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Protein
Submitted name:

Peroxisome proliferator-activated receptor alpha

Gene

PPARalpha

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi99 – 173Nuclear receptorPROSITE-ProRule annotationAdd BLAST75

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Peroxisome proliferator-activated receptor alphaImported
Gene namesi
Name:PPARalphaImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini99 – 173Nuclear receptorInterPro annotationAdd BLAST75

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IMDD. Eukaryota.
ENOG410ZRFG. LUCA.
HOVERGENiHBG106004.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR003074. 1Cnucl_rcpt.
IPR003076. 1Cnucl_rcpt_A.
IPR035500. NHR_like_dom_sf.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01288. PROXISOMEPAR.
PR01289. PROXISOMPAAR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9I8W4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDTENQLYP LTPLEEDDIG SPLSGEFLQD MENIQDISQS LGDDSSGALS
60 70 80 90 100
LTEFQSLGNG PGSDGSVITD TLSPASSPSS INFATAPGSI DESPSGAENI
110 120 130 140 150
ECRICGDKAS GYHYGVHACE GCKGFFRRTI RLKLIYDKCD RNCKIQKKNR
160 170 180 190 200
NKCQYCRFQK CLSVGMSHNA IRFGRMPRSE KAKLKAEILT GENYVEDSEM
210 220 230 240 250
ADLKSLAKRI HDAYLKNFNM NKVKARVILA GKTNNNPPFV IHDMDTLCMA
260 270 280 290 300
EKTLVAKLVA NGIQNKEAEV RIFHCCQCTS VETVTELTEF AKSIPGFSNL
310 320 330 340 350
DLNDQVTLLK YGVYEAIFAM LASVMNKDGM LVAYGNGFIT REFLKSLRKP
360 370 380 390 400
FCDIMEPKFD FAMKFNALEL DDSDISLFVA AIICCGDRPG LVNVGHIEKM
410 420 430 440 450
QESIVHVLKL HLQTNHPDDI FLFPKLLQKM ADLRQLVTEH AQLVQIIKKT
460
ESDAHLHPLL QEIYRDMY
Length:468
Mass (Da):52,281
Last modified:October 1, 2000 - v1
Checksum:iD7E9CF6616D7FE4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF163809 mRNA. Translation: AAF80479.1.
AF470455 mRNA. Translation: AAL85322.1.
RefSeqiNP_001001464.1. NM_001001464.1.
UniGeneiGga.4006.

Genome annotation databases

GeneIDi374120.

Similar proteinsi

Entry informationi

Entry nameiQ9I8W4_CHICK
AccessioniPrimary (citable) accession number: Q9I8W4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 22, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)