494 mRNA. Translation: AAH55494.1.
BC066501 mRNA. Translation: AAH66501.1.
BC165340 mRNA. Translation: AAI65340.1.
RefSeqiNP_001315341.1. NM_001328412.1.
NP_571662.1. NM_131587.2.
XP_005167910.1. XM_005167853.3.
UniGeneiDr.77675.

Genome annotation databases

EnsembliENSDART00000100700; ENSDARP00000091473; ENSDARG00000069289.
ENSDART00000100701; ENSDARP00000091474; ENSDARG00000069289.
GeneIDi58110.
KEGGidre:58110.

Similar proteinsi

Entry informationi

Entry nameiQ9I9E8_DANRE
AccessioniPrimary (citable) accession number: Q9I9E8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: September 27, 2017
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported